Skip to main content

Acute Pain management in Onco Surgical Patient: Overview

  • Chapter
  • First Online:
Multidisciplinary Approach to Surgical Oncology Patients

Abstract

Pain is a complex multifactorial phenomenon which has a biological basis, huge psychological component, and a great social impact (Biopsychosocial model of pain) [60]. Broadly speaking pain can be classified into three broad categories—acute pain, that is the pain immediately following an operation or injury so it has an identifiable temporal and causal relationship to injury or disease, cancer pain which happens due to metastasis, invasion of tissues or inflammation from cancer and the third type of pain is chronic non-malignant pain like headache, backache, fibromyalgia or neuropathic pain. Chronic pain usually starts after tissue healing often without any specific identifiable cause in most cases persists beyond 3 months of the initial injury. Many scholars present a view that is acute and chronic pain may represent a continuum rather than distinct entities. In this chapter, we will limit ourselves to the definition of pain, the pathophysiology of acute postoperative pain, the assessment of the patients in pain, management of the postoperative patients and some challenges you will face in the ward. The aim of this chapter is not to impede the freedom of the clinician but to provide him with guidance to form a robust, evidence-based and acceptable working protocol. It will help the clinical staff to manage patient more proficiently and establish standardized care which can be audited against a standard to improvise and compare the outcome.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Turk DC, Monarch ES. Biopsychosocial perspective on chronic pain. In: Turk DC, Gatchel RJ, editors. Psychological approaches to pain management. 2nd ed. New York: Guildford Press; 1995.

    Google Scholar 

  2. Merskey H, Bogduk N. Classification of chronic pain, IASP Task Force on Taxonomy. Seattle: IASP Press; 1994.

    Google Scholar 

  3. Pincus T, Vlaeyen JW, Kendall NA, et al. Cognitive-behavioral therapy and psychosocial factors in low back pain: directions for the future. Spine. 2002;27(5):E133–8.

    Article  PubMed  Google Scholar 

  4. Bullingham A, Strunin L. Prevention of postoperative venous thromboembolism. Br J Anaesth. 1995;75:622–30.

    Article  CAS  PubMed  Google Scholar 

  5. Carr ECJ, Thomas VN, Wilson-Barnet J. Patient experiences of anxiety, depression and acute pain after surgery: a longitudinal perspective. Int J Nurs Stud. 2005;42(5):521–30.

    Article  PubMed  Google Scholar 

  6. Krenk L, Rasmussen LS, Kehlet H. New insights into the pathophysiology of postoperative cognitive dysfunction. Acta Anaesthesiol Scand. 2010;54:951–6.

    Article  CAS  PubMed  Google Scholar 

  7. Woolf CJ, Ma Q. Nociceptors–noxious stimulus detectors. Neuron. 2007;55(3):353–64.

    Article  CAS  PubMed  Google Scholar 

  8. Wall. The gate control theory of pain mechanisms - a re-examination and re-statement. Brain. 1978;101:1–18.

    Article  CAS  PubMed  Google Scholar 

  9. www.nes.scot.nhs.uk/media/2701203/faces_scale_tool.pdf

  10. Pierre S, Whelan R. Nausea and vomiting after surgery. BJA. http://ceaccp.oxfordjournals.org/content/early/2012/08/10/bjaceaccp.mks046.full.pdf+html

  11. Apfel CC, Korttila K, Abdalla M, et al. A factorial trial of six interventions for the prevention of postoperative nausea and vomiting. N Engl J Med. 2004;350:2441–51.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Pasero C, McCaffery M. Monitoring opioid-induced sedation. Am J Nurs. 2002;102:67–8.

    Article  PubMed  Google Scholar 

  13. Pasero C, McCaffery M. Safe use of continuous infusion with IV PCA. J Perianesth Nurs. 2004;19:42–5.

    Article  PubMed  Google Scholar 

  14. Cazacu I, Mogosan C, Loghin F. Safety issues of current analgesics: an update. Clujul Med. 2015;88(2):128–36.

    PubMed  PubMed Central  Google Scholar 

  15. KeõÈta H, Geachan N, Dahmani S, Couderc E, Armand C, Quazza M, Mantz J, Desmonts JM. Comparison between patient-controlled analgesia and subcutaneous morphine in elderly patients after total hip replacement. Br J Anaesth. 2003;90(1):53.

