Abstract
Actinobacteria are widely known for the production of secondary metabolites, many of which have found application in the clinic. Despite being one of the most extensively explored bacterial phyla, Actinobacteria from polar regions are still overlooked. In this chapter, the taxonomic diversity of Actinobacteria isolated from the poles, their associated secondary metabolites, and the diversity of biosynthetic genes that encode for polyketides and non-ribosomal peptides will be covered.
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Acknowledgments
The authors acknowledge funding from the Portuguese Science and Technology Foundation (FCT) through grants to CM (PTDC/CTA-AMB/30997/2017; PTDC/CTA-AMB/4946/2020), a PhD scholarship to AR (SFRH/BD/140567/2018), and through the project and the Strategic Funding UIDB/04423/2020 and UIDP/04423/2020 through national funds provided by FCT and European Regional Development Fund (ERDF) in the framework of the program PT2020. The authors also acknowledge funding from the structured program of R&D&I ATLANTIDA—Platform for the monitoring of the North Atlantic Ocean and tools for the sustainable exploitation of the marine resources (reference NORTE-01-0145-FEDER-000040), supported by the North Portugal Regional Operational Programme (NORTE2020), through the ERDF.
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Rego, A., de Fátima Carvalho, M., Leão, P., Magalhães, C. (2022). Polar Actinobacteria: A Source of Biosynthetic Diversity. In: Rai, R.V., Bai, J.A. (eds) Natural Products from Actinomycetes. Springer, Singapore. https://doi.org/10.1007/978-981-16-6132-7_3
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