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Animal Lectin

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Lectins

Abstract

Animal lectins bind to soluble carbohydrates on cell surfaces. The majority of animal lectins are nonenzymatic in activity and usually precipitate glycoconjugates in specific animal cells. It controls protein levels in the blood, modulates cell adhesion to glycoprotein production, and binds soluble extracellular and intracellular glycoproteins. Carbohydrates seen in pathogens that are not recognized by immune system host cells are identified by lectins. Animal lectins have a jelly-like consistency. Animal lectins have a jelly-roll tertiary structure with quaternary connections that vary. P type lectins, C type lectins, I type lectins, Chi lectins, and others are the 15 structural families of animal lectins.

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Abbreviations

AAA:

Anguilla anguilla agglutinin

CD-MPR:

Cation-dependent mannose 6-phosphate receptor

CI-MPR:

Cation-independent mannose 6-phosphate receptor

CLRD:

C type lectin-like receptor domain

CRD:

Carbohydrate recognition domain

ERAD:

Endoplasmic reticulum-associated degradation

FTLD:

F type lectin domain

IGF2R:

Insulin-like growth factor 2 receptor

LMAN2:

Lectin, mannose binding 2

LRR:

Leucine-rich repeats

MAG:

Myelin-associated glycoprotein

MCFD2:

Multicoagulation-factor deficiency 2 protein

MDCK:

Madin-Darby canine kidney

SBD:

Sugar binding domain

TGN:

Trans-Golgi network

TIM:

Triose-phosphate isomerase

VIP-36:

Vesicular integral membrane protein-36

XCGL:

Xenopus oocyte cortical granule lectin

XEEL:

Xenopus embryonic cuticular glycoprotein

zINTLs:

Zebrafish intelectins

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Author information

Authors and Affiliations

  1. Department of Fish Processing Technology, Kerala University of Fisheries and Ocean Studies (KUFOS), Kochi, Kerala, India

    Sahya Narayanan, Akhila Raj Pallan, Akshay Balakrishnan & Eldho J. Paul

  2. Department of Marine Biology, Microbiology and Biochemistry, School of Marine Sciences, Cochin University of Science and Technology, Cochin, Kerala, India

    Preetham Elumalai

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  1. Sahya Narayanan
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  2. Akhila Raj Pallan
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  3. Akshay Balakrishnan
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  4. Eldho J. Paul
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  5. Preetham Elumalai
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Correspondence to Preetham Elumalai .

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Editors and Affiliations

  1. Department of Marine Biology, Microbiology and Biochemistry, School of Marine Sciences, Cochin University of Science and Technology, Cochin, Kerala, India

    Preetham Elumalai

  2. School of Ocean Science and Technology, Kerala University of Fisheries and Ocean Studies, Cochin, Kerala, India

    Sreeja Lakshmi

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Narayanan, S., Pallan, A.R., Balakrishnan, A., Paul, E.J., Elumalai, P. (2021). Animal Lectin. In: Elumalai, P., Lakshmi, S. (eds) Lectins. Springer, Singapore. https://doi.org/10.1007/978-981-16-7462-4_5

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