    Article  CAS  Google Scholar 

  16. https://www.evidence.nhs.uk/formulary/bnf/current/guidance-on-prescribing/prescribing-in-palliative-care/pain/pain-management-with-opioids

  17. McQuay H. Opioids in pain management. The Lancet. June 1999;353(9171):2229–32.

    Article  CAS  Google Scholar 

  18. Minami K, Ogata J, Uezono Y. What is the main mechanism of tramadol? Naunyn Schmiedebergs Arch Pharmacol. 2015 Oct;388(10):999–1007.

    Article  CAS  PubMed  Google Scholar 

  19. Frampton JE. Tapentadol immediate release: a review of its use in the treatment of moderate to severe acute pain. Drugs. 2010 Sep 10;70(13):1719–43.

    Article  CAS  PubMed  Google Scholar 

  20. Candiotti KA, Gitlin MC. Review of the effect of opioid-related side effects on the undertreatment of moderate to severe chronic non-cancer pain: tapentadol, a step toward a solution? Curr Med Res Opin. 2010 Jul;26(7):1677–84.

    Article  CAS  PubMed  Google Scholar 

  21. Wiffen PJ. Systematic reviews published in the July 2015 issue of the Cochrane Library. J Pain Palliat Care Pharmacother. 2015 Dec;29(4):416–8.

    Article  Google Scholar 

  22. Baxter G, Morgan CL, Jenkins-Jones S, Currie CJ, Schultewolter D. Association of adverse events and health service usage with tapentadol prolonged-release treatment compared with morphine controlled-release (Cr) and oxycodone Cr: a UK Primary Care Observational Study. Value Health. 2015 Nov;18(7):A658.

    Article  Google Scholar 

  23. Mofizul Islam M, McRae IS, Mazumdar S, Taplin S, McKetin R. Prescription opioid analgesics for pain management in Australia: twenty years of dispensing. Int Med J. 2015 Nov;25

    Google Scholar 

  24. Jadad AR, Browman GP. The WHO analgesic ladder for cancer pain management. Stepping up the quality of its evaluation. JAMA. 1995;274(23):1870–3.

    Article  CAS  PubMed  Google Scholar 

  25. Vadalouca A, Moka E, Argyra E, Sikioti P, Siafaka I. Opioid rotation in patients with cancer: a review of the literature. J Opioid Manag. 2008;4(4):213–50.

    Article  PubMed  Google Scholar 

  26. Bauer M, George JE III, Seif J, Farag E. Recent advances in epidural analgesia. Anesthesiol Res Pract. 2012;309219:2012.

    Google Scholar 

  27. https://www.saskatoonhealthregion.ca/about/NursingManual/1080.pdf

  28. Regional anesthesia in the anticoagulated patient: defining the risks (The second ASRA Consensus Conference on neuraxial anesthesia and anticoagulation). Reg Anesth Pain Med 28(3): 172–197; May-June 2003.

    Google Scholar 

  29. Barbara L, Buchko DNP, Robinson LE. An evidence-based approach to decrease early post-operative urinary retention following urogynecologic surgery. Urol Nurs. 2012;32(5):260–4.

    Article  Google Scholar 

  30. Swegle OM, Logemann C. Management of common opioid-induced adverse effects. Am Fam Phys. 2006 Oct 15;74(8):1347–54.

    Google Scholar 

  31. Kumar K, Singh SI. Neuraxial opioid-induced pruritus: an update. J Anaesthesiol Clin Pharmacol. 2013;29(3):303–7.

    Article  PubMed  PubMed Central  Google Scholar 

  32. Glenn E, Mehl J, Rosinia FA, Liu H. Safe removal of an epidural catheter 72 hours after clopidogrel and aspirin administrations guided by platelet function analysis and thromboelastography. J Anaesthesiol Clin Pharmacol. 2013 Jan-Mar;29(1):99–101.

