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Preoperative Assessment and Optimization of the Cancer Patient for Onco-Surgery

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Textbook of Onco-Anesthesiology

Abstract

The onco-surgical interventions require a thorough preoperative assessment that includes the global assessment of the cancer patient, focusing on their past medical and surgical history as well as their oncological history and neoadjuvant therapies. Chemotherapy and radiation therapy have important acute and chronic side effects that must be appreciated before anesthesia. Risk stratification and prognostication are crucial matters to consider in preparation of the patient for anesthesia and onco-surgery. Prehabilitation is an emerging concept for patients undergoing surgical interventions and there is some evidence that addressing modifiable risk factors may affect treatment outcomes. The prehabilitation goal is primarily to increase the physiological reserves to tolerate the stress of the perioperative period better. The impact of various prehabilitative aspects needs to be researched further in specific surgical interventions. Various testing need to be individualized. In high-risk surgical interventions, newer assessment modalities like cardiopulmonary exercise testing provide a holistic overview of cardiorespiratory function and can detect clinically occult heart disease. Further research is needed, however, before this expensive test is more widely implemented.

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References

  1. Institute NC. Cancer Statistics National Cancer Institute 2017. Available from: https://www.cancer.gov/about-cancer/understanding/statistics.

  2. Sahai SK, Ismail H. Perioperative implications of neoadjuvant therapies and optimization strategies for cancer surgery. Curr Anesthesiol Rep 2015, 5, 305-317.

    Google Scholar 

  3. Sahai S. Perioperative assessment of the cancer patient. Best Pract Res Clin Anaesthesiol. 2013;27:465–80.

    Article  Google Scholar 

  4. Fleisher LA, Fleischmann KE, Auerbach AD, Barnason SA, Beckman JA, Bozkurt B, et al. ACC/AHA guideline on perioperative cardiovascular evaluation and managment of patients undergoing noncardiac surgery: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2014;130(24):2215–45.

    Article  Google Scholar 

  5. Khakoo AY, Yeh ETH. Therapy Insight: management of cardiovascular disease in patients with cancer and cardiac complications of cancer therapy. Nat Clin Pract Oncol. 2008;5(11):655–67.

    Article  CAS  Google Scholar 

  6. Plummer C, Henderson RD, O’Sullivan JD, Read SJ. Ischemic stroke and transient ischemic attack after head and neck radiotherapy: a review. Stroke. 2011;42(9):2410–8.

    Article  Google Scholar 

  7. Davies WAD. Risk assessment in anaesthesia. Anaesthesia Intens Care Med. 2013;14:434–9.

    Article  Google Scholar 

  8. Anesthesiologists ASo. The ASA Physical Status Classification System American Society of Anesthesiologists Website2014 [cited 2014]. Available from: http://www.asahq.org/quality-and-practice-management/standards-guidelines-and-related-resources/asa-physical-status-classification-system.

  9. Surgeons ACo. The ACS NSQIP Surgical Risk Calculator Website2017. Available from: https://riskcalculator.facs.org/RiskCalculator/Index.jsp.

  10. Wijeysundera DN, et al. Measurement of Exercise Tolerance before Surgery (METS) study: a protocol for an international multicentre prospective cohort study of cardiopulmonary exercise testing prior to major non-cardiac surgery. BMJ Open. 2016;e010359:6.

    Google Scholar 

  11. Wagner D, DeMarco M, Amini N, Buttner S, Segev D, Gani F, Pawlik T. Role of frailty and sarcopenia in predicting outcomes among patients undergoing gastrointestinal surgery. World J Gastrointest Surg. 2016;8(1):27–40.

    Article  Google Scholar 

  12. Xue Q. The frailty syndrome: definition and natural history. Clin Geriatr Med. 2011;27(1):1–15.

    Article  CAS  Google Scholar 

  13. Carli F, Gillis C, Scheede-Bergdahl C. Promoting a culture of prehabilitation for the surgical cancer patient. Acta Oncol. 2017;56(2):128–33.

    Article  Google Scholar 

  14. Silver JK, Baima J. Cancer prehabilitation: an opportunity to decrease treatment-related morbidity, increase cancer treatment options, and improve physical and psychological health outcomes. Am J Phys Med Rehabil. 2013;92(8):715–27.

    Article  Google Scholar 

  15. Wilson RJ, Davies S, Yates D, Redman J, Stone M. Impaired functional capacity is associated with all-cause mortality after major elective intra-abdominal surgery. Br J Anaesth. 2010;105(3):297–303.

    Article  CAS  Google Scholar 

  16. Treanor C, Kyaw T, Donnelly M. An international review and meta-analysis of prehabilitation compared to usual care for cancer patients. J Cancer Surviv. 2018;12(1):64–73.

    Article  CAS  Google Scholar 

  17. Jones LW, Alfano CM. Exercise-oncology research: past, present, and future. Acta Oncol. 2013;52(2):195–215.

    Article  Google Scholar 

  18. Carli F, Silver JK, Feldman LS, McKee A, Gilman S, Gillis C, et al. Surgical prehabilitation in patients with cancer: state-of-the-science and recommendations for future research from a panel of subject matter experts. Phys Med Rehabil Clin N Am. 2017;28(1):49–64.

    Article  Google Scholar 

  19. Vigano A, Kasvis P, Di Tomasso J, Gillis C, Kilgour R, Carli F. Pearls of optimizing nutrition and physical performance of older adults undergoing cancer therapy. J Geriatr Oncol. 2017;8(6):428–36.

    Article  Google Scholar 

  20. Ludwig H, Van Belle S, Barrett-Lee P, Birgegard G, Bokemeyer C, Gascon P, et al. The European Cancer Anaemia Survey (ECAS): a large, multinational, prospective survey defining the prevalence, incidence, and treatment of anaemia in cancer patients. Eur J Cancer. 2004;40(15):2293–306.

    Article  Google Scholar 

  21. Munoz M, Gomez-Ramirez S, Martin-Montanez E, Auerbach M. Perioperative anemia management in colorectal cancer patients: a pragmatic approach. World J Gastroenterol. 2014;20(8):1972–85.

    Article  CAS  Google Scholar 

  22. Acheson AG, Brookes MJ, Spahn DR. Effects of allogeneic red blood cell transfusions on clinical outcomes in patients undergoing colorectal cancer surgery: a systematic review and meta-analysis. Ann Surg. 2012;256(2):235–44.

    Article  Google Scholar 

  23. Tonia T, Mettler A, Robert N, Schwarzer G, Seidenfeld J, Weingart O, et al. Erythropoietin or darbepoetin for patients with cancer. Cochrane Database Syst Rev. 2012;12:CD003407.

    PubMed  Google Scholar 

  24. Gajdos C, Hawn MT, Campagna EJ, Henderson WG, Singh JA, Houston T. Adverse effects of smoking on postoperative outcomes in cancer patients. Ann Surg Oncol. 2012;19(5):1430–8.

    Article  Google Scholar 

  25. Moller AM, Villebro N, Pedersen T, Tonnesen H. Effect of preoperative smoking intervention on postoperative complications: a randomised clinical trial. Lancet (London, England). 2002;359(9301):114–7.

    Article  Google Scholar 

  26. Tonnesen H, Faurschou P, Ralov H, Molgaard-Nielsen D, Thomas G, Backer V. Risk reduction before surgery. The role of the primary care provider in preoperative smoking and alcohol cessation. BMC Health Serv Res. 2010;10:121.

    Article  Google Scholar 

  27. Yoshida N, Baba Y, Hiyoshi Y, Shigaki H, Kurashige J, Sakamoto Y, et al. Duration of smoking cessation and postoperative morbidity after esophagectomy for esophageal cancer: how long should patients stop smoking before surgery? World J Surg. 2016;40(1):142–7.

    Article  Google Scholar 

  28. Yoshida N, Nakamura K, Kuroda D, Baba Y, Miyamoto Y, Iwatsuki M, et al. Preoperative smoking cessation is integral to the prevention of postoperative morbidities in minimally invasive esophagectomy. World J Surg. 2018 42(9):2902-2909.

    Google Scholar 

  29. Bradt J, Dileo C, Shim M. Music interventions for preoperative anxiety. Cochrane Database Syst Rev. 2013;6:CD006908.

    Google Scholar 

  30. Moran J, Wilson F, Guinan E, McCormick P, Hussey J, Moriarty J. Role of cardiopulmonary exercise testing as a risk-assessment method in patients undergoing intra-abdominal surgery: a systematic review. Br J Anaesth. 2016;116(2):177–91.

    Article  CAS  Google Scholar 

  31. American Thoracic S, American College of Chest P. ATS/ACCP Statement on cardiopulmonary exercise testing. Am J Respir Crit Care Med 2003;167(2):211–277.

    Google Scholar 

  32. Albouaini K, Egred M, Alahmar A, Wright DJ. Cardiopulmonary exercise testing and its application. Postgrad Med J. 2007;83(985):675–82.

    Article  Google Scholar 

  33. Levett DZ, Grocott MP. Cardiopulmonary exercise testing for risk prediction in major abdominal surgery. Anesthesiol Clin. 2015;33(1):1–16.

    Article  Google Scholar 

  34. Hennis PJ, Meale PM, Grocott MP. Cardiopulmonary exercise testing for the evaluation of perioperative risk in non-cardiopulmonary surgery. Postgrad Med J. 2011;87(1030):550–7.

    Article  Google Scholar 

  35. Wijeysundera DN, Pearse RM, Shulman MA, Abbott TE, Torres E, Croal BL, et al. Measurement of Exercise Tolerance before Surgery (METS) study: a protocol for an international multicentre prospective cohort study of cardiopulmonary exercise testing prior to major non-cardiac surgery. BMJ Open. 2016;6(3):e010359.

    Article  Google Scholar 

  36. Richardson K, Levett DZH, Jack S, Grocott MPW. Fit for surgery? Perspectives on preoperative exercise testing and training. Br J Anaesth. 2017;119(suppl_1):i34–43.

    Article  CAS  Google Scholar 

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Correspondence to Shannon M. Popovich .

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Nguyen, L.T., Popovich, S.M. (2021). Preoperative Assessment and Optimization of the Cancer Patient for Onco-Surgery. In: Garg, R., Bhatnagar, S. (eds) Textbook of Onco-Anesthesiology. Springer, Singapore. https://doi.org/10.1007/978-981-16-0006-7_5

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  • DOI: https://doi.org/10.1007/978-981-16-0006-7_5

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