Abstract
Cancer is a global health issue affecting people of all ages. Cancer affecting the women is increasing due to altered life patterns, environmental stress and differences in metabolic activity, and individual physiology. Cervical cancer (CC) which affects the cervix is one of the most common diseases affecting the women and almost 99% of all CC cases are linked to human papillomavirus (HPV) contracted via sexual activity. Early diagnosis of CC is treatable and can be managed effectively even in the advanced stages with appropriate therapeutic strategy. With the scientific advancement there are three different vaccines that have been prequalified and provide protection against HPV-associated CC (Stelzle et al., Lancet Glob Health 9:e161–e169, 2021). Symptoms of CC include irregular bleeding between periods, postmenopausal spotting or bleeding, and increased vaginal discharge. In advanced stages of the disease symptoms like pelvic pain, reduction of body weight, reduced food intake, and edema of lower extremities can be manifested. WHO’s goal is to eliminate this global health issue of CC by 2030 among the low and lower middle class income countries (WHO, United Nations Gen Assem 2:1–3, 2020).
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Santosh, S.W., Freddy, A.J., Winkins, D. (2022). Oxidative Stress in the Pathogenesis of Cervical Cancer. In: Chakraborti, S. (eds) Handbook of Oxidative Stress in Cancer: Therapeutic Aspects. Springer, Singapore. https://doi.org/10.1007/978-981-16-5422-0_277
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DOI: https://doi.org/10.1007/978-981-16-5422-0_277
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