    Article  PubMed  PubMed Central  Google Scholar 

  33. Vela Vásquez RS, Peláez Romero R. Aspirin and spinal haematoma after neuraxial anaesthesia: myth or reality? Br J Anaesth. 2015 Nov;115(5):688–98.

    Article  PubMed  CAS  Google Scholar 

  34. Eipe N, Penning J, Yazdi F, Mallick R, Turner L, Ahmadzai N, Ansari MT. Perioperative use of pregabalin for acute pain—a systematic review and meta-analysis. Pain. 2015;156:1284–300.

    Article  PubMed  Google Scholar 

  35. Kehlet H, Jensen TS, Woolf CJ. Persistent postsurgical pain: risk factors and prevention. Lancet. 2006;367(9522):1618–25.

    Article  PubMed  Google Scholar 

  36. Ong CK, Lirk P, Seymour RA, et al. The efficacy of preemptive analgesia for acute postoperative pain management: a meta-analysis. Anesth Analg. 2005;100(3):757–73.

    Article  PubMed  Google Scholar 

  37. Nikolajsen L, Ilkjaer S, Christensen JH, Krøner K, Troels S, Jensen M. Randomised trial of epidural bupivacaine and morphine in prevention of stump and phantom pain in lower-limb amputation. The Lancet. 8 Nov 1997;350(9088):1353–7.

    Article  CAS  Google Scholar 

  38. Fisher A, Meller Y. Continuous postoperative regional analgesia by nerve sheath block for amputation surgery-a pilot study. Anesth Analg. 1991;72:30–3.

    Article  Google Scholar 

  39. Lambert AW, Dashfield AK, Cosgrove C, Wilkins DC, Walker AJ, Ashley S. Randomized prospective study comparing preoperative epidural and intraoperative perineural analgesia for the prevention of postoperative stump and phantom limb pain following major amputation. Reg Anesth Pain Med. July 2001;26(4):316–21.

    Article  Google Scholar 

  40. Portenoy RK, Foley KM. Chronic use of opioid analgesics in non-malignant pain: Report of 38 cases. Pain. May 1986;25(2):171–86.

    Article  PubMed  Google Scholar 

  41. Robinson TE, Berridge KC. The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Res Rev. Sept–Dec 1993;18(3):247–91.

    Article  CAS  PubMed  Google Scholar 

  42. Rat P, Jouve E, Pickering G, Donnarel L, Nguyen L, Michel M, Capriz-Ribière F, Lefebvre-Chapiro S, Gauquelin F, Bonin-Guillaume S. Validation of an acute pain-behavior scale for older persons with inability to communicate verbally: Algoplus. Eur J Pain. 2011 Feb;15(2):198.e1–198.e10.

    Article  Google Scholar 

  43. Bernabei R, et al. Management of pain in elderly patients with cancer. SAGE Study Group. Systematic assessment of geriatric drug use via epidemiology. JAMA. 1998;279:1877–82.

    Article  CAS  PubMed  Google Scholar 

  44. Sophie Pautex FR, Herrmann PLL, Gold G. Improving pain management in elderly patients with dementia: validation of the Doloshort observational pain assessment scale. Age Ageing. 2009:1–4.

    Google Scholar 

  45. Hand CW, Sear JW, Uppington J, Ball MJ, McQuay HJ, Moore RA. Buprenorphine disposition in patients with renal impairment: single and continuous dosing, with special reference to metabolites. Br J Aneasth. 1990;64(3):276–82.

    Article  CAS  Google Scholar 

  46. Vadivelu N, Huang Y, Mirante B, Jacoby M, Braveman FR, Hines RL, Sinatra R. Patient considerations in the use of tapentadol for moderate to severe pain. Drug Healthc Patient Saf. 2013;5:151–9.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  47. Xu S, Smit JW, Lin R, