Abstract
Lipids are biomolecules essential for the life. They play different important roles in the nature. Therefore, its degradation has been influenced by internal or external factors. Although lipids have shown be fundamental for life, its accumulation can be hazardous for the health. Recent anecdotal studies provide information about the degradation of lipids by enzymes produced by different microorganisms. Besides, microorganism as bacteria and fungi encompasses a wide range of species that can produce positive or negative effects on the environment. Some report highlighted the better benefits of enzymes derived from microorganisms than those derived from other species such as animals and vegetables. Additionally, external factors such as pH, temperatures, substrate, and metallic ions generate important roles during the lipolitic degradation. This chapter describes the biochemistry degradation of the lipids (fatty acids) and some examples related to microorganism species and their source producing fundamental enzymes as well as a wide range of applications approached into industrial, biotechnological, and medicine.
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References
Abbas H, Hiol A, Deyris V, Coumeau L (2002) Isolation and characterization of an extracellular lipase from. Enzym Microb Technol 31(7):968–975
Abdelli F, Jardak M, Elloumi J, Stien D, Cherif S, Mnif S, Aifa S (2019) Antibacterial, anti-adherent and cytotoxic activities of surfactin(s) from a lipolytic strain Bacillus safensis F4. Biodegradation 30:287–3e00
Aldred EM, Buck C, Vall K (2009) Lipids. In: Pharmacology. Churchill Livingstone/Elsevier, Edinburgh, Scotland, pp 73–80
Alford JA, Pierce DA, Suggs FG (1964) Activity of microbial lipases on natural fats and synthetic triglycerides. J Lipid Res 5(3):390–394
Allen WV (1976) Biochemical aspects of lipid storage and utilization in animals. Am Zool 16(4):631–647. https://doi.org/10.1093/icb/16.4.631
Almyasheva NR, Shuktueva MI, Petrova DA, Kopitsyn DS, Kotelev MS, Vinokurov VA, Novikov AA (2018) Biodiesel fuel production by Aspergillus Niger whole-cell biocatalyst in optimized medium. Mycoscience 59(2):1–6
Arpingny JL, Jaeger KE (1999) Bacterial lipolytic enzymes: classification and properties. Biochemical Journal 343(1):177
Becker P (2010) Understanding and optimizing the microbial degradation of olive oil: a case study with the thermophilic bacterium Geobacillus Thermoleovorans IHI-91. In: Preedy VR (ed) Olives and olive oil in health and disease prevention. Elsevier Acad Press, Amsterdam, Netherlands, pp 377–386
Borda-Molina D, Montaña JS, Zambrano MM, Baena S (2017) Mining lipolytic enzymes in community DNA from high Andean soils using a targeted approach. Antonie Van Leeuwenhoek 110(8):1035–1051
Cardenas F, de Castro MS, Sanchez-Montero JM, Sinisterra JV, Valmaseda M, Elson SW, Alvarez E (2001) Novel microbial lipases: catalytic activity in reactions in organic media. Enzyme and Microbial Technology 28:145–154
Carrazco-Palafox J, Rivera-Chavira BE, RamĂrez-Baca N, Manzanares--Papayanopoulos LI, Nevárez-MoorillĂłn GV (2018) Improved method for qualitative screening of lipolytic bacterial strains. MehodsX 5:68–74
Casas-Godoy L, Bordes F, Gasteazoro F, Marty A (2018) Lipases. In: Sandoval G (ed) An overview: methods and protocols. Lipases and phospholipases. Humana Press, New York, United States, pp 1–8
Celligoi MAPC, Baldo C, De Melo MR, Gasparin FGM, Marques TA, De Barros M (2017) Lipase properties, functions and food applications. Microb Enzym Technol Food Appl:214–240
Chauhan M, Chauhan RS, Garlapati VK (2013) Evaluation of a new lipase from Staphylococcus sp. for detergent additive capability. Biomed Research International:374967
