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3D Bioprinting of Tissues and Organs: A New Paradigm in Regenerative Medicine and Biomedical Engineering

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Biomedical Translational Research

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Abstract

3D bioprinting is the most popular additive manufacturing method, in which solid objects are constructed by depositing several layers in sequence for the fabrication of biostructures. Bioprinted structures, like tissues, organs, and Organ-on-chip, in 3D, are now widely used to study and understand the functions of the human body. The 3D bioprinted structures are closely similar to naturally occurring biologics systems, and studies performed on 3D biostructures can be more biologically relevant than in vitro studies conducted in 2D. 3D bioprinting has advanced over the years and is commonly used in tissue engineering and regenerative medicine. The fabrication of biomaterials like cells, tissues, and organs using 3D bioprinting is becoming an alternative and favorable tissue and organ transplantation approach. Bioprinting is a relatively novel method and holds great promise but has several challenges and limitations. To this end, this chapter summarizes the concept of 3D bioprinting, bioinks and their classification, different methods of bioprinting, and their applications in areas of health, pharmaceutical science, and biomedical engineering. The chapter also highlights the challenges associated with the clinical utilization of 3D bioprinting. 3D bioprinting and its applications in personalized medicine and tissue bioengineering are continuously growing. In the future, this technology could provide advanced tools to the researchers to develop targeted treatment and improve patient outcomes.

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Authors and Affiliations

  1. University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India

    Kanwaljit Chopra, Sandip V. Pawar, Manju Maurya, Tavish Gupta & Jatinder Dhaliwal

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  1. Kanwaljit Chopra
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  2. Sandip V. Pawar
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  3. Manju Maurya
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  4. Tavish Gupta
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  5. Jatinder Dhaliwal
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Editors and Affiliations

  1. Department of Biotechnology, Panjab University, Chandigarh, Chandigarh, India

    R.C. Sobti

  2. Lund University, Lund, Sweden

    Aastha Sobti

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Chopra, K., Pawar, S.V., Maurya, M., Gupta, T., Dhaliwal, J. (2022). 3D Bioprinting of Tissues and Organs: A New Paradigm in Regenerative Medicine and Biomedical Engineering. In: Sobti, R., Sobti, A. (eds) Biomedical Translational Research. Springer, Singapore. https://doi.org/10.1007/978-981-16-4345-3_15

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