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Metabolomics and Its Applications to Personalized Medicine

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Abstract

The basis of this review is to evaluate the field of metabolomics. The strategies used in this field will be explored to understand the process of biomarker discovery, especially those with clinical value, giving rise to personalized medicine. Metabolomics is the process of profiling metabolites in a biological system, due to this it has significant potential in decoding the ultimate product of the genomic processes. It is becoming increasingly clear that the field has possible limitations that is resolved by a potential metabolomic assay that has the ability to directly target a selection of metabolites combating the issue of variability amongst samples and allow for reproducible data. Recently, an increased effort has been made to formulate a universally accepted approach. Enabling the field to progress into to a more clinical-based setting. Diseases in a biological system tend to have a “signature” of sorts: a fluctuating metabolite profile is a representation of cellular activity. Monitoring such fluctuations allows for health care that accounts for external factors such as (i) lifestyle, (ii) environmental factors and (iii) genetic information in advance of treatment.

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Authors and Affiliations

  1. Trinity Biomedical Sciences Institute (TBSI), School of Biochemistry & Immunology, Trinity College Dublin, The University of Dublin, Dublin 2, Ireland

    Lee Sherlock & K. H. Mok

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  1. Lee Sherlock
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  2. K. H. Mok
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Correspondence to K. H. Mok .

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Editors and Affiliations

  1. ams AG, Premstaetten, Austria

    Jong Mun Park

  2. Department of Advanced Materials, Hannam University, Daejeon, Korea (Republic of)

    Dong Ryeol Whang

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Sherlock, L., Mok, K.H. (2021). Metabolomics and Its Applications to Personalized Medicine. In: Park, J.M., Whang, D.R. (eds) EKC 2019 Conference Proceedings. EKC 2019. Springer, Singapore. https://doi.org/10.1007/978-981-15-8350-6_3

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  • DOI: https://doi.org/10.1007/978-981-15-8350-6_3

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