Chawla A, Repa JJ, Evans RM, Mangelsdorf DJ (2001) Nuclear receptors and lipid physiology: opening the X-files. Science 294:1866–1870
Chiofalo B, Lo Presti V (2012) Sampling techniques for the determination of volatile components in food of animal origin. In: Pawliszyn J (ed) Comprehensive sampling and sample preparation: analytical techniques for scientists, vol 4. Academic Press, Saint Louis
Darnoko D, Cheryan M (2000) Kinetics of palm oil transesterification in a batch reactor. Journal of the American Oil Chemists Society 77(12)
Dinasarapu AR, Saunders B, Ozerlat I, Azam K, Subramaniam S (2011) Signaling gateway molecule pages--a data model perspective. Bioinformatics 27(12):1736–1738
El Soda M, Law J, Tsakalidou E, Kalantzopoulos A (1995) Lipolytic activity of cheese related microorganisms and its impact on cheese flavour. Developments in Food Science 37:1823–1847
Fickers P, Benetti P, Waché Y, Marty A, Mauersberger S, Smit M, Nicaud J (2005) Hydrophobic substrate utilisation by the yeast Yarrowia lipolytica, and its potential. FEMS Yeast Research 5:527–543
Furini G, Berger JS, Campos JAMVDSST, Germani JC (2018) Production of lipolytic enzymes by bacteria isolated from biological effluent treatment systems. An Acad Bras Cienc 90(3):2955–2965
Glass JE, Swift G (1989) Agricultural and synthetic polymers, biodegradation and utilization, Simposium Series 433. American Chemical Society, Washington, DC
Gopinath SCB, Hilda A, Anbu P (2005) Extracellular enzymatic activity profiles in fungi isolated from oil-rich environments. Mycoscience 46(2):119–126
Gopinath SCB, Anbu P, Lakshmipriya T, Hilda A (2013) Strategies to characterize fungal lipases for applications in medicine and dairy industry. BioMed Research International 154549:1–10
Gross RA, Kalra B, Kumar A (2001) Polyester and polycarbonate synthesis by in vitro enzyme catalysis. Appl Microbiol Biotechnol 55(6):655–660
Gu JD, Ford TE, Miltton DB, Mitchell R (2000) Microbial degradation and deterioration of polymeric materials. In: Revie RW (ed) Uhlig corrosion handbook. John Wiley & Sons, New York
Gunasekaran V, Das D (2005) Lipase fermentation: progress and prospects. Indian J Biotechnol 4:437–445
Gupta R, Gupta N, Rathi P (2004) Bacterial lipases: an overview of production, purification and biochemical Properties. Appl Microbiol Biotechnol 64(6):763–781
Gurr MI, Harwood JL (1991) Lipid biochemistry, 4th edn. Chapman & Hall, London
Haba E, Bresco O, Ferrer C, Marqués A, Busquets M, Manresa A (2000) Isolation of lipase-secreting bacteria by deploying used frying oil as selective substrate. Enzym Microb Technol 26(1):40–44
Hasan F, Shah AA, Hameed A (2006) Industrial applications of microbial lipases. Enzym Microb Technol 39(2):235–251
Hemachander C, Puvanakrishnan R (2000) Lipase from Ralstonia pickettii as an additive in laundry detergent formulations. Process Biochem 35(8):809–814
Iso M, Chen B, Eguchi M, Kudo T, Shrestha S (2001) Production of biodiesel fuel from triglycerides and alcohol using immobilized lipase. J Mol Catal B Enzym 16(1):53–58
Jaeger KE, Eggert T (2002) Lipases for biotechnology. Curr Opin Biotechnol 13(4):390–397
Jambrak AR, Škevin D (2017) Lipids. In: Nutraceutical and functional food components. Academic Press, London, United Kingdom, pp 103–128
Jensen RG, DeJong FA, Clark RM (1983) Determination of lipase specificity. Lipids 18(3):239–252
Jones PM, Bennett MJ (2017) Disorders of mitochondrial fatty acid β-oxidation. In: Garg U, Smith LD (eds) Biomarkers in inborn errors of metabolism. Elsevier Inc, United States, pp 87–101
Kennedy K (2007) Lipids. In: Enna JS (ed) xPharm: the comprehensive pharmacology reference. Elsevier, Amsterdam, Netherlands, pp 1–6
