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Nanothermometry for Deep Tissues by Using Near-Infrared Fluorophores

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Transparency in Biology

Abstract

Temperature is a fundamental quantity that can regulate various biological phenomena and thus important in clinical biology as well as sport and health sciences. This chapter reviews how the body temperature is regulated in the organisms (mainly in mammals including humans), and how the body temperature of not only the surface but also the deep tissues. As an emerging technique, the luminescence nanothermometry that works in the over-thousand-nanometer (OTN) near-infrared (NIR) wavelength range, which allows us to look the biological tissues transparently, is being developed to visualize and reveal the mechanisms of dynamic time-dependent changes in body temperature distribution in deep tissues. The data and knowledge collected with the new techniques will provide insights into body temperature control in biology and its management in biomedical and engineering fields.

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Authors and Affiliations

  1. Department of Materials Science and Technology, Faculty of Industrial Science and Technology, Tokyo University of Science, 6-3-1 Niijuku, Katsushika, Tokyo, 125-8585, Japan

    Masakazu Umezawa & Karina Nigoghossian

  2. ICGM, Univ. Montpellier, CNRS, ENSCM, UM, Bât 17, cc1701, Place Eugène Bataillon, 34095, Montpellier, France

    Karina Nigoghossian

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  1. Masakazu Umezawa
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  2. Karina Nigoghossian
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Correspondence to Masakazu Umezawa .

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  1. Materials Science and Technology, Tokyo University of Science, Tokyo, Japan

    Kohei Soga

  2. Materials Science and Technology, Tokyo University of Science, Tokyo, Japan

    Masakazu Umezawa

  3. Materials Science and Technology, Tokyo University of Science, Tokyo, Japan

    Kyohei Okubo

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Umezawa, M., Nigoghossian, K. (2021). Nanothermometry for Deep Tissues by Using Near-Infrared Fluorophores. In: Soga, K., Umezawa, M., Okubo, K. (eds) Transparency in Biology. Springer, Singapore. https://doi.org/10.1007/978-981-15-9627-8_7

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