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Enhancement of the U-net Architecture for MRI Brain Tumor Segmentation

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Next Generation of Internet of Things

Part of the book series: Lecture Notes in Networks and Systems ((LNNS,volume 201))

Abstract

The magnetic resonance images (MRI) brain tumor segmentation is one of the most difficult medical images segmentation, and it has many challenges because the tumor has no specific shape or size, not found in a specific place of the brain and contains three sub-regions (full tumor FT, tumor core TC, and enhanced tumor ET). The manual segmentation is extremely difficult and prone to mistakes. In this research, the semantic segmentation is used by implementing the U-net model, which is a fully convolutional network (FCN) algorithm on BraTS 2018 that contains four modalities (T1, T2, T1c, Flair). The U-net model is used two time: The first is using 9-layers U-net with some enhancements on the original model for segment the full tumor, and the second is using 7-layers U-net model for segment the tumor core and enhanced tumor. The results were promised by segmenting the brain tumor within three sub-regions (full tumor, tumor core, and enhanced tumor), and the results were evaluated using standard brain tumor segmentation metrics. The proposed system achieves mean dice similarity coefficient metric; it is 0.87, 0.76, and 0.71 for full tumor, tumor core, and enhanced tumor, respectively. Additionally, the median dice similarity coefficient metric is 0.90, 0.84, and 0.80 for full tumor, tumor core, and enhanced tumor, respectively.

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References

  1. Balafar MA, Ramli AR, Saripan MI, Mashohor S (2010) Review of brain MRI image segmentation methods. Artif Intell Rev 33(3):261–274

    Article  Google Scholar 

  2. Ben naceur M, Saouli R, Akil M, Kachouri R (2018) Fully automatic brain tumor segmentation using end-to-end incremental deep neural networks in MRI images. Comput Methods Programs Biomed 166:39–49

    Google Scholar 

  3. Wang, G, Li W, Ourselin S, Vercauteren T (2019) Automatic brain tumor segmentation using convolutional neural networks with test-time augmentation. In: BT—Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries, pp 61–72

    Google Scholar 

  4. Gholami A et al (2018) A novel domain adaptation framework for medical image segmentation. In International MICCAI Brainlesion workshop, pp 289–298

    Google Scholar 

  5. Myronenko A (2019) 3D MRI brain tumor segmentation using autoencoder regularization. In: Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), LNCS, vol 11384, pp 311–320

    Google Scholar 

  6. Weninger L, Rippel O, Koppers S, Merhof D (2019) Segmentation of brain tumors and patient survival prediction: methods for the BraTS 2018 challenge. In: BT—Brainlesion: Glioma, multiple sclerosis, stroke and traumatic brain injuries, pp 3–12

    Google Scholar 

  7. Bakas S, Reyes M, Jakab A, Bauer S, Rempfler M, Crimi A, Takeshi Shinohara R, Berger C, Ha SM, Rozycki M, Prastawa M, Alberts E, Lipkova J, Freymann J, Kirby J, Bil M (2019) Identifying the best machine learning algorithms for brain tumor segmentation, progression assessment, and overall survival prediction in the BRATS challenge, vol v3. arXiv.org

    Google Scholar 

  8. Marcinkiewicz M, Nalepa J, Lorenzo PR, Dudzik W, Mrukwa G (2019) Segmenting brain tumors from MRI using cascaded multi-modal U-nets. In: BT—Brainlesion: Glioma, multiple sclerosis, stroke and traumatic brain injuries, pp 13–24

    Google Scholar 

  9. Kori A, Soni M, Pranjal B, Khened M, Alex V, Krishnamurthi G (2019) Ensemble of fully convolutional neural network for brain tumor segmentation from magnetic resonance images. In: Brainlesion: Glioma, multiple sclerosis, stroke and traumatic brain injuries, pp 485–496

    Google Scholar 

  10. Benson E, Pound MP, French AP, Jackson AS, Pridmore TP (2019) Deep hourglass for brain tumor segmentation. In: Brainlesion: Glioma, multiple sclerosis, stroke and traumatic brain injuries, pp 419–428

    Google Scholar 

  11. Carver E et al (2019) Automatic brain tumor segmentation and overall survival prediction using machine learning algorithms. In: Brainlesion: Glioma, multiple sclerosis, stroke and traumatic brain injuries, pp 406–418

    Google Scholar 

  12. Yang H-Y, Yang J (2019) Automatic brain tumor segmentation with contour aware residual network and adversarial training. In: Brainlesion: Glioma, multiple sclerosis, stroke and traumatic brain injuries, pp 267–278

    Google Scholar 

  13. Iqbal S, Ghani MU, Saba T, Rehman A (2018) Brain tumor segmentation in multi-spectral MRI using convolutional neural networks (CNN). Microsc Res Tech 81(4):419–427

    Article  Google Scholar 

  14. Yu C, Wang J, Peng C, Gao C, Yu G, Sang N (2018) Learning a discriminative feature network for semantic segmentation. In: Proceedings of the IEEE conference on computer vision and pattern recognition, pp 1857–1866

    Google Scholar 

  15. Ronneberger O, Fischer P, Brox T (2015) U-net: convolutional networks for biomedical image segmentation. In: International conference on medical image computing and computer-assisted intervention, pp 234–241

    Google Scholar 

  16. Kolařík M, Burget R, Uher V, Říha K, Dutta MK (2019) Optimized high resolution 3D dense-U-Net network for brain and spine segmentation. Appl Sci 9(3):404

    Article  Google Scholar 

  17. Leng J, Liu Y, Zhang T, Quan P, Cui Z (2019) Context-aware U-net for biomedical image segmentation

    Google Scholar 

  18. Tuan TA, Tuan TA, Bao PT (2019) Brain tumor segmentation using bit-plane and UNET. In: Brainlesion: Glioma, multiple sclerosis, stroke and traumatic brain injuries, pp 466–475

    Google Scholar 

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Correspondence to Assef Raad Hmeed .

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Hmeed, A.R., Aliesawi, S.A., Jasim, W.M. (2021). Enhancement of the U-net Architecture for MRI Brain Tumor Segmentation. In: Kumar, R., Mishra, B.K., Pattnaik, P.K. (eds) Next Generation of Internet of Things. Lecture Notes in Networks and Systems, vol 201. Springer, Singapore. https://doi.org/10.1007/978-981-16-0666-3_28

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