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Chinese Herbal Medicine and Targeted Delivery Strategy for the Treatment of Kidney Disease

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Novel Drug Delivery Systems for Chinese Medicines

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Abstract

Chronic kidney disease (CKD) is a worldwide public health issue with poor treatment outcomes and high medical costs. Current treatment options for CKD are limited. A large part of the world’s population has been using Chinese herbal medicine (CHM) for kidney disease treatment, and many active compounds have been identified as useful for CKD. Besides, several well-designed kidney-targeted drug delivery systems have been developed to improve drug efficacy and safety in CKD therapy. In this chapter, the structure and physiological function of the kidney are reviewed. The efficacy of several CHMs, supported by either clinical evidence or experimental studies, and renal targeting delivery strategies are presented. Current challenges for further research are also discussed.

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Authors and Affiliations

  1. Jiangsu Key Laboratory for Functional Substance of Chinese Medicine, Jiangsu Engineering Research Center for Efficient Delivery System of TCM, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, P. R. China

    Lei Zhang, Lina Gao & Hongzhi Qiao

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  1. Lei Zhang
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  2. Lina Gao
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Correspondence to Hongzhi Qiao .

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  1. Department of Pharmaceutical Sciences, Shanghai University of Traditional Chinese Medicine, Shanghai, China

    Nianping Feng

  2. School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong kong, China

    Zhijun Yang

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Zhang, L., Gao, L., Qiao, H. (2021). Chinese Herbal Medicine and Targeted Delivery Strategy for the Treatment of Kidney Disease. In: Feng, N., Yang, Z. (eds) Novel Drug Delivery Systems for Chinese Medicines. Springer, Singapore. https://doi.org/10.1007/978-981-16-3444-4_7

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