Abstract
Riboswitches are one of the most compact and efficient gene regulatory elements. These structured RNAs bind small molecule ligands to regulate gene expression and have been discovered in all three domains of life. The study of natural riboswitches has given many fundamental insights into molecular recognition by RNA, RNA structure and conformational dynamics, and mechanisms of gene regulation at the RNA level.
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Banuelos Jara, B., Hammond, M.C. (2023). Natural Riboswitches. In: Sugimoto, N. (eds) Handbook of Chemical Biology of Nucleic Acids. Springer, Singapore. https://doi.org/10.1007/978-981-16-1313-5_91-1
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