Abstract
The COVID-19 pneumonia is a specific infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) which is a single-stranded positive-strand RNA virus and has not been found in humans previously [1–3]. Since the outbreak of COVID-19 in January 2020, it has spread rapidly among general population through respiratory droplets and indirect or direct contact, especially in middle-aged and elderly people [4–6]. The incubation period of COVID-19 pneumonia is 1–14 days, usually 3–7 days. The main clinical manifestations are fever, fatigue, dry cough, and muscle soreness, a few accompanied by nasal congestion, runny nose, diarrhea, and so on [7]. Most patients present with mild clinical symptoms initially, while for some severe or critically ill patients, symptoms can manifest as dyspnea and hypoxemia within a week and progress to respiratory failure and death [8, 9].
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Li Q. The 2019-nCoV Outbreak joint Field Epidemiology Investigation team, Notes form the field: an outbreak of NCIP (2019-nCoV) infection in China-Wuhan, Hubei Province, 2019–2020. China CDC Weekly. 2020;2:79–80.
Dong N, Yang XM, Ye LW, et al. Genomic and protein structure modelling analysis depicts the origin and infectivity of 2019-nCoV, a new coronavirus which caused a pneumonia outbreak in Wuhan, China. bioRxiv 2020.01.20.913368; https://doi.org/10.1101/2020.01.20.913368.
Michael L, Vincent M. Functional assessment of cell entry and receptor usage for lineage B β-coronaviruses, including 2019-nCoV. bioRxiv 2020.01.22.915660; https://doi.org/10.1101/2020.01.22.915660.
Li Q, Guan WH, Wu P, et al. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. N Engl J Med. https://doi.org/10.1056/NEJMoa2001316.
Chan JF, Yuan S, Kok KH, et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet. 2020 (Epub ahead of print).
Ju LE, Ri O, Christian L, et al. Pattern of early human-to-human transmission of Wuhan 2019-nCoV. Althaus. bioRxiv 2020.01.23.917351; https://doi.org/10.1101/2020.01.23.917351.
Paules CI, Marston HD, Fauci AS. Coronavirus infections–more than just the common cold. JAMA. 2020;323(8):707–8. https://doi.org/10.1001/jama.2020.0757.
Huang CL, Wang YM, Li XW, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan China. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020. ISSN0140-6736, https://doi.org/10.1016/S0140-6736(20)30183-5., http://www.sciencedirect.com/science/article/pii/S0140673620301835.
Chen NS, Zhou M, Dong X, et al. 2019 novel coronavirus pneumonia in Wuhan, China a descriptive study. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020. ISSN0140-6736, https://doi.org/10.1016/S0140-6736(20)30211-7., http://www.sciencedirect.com/science/article/pii/S0140673620302117.
Wei JG, Zheng YN, Yu H, et al. Clinical characteristics of 2019 novel coronavirus infection in China. https://medrxiv.org/content/https://doi.org/10.1101/2020.02.06.20020974v1.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2021 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
About this chapter
Cite this chapter
Gan, Q., Hu, T., Jiang, S. (2021). Role of CT and CT Features of Suspected COVID-19 Patients (PCR Negative). In: Liu, J., Tang, X., Lei, C. (eds) Atlas of Chest Imaging in COVID-19 Patients. Springer, Singapore. https://doi.org/10.1007/978-981-16-1082-0_7
Download citation
DOI: https://doi.org/10.1007/978-981-16-1082-0_7
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-16-1081-3
Online ISBN: 978-981-16-1082-0
eBook Packages: MedicineMedicine (R0)