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Synthesis Biomaterials in Biomedical Applications

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Functional Biomaterials

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Abstract

Biomaterials can be thought of as materials designed to interact with biological systems to evaluate, treat, and replace body tissues. Generally, biomaterials were usually derived from natural sources, like collagen, gelatin, and cotton. Polymer biomaterials are used in various biomedical applications, in which the polymer stays in close contact with cells and tissues for a long time. Although many polymer materials have been tested for different applications, it is recognized that the current range of biomaterials available will not be adequate for the large range of tissue engineering applications such as artificial organs and drug delivery. Synthetic polymers have inherent advantages and disadvantages in the biomedical field they can distribute molecular weights and monomers in different ways. The choice of biomaterials plays an essential role in the design of biomedical products. Although the classic selection criteria for stable and safe implants determine the choice of passive inert materials, any such device can now trigger a cellular response. The chapter describes various polymer biomaterials for drug delivery and tissue engineering synthesis.

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Abbreviations

ADA:

Adenosine deaminase asparaginase

AgSD:

Silver sulfadiazine

AuNPs:

Gold nanoparticle

CNT:

Carbon nanotubes

CONA:

Concanavalin

Cp:

Cloud point

CP:

Conducting polymer

CTA:

Chain transfer agent

DDT:

dl-dithiothreitol

DOX:

Doxorubicin

DVS:

Divinyl sulfate

ECM:

Extracellular matrix

EPC:

Endothelial progenitor cells

FDA:

Food and Drug Administration

FGF:

Fibroblast growth factor

FITC:

Fluorescein isothiocyanate

GSH:

Glutathione

HA:

Hyaluronic acid

HAEC:

Human aortic endothelial cells

HDAC 1:

Histone DeACetylase

HEMA:

Hexamethylenediisocyanate

ICP:

Interfacial polyelectrolyte complex

LBL:

Layer by layer

LCST:

Lower critical solution temperature

LEMS:

Light-emitting diods

LGFC:

Lysozyme-stabilized gold fluorescent cluster

MBTTC:

Methyl 2((((Butylthio) carbonothioyl)thio)propanoate)

MMT:

Montmorillonite

NF:

Nanofiber

NIR:

Near infrared

NP:

Nanoparticle

NPM:

(N-methyl pyrolidone)

PAA:

(Polyacrylic acid)

PAAC:

(Propyl acrylic acid)

PAH:

(Poly(allylamine hydrochloride))

PAMAM:

(Poly(amidoamine))

PANI:

(Polyaniline)

PCL:

(Polycaprolactone)

PDADMAC:

Poly(diallyldimethyl ammonium)

PDGF:

Platelet-derived growth factor

PDLLA:

(Poly(d,l-lactic acid))

PDMAPAAM:

Poly(N,N-dimethylaminopropyl acrylamide)

PECs:

(Polyelectrolyte complex)

PEG:

(Polyethylene glycol)

PEGDA:

(Poly(ethylene glycol) diacrylate)

PEGMA:

(Poly(ethylene glycol) methacrylate)

PEO:

(Polyethylene oxide)

PEO-GMA-DEA:

Poly(ethylene oxide)-block-glycerol monimethacrylate-block-(dimethylamino ethyl methacrylate)

PEO-HEMA-DEA:

Poly(ethylene oxide-block-2-hydroxyethyl methacrylate-block-2-(dimethylamino ethyl methacrylate))

PgA:

(Polygalacturonic acid)

PGA:

(Polyglutamic acid)

PGA:

(Polyglycolide)

PLA:

(Polylactide)

PLGA:

(Poly(lactic acid-co-glycolic acid))

PLLA:

(Poly l-lactic acid)

PMAC:

(Polymethacrylic acid)

PNIPAM:

Poly(N-isopropylacrylamide)

POC:

Point of care

PPO:

(Polypropylene oxide)

PPV:

(Poly(para-phenylene vinylene))

PPy:

(Polypyrrole)

PT:

(Poly thiophene)

PVA:

(Polyvinyl alcohol)

PVP:

(Polyvinyl pyrrolidone)

QY:

Quantum yield

SCL:

Shell cross link

SE:

Silicon tube

SPR:

Surface plasmon resonance

SWCNTs:

Single-walled carbon nanotubes

ZnO:

Zinc oxide

ZoI:

Zone of inhabitation

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Authors and Affiliations

  1. Department of Polymer Engineering and Color Technology, Amirkabir University of Technology, Tehran, Iran

    Shadi Sadat Nasiri & Faramarz Afshar-Taromi

  2. Department of Chemistry, Amirkabir University of Technology, Tehran, Iran

    Zahed Ahmadi

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  1. Shadi Sadat Nasiri
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  2. Zahed Ahmadi
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Correspondence to Zahed Ahmadi .

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  1. Department of Health and Family Welfare, Directorate of Health Services, Kolkata, West Bengal, India

    Sougata Jana

  2. Department of Chemistry, Indira Gandhi National Tribal University, Amarkantak, India

    Subrata Jana

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Nasiri, S.S., Ahmadi, Z., Afshar-Taromi, F. (2022). Synthesis Biomaterials in Biomedical Applications. In: Jana, S., Jana, S. (eds) Functional Biomaterials. Springer, Singapore. https://doi.org/10.1007/978-981-16-7152-4_11

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