Abstract
Bioinformatics is an amalgamation of multidisciplinary sciences that has played a significant role in extending tremendous benefits through comprehending the biological information in a quick and precise manner. The recent opening of multiple “omics” technologies have provided plethora of information; the bioinformatics has provided means to process this humongous information in more systematic and precise ways to provide potentially beneficial biological information. Continuing efforts and zeal that set the premise for mapping of Haemophilus influenza genome potentially led to successful decoding of the human genomic information in a very ambitious human genome project. The systematic breakdown and understanding of huge nucleic acid sequence data out of human genome has been an important milestone of this field. Taking on with the futuristic and additional developments in the field of bioinformatics has now brought this field at the stage where now functional outcome has proceeded from mere prediction to a reality. All the aspects of biological functioning, viz., genomics, proteomics, metabolomics, transcriptomics, RNAiomics, and kinomics to drug development, etc. are now being revolutionized, (courtesy of the bioinformatics).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Amaral AM, Reis MS, Silva FR (2007) O programa BLAST: guiaprático de utilização, 1st edn. EmbrapaRecursosGenéticos e Biotecnologia. EMBRAPA, Brasília
Baxevanis AD (2001) The molecular biology, database collection: an updated compilation of biological database resources. Nucleic Acids Res 29(1):1–10. https://doi.org/10.1093/nar/29.1.1
Fleischmann RD, Adams MD, White O, Clayton RA, Kirkness EF, Kerlavage AR et al (1995) Whole-genome random sequencing and assembly of Haemophilus influenzae Rd. Science 269:496512
International Human Genome Sequencing Consortium (2001) Initial sequencing and analysis of the human genome. Nature 409:860921
Luscombe NM, Greenbaum D, Gerstein M (2001) What is bioinformatics? A proposed definition and overview of the field. Methods Inf Med 40:346–358. https://doi.org/10.1053/j.ro.2009.03.010
Manohar P, Shailendra S (2012) Protein sequence alignment: a review. World Appl Program 2:141–145
Neerincx PB, Leunissen JA (2005) Evolution of web services in bioinformatics. Brief Bioinform 6(2):178–188
Pevsner J (2015) Bioinformatics and functional genomics, 3rd edn. Wiley, Chichester
Ritchie MD, Holzinger ER, Li R, Pendergrass SA et al (2015) Methods of integrating data to uncover genotype phenotype interactions. Nat Rev Genet 16:85–97. https://doi.org/10.1038/nrg3868
Schmidt A, Forne I, Imhof A, Venter JC, Adams MD, Myers EW, Li PW, Mural RJ, Sutton GG et al (2001) The sequence of the human genome. Science 291:130451
Subramanian G, Adams MD, Venter JC, Broder S (2001) Implications of the human genome for understanding human biology and medicine. JAMA 286:2296306
Zhao W, Langfelder P, Fuller T, Dong J et al (2010) Weighted gene coexpression network analysis: state of the art. J Biopharm Stat 20:281–300. https://doi.org/10.1080/10543400903572753
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2022 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
About this chapter
Cite this chapter
Puri, V., Puri, S., Sobti, R.C. (2022). Bioinformatics: The Interactome of Multidisciplinary Approaches. In: Sobti, R., Sobti, A. (eds) Biomedical Translational Research. Springer, Singapore. https://doi.org/10.1007/978-981-16-4345-3_7
Download citation
DOI: https://doi.org/10.1007/978-981-16-4345-3_7
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-16-4344-6
Online ISBN: 978-981-16-4345-3
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)