Kenthorai Raman J, Abang S, Poncelet D, Chan E, Ravindra P (2008) Production of biodiesel using immobilized Lipase—A critical review. Crit Rev Biotechnol 28(4):253–264
Kresge N, Simoni RD, Hill RL (2010) JBC historical perspectives: Lipid biochemistry. J Biol Chem:1–2
Le Borgne F, Demarquoy J (2012) Interaction between peroxisomes and mitochondria in fatty acid metabolism. Open J Mol Integr Physiol 2(1):27–33. https://doi.org/10.4236/ojmip.2012.21005
Lipids (2000) Lethbridge University, pp. 380–394
Lotrakul P, Dharmsthiti S (1997) Purification and characterization of lipase from Aeromonas Sobria LP004. J Biotechnol 54(2):113–120
Lucretia R, Tamara B, Roshini G (2014) Method optimization for denaturing gradient gel electrophoresis (DGGE) analysis of microflora from Eucalyptus sp. wood chips intended for pulping. Afr J Biotechnol 13(3):356–365
Malinauskas T (2008) Docking of fatty acids into the WIF domain of the human Wnt inhibitory Factor-1. Lipids 43(3):227–230
Malinauskas T, Aricescu AR, Lu W, Siebold C, Jones EY (2011) Modular mechanism of Wnt signaling inhibition by Wnt inhibitory factor 1. Nat Struct Mol Biol 18(8):886–893
Man X, Sini M, Obbard JP (2009) Biodiesel fuel production via transesterification of oils using lipase biocatalyst. GCB Bioenergy 1(2):115–125
Mandal A (2019) Lipid biological functions. News-Medical; Retrieved on July 13, 2020 from https://www.news-medical.net/life-sciences/Lipid-Biological-Functions.aspx
Mannaerts GP, Van Veldhoven PP, Casteels M (2000) Peroxisomal Lipid degradation via β- and α-oxidation in mammals. Cell Biochem Biophys 32:73–87. https://doi.org/10.1385/CBB:32:1-3:73
Melser S, Lavie J, Bénard G (2015) Mitochondrial degradation and energy metabolism. Biochim Biophys Acta Mol Cell Res 1853(10):2812–2821. https://doi.org/10.1016/j.bbamcr.2015.05.010
Menaa F, Menaa B, Kahn BA, Menaa A (2016) Trans fat and risks of cardiovascular diseases: facts or artifacts. In: Watson RR, Meester F (eds) Handbook of lipids in human function. AOCS Press, Arizona, United States, pp 23–25
Muro E, Atilla-gokcumen GE, Eggert US, Bement W (2014) Lipids in cell biology: how can we understand them better ? Mol Biol Cell 25:1819–1823
Oyedele SA, Ayodeji AO, Bamidele OS, Ajele JO, Fabunmi TB (2019) Enhanced lipolytic activity potential of mutant Bacillus niacini EMB-5 grown on palm oil mill effluent (POME) and biochemical characterization of purified lipase. Biotechnology 18:101017
Peil G, Kuss AV, Rave A, Villareal J, Hernándes YML, Nascente PS (2016a) Bioprospecting of lipolytic microorganisms obtained from industrial effluents. An Acad Bras Cienc 88(3):1678–2690
Peil GHS, Kuss AV, Rave AFG, Villareal JPV, Hernandes YML, Nascente P (2016b) Bioprospecting of lipolytic microorganisms obtained from industrial effluents. An Acad Bras Ciênc 88(3):1769–1779
Pinotti LM, Lacerda JX, Oliveira MM, Teixeira RD, Rodrigues C, Cassini STA (2017) Production of lipolytic enzymes using. Chemical Engineering Transactions 56:1897–1902
Popoola B, Onilude A (2017) Microorganisms associated with vegetable oil polluted soil. Adv Microbiol 7(5):377–386
Prasad MP (2014) Production of lipase enzyme from Pseudomonas aeruginosa isolated. Int J Pure Appl Biosc 2(1):77–81
Pratush A, Gupta A (2016) Bacterial lipases: production strategies and industrial applications bacterial lipases: production strategies and industrial applications. Microbiol Appl:64–83
Qiao Y, Zhao X, Zhu J, Tu R, Dong L, Wang L, Du W (2018) Fluorescence-activated droplet sorting of lipolytic microorganisms using a compact optical system. Lab Chip 18:190–196
