Abstract
Different shaped PbS nanoparticles are synthesized at room temperature by using reagents, lead chloride (PbCl2), sulfur powder (S), and sodium borohydride (NaBH4), in the ethylenediamine medium. NaBH4 has acted as a reducing agent, whereas ethylenediamine is used as a capping agent. The grown PbS nanoparticles are spherical (7 nm size) for the reagent ratio of PbCl2, S, NaBH4 as 1:1:1. and grown PbS nanoparticles are cubical shape (13 nm size) for the reagent ratio of PbCl2, S, NaBH4 as 1:1:3. The grown PbS nanoparticles are characterized structurally and optically. The interaction and formation of the bio-conjugate of bovine serum albumin with PbS nanomaterials are studied for biomedical application. The interaction, complexion process, and conformational changes of bovine serum albumin with PbS nanomaterials are quantified by the photophysical and structural study. PbS nanomaterials enable the aggregation of bovine serum albumin by the way of unfolding. The interaction and the bioconjugate formation of albumin with PbS nanoparticles are investigated using optical spectroscopy, TEM. UV–VIS–NIR shows the binding process that occurred between albumin and PbS samples.
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Acknowledgements
The authors would like to acknowledge the DST-FIST-sponsored Department of Physics, Vidyasagar University, for providing various instrumental facilities.
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Mishra, A.K., Bhunia, A.K., Saha, S. (2021). Comparison of Protein Interaction with Different Shaped PbS Nanoparticles and Corona Formation. In: Sengupta, S., Dey, S., Das, S., Saikia, D.J., Panda, S., Podila, R. (eds) Selected Progresses in Modern Physics. Springer Proceedings in Physics, vol 265. Springer, Singapore. https://doi.org/10.1007/978-981-16-5141-0_6
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