Skip to main content

Medical Oncology in Cancer Treatment

  • Chapter
  • First Online:
Cancer Diagnostics and Therapeutics

Abstract

Malignancy is the second most common disease worldwide after heart disease. Cancer of any subsite is generally treated through one or more modalities of surgery, chemotherapy, and radiotherapy. Surgery and radiotherapy are local forms of treatments, but chemotherapy is systemic. The specialization in the field of systemic therapy is called medical oncology. The concept of medical oncology has come into the picture a couple of decades back. Chemotherapy, hormonal therapy, and targeted therapy have been established for the treatment of cancer. Immunotherapy and gene therapy are still in the investigational phase. Many new molecules are getting approval from the USFDA every year and changing the treatment protocol continuously.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 189.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 249.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 249.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  • Alfarouk KO, Stock CM, Taylor S, Walsh M, Muddathir AK, Verduzco D, Bashir AH, Mohammed OY, Elhassan GO, Harguindey S, Reshkin SJ (2015) Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp. Cancer Cell Int 15(1):1–13

    Article  CAS  Google Scholar 

  • Bisht M, Bist SS, Dhasmana DC (2010) Biological response modifiers: current use and future prospects in cancer therapy. Indian J Cancer 47(4):443

    Article  CAS  PubMed  Google Scholar 

  • Chabner BA, Roberts TG (2005) Chemotherapy and the war on cancer. Nat Rev Cancer 5(1):65–72

    Article  CAS  PubMed  Google Scholar 

  • Chu E, Sartorelli AC (2004) Cancer chemotherapy. Basic Clin Pharmacol 9:898–930

    Google Scholar 

  • DeVita VT, Chu E (2008) A history of cancer chemotherapy. Cancer Res 68(21):8643–8653

    Article  CAS  PubMed  Google Scholar 

  • Goldie JH, Coldman AJ (1979) A mathematic model for relating the drug sensitivity of tumors to their spontaneous mutation rate. Cancer Treat Rep 63(11–12):1727–1733

    CAS  PubMed  Google Scholar 

  • Gonzalez H, Hagerling C, Werb Z (2018) Roles of the immune system in cancer: from tumor initiation to metastatic progression. Genes Dev 32(19–20):1267–1284

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Govindan R, DeVita VT (eds) (2009) DeVita, Hellman, and Rosenberg's cancer: principles & practice of oncology review. Lippincott Williams & Wilkins

    Google Scholar 

  • Hall EJ, Giaccia AJ (2006) Radiobiology for the radiologist (vol. 6)

    Google Scholar 

  • Hartwell LH, Hopfield JJ, Leibler S, Murray AW (1999) From molecular to modular cell biology. Nature 402(6761):C47–C52

    Article  CAS  PubMed  Google Scholar 

  • Jain KK (2002) Personalized medicine. Curr Opin Mol Ther 4(6):548–558

    CAS  PubMed  Google Scholar 

  • Mcleod DG (2003) Hormonal therapy: historical perspective to future directions. Urology 61(2):3–7. (Mcleod, 2003)

    Article  PubMed  Google Scholar 

  • Mitchison DA (1979) Basic mechanisms of chemotherapy. Chest 76(6):771–780

    Article  CAS  PubMed  Google Scholar 

  • Nagai H, Kim YH (2017) Cancer prevention from the perspective of global cancer burden patterns. J Thorac Dis 9(3):448

    Article  PubMed  PubMed Central  Google Scholar 

  • Sedgwick P (2011) Phases of clinical trials. BMJ 343

    Google Scholar 

  • Tannock IF, Hill RP, Bristow RG, Harrington L (eds) (1987) The basic science of oncology. Pergamon Press, New York, p 398

    Google Scholar 

  • Tripathi KD (1994) Essentials of medical pharmacology. Indian J Pharmacol 26(2):166

    Google Scholar 

  • Wirth T, Ylä-Herttuala S (2014) Gene therapy used in cancer treatment. Biomedicine 2(2):149–162. https://doi.org/10.3390/biomedicines2020149

    Article  Google Scholar 

  • Wu HC, Chang DK, Huang CT (2006) Targeted therapy for cancer. J Cancer Mol 2(2):57–66

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2022 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Saha, M. (2022). Medical Oncology in Cancer Treatment. In: Basu, S.K., Panda, C.K., Goswami, S. (eds) Cancer Diagnostics and Therapeutics . Springer, Singapore. https://doi.org/10.1007/978-981-16-4752-9_12

Download citation

Publish with us

Policies and ethics