Rameshwaram NR, Singh P, Ghosh S, Mukhopadhyay S (2018) Lipid metabolism and intracellular bacterial virulence: key to next-generation therapeutics. Future Microbiology 13(11):1301–1328
Ramnath L, Sithole B, Govinden R (2017) Identification of lipolytic enzymes isolated from bacteria indigenous to Eucalyptus wood species for application in the pulping industry. Biotechnology Reports 15:114–124
Samoylova YV, Sorokina KN, Piligaev AV, Parmon VN (2019) Application of bacterial thermostable lipolytic enzymes in the modern biotechnological processes: a review. Catal Ind 11(2):168–178
Sandi J, Mata-Araya I, Aguilar F (2020) Diversity of Lipase producing microorganisms from tropical oilseeds Elaeis guineensis, Ricinus communis, and Jatropha curcas L. from Costa Rica. Curr Microbiol 77(6):1–10
Saraswat R, Verma V, Sistla S, Bhushan I (2017) Evaluation of alkali and thermotolerant lipase from an indigenous isolated Bacillus strain for detergent formulation. Electron J Biotechnol 30:33–38
Saxena R, Sheoran A, Giri B, Davidson WS (2003) Purification strategies for microbial lipases. J Microbiol Methods 52(1):1–18
Sayali P, Satpute S (2013) Microbial esterases: an overview. International Journal of Current Microbiology and Applied Science 2(7):135–146
Scholante Delabary G, da Silva MC, da Silva CS, Baratieri LZ, de Melo TM, Stramosk CA, de Souza Lima AO, da Silva MAC (2020) Influence of temperature and culture media on growth and lipolytic activity of deep-sea Halomonas sulfidaeris LAMA 838 and Marinobacter excellens LAMA 842. Ocean and Coastal Research 68:2675–2824
Shelley AW, Deeth HC, MacRae IC (1987) Review of methods of enumeration, detection and isolation of lipolytic microorganisms with special reference to dairy applications. J Microbiol Methods 6(3):123–137
Snajdr PBJ (2007) Temperature effects the production, activity and stability of ligninolytic enzymes in Pleurotus ostreatus and Trametes versicolor. Folia Microbiol 52:498–502
Stuer W, Jaeger KE, Winkler U (1986) Purification of extracellular lipase from Pseudomonas aeruginosa. Journal of Bacteriology 168(3):1070–1074
Suresh R, Pandiaraj M, Sankaralingam M, Giribabu K (2019) Graphene–metal chalcogenide modified electrochemical sensors. In: Graphene-based electrochemical sensors for biomolecules. Elsevier, New Delhi, India, pp 139–153
Thompson TE (2021) Lipid. Encyclopaedia Britannica, Virginia, United States. Retrieved 5 September 2020, from https://www.britannica.com/science/lipid
Tsouko E, Papanikolaou S, Koutinas AA (2016) Production of fuels from microbial oil using oleaginous microorganisms. In: Luque R, Lin CSK, Wilson K, Clark J (eds) Handbook of biofuels production. Woodhead Publishing, Amsterdam Netherlands, pp 201–236
Ur Rahman U, Khan MI, Sohaib M, Sahar A, Ishaq A (2016) Exploiting microorganisms to develop improved functional meat sausages: a review. Food Rev Intl 33(2):195–215
Urbanek AK, MiroĹ„czuk AM, GarcĂa-MartĂn A, Saborido A, de la Mata I, Arroyo M (2019) Biochemical properties and biotechnological applications of microbial enzymes involved in the degradation of polyester-type plastics. Proteins and Proteonics 1868(2):140315
Wang X (2004) Lipid signaling. Curr Opin Plant Biol 39(7):329–336
Wiseman A (1977) Handbook of enzyme biotechnology: edited by Alan Wiseman. Ellis Horwood Ltd., Chichester
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Bustamante-Torres, M., Romero-Fierro, D., Estrella-Nuñez, J., Bucio, E. (2021). Microbial Degradation of Lipids. In: Inamuddin, .., Ahamed, M.I., Prasad, R. (eds) Recent Advances in Microbial Degradation. Environmental and Microbial Biotechnology. Springer, Singapore. https://doi.org/10.1007/978-981-16-0518-5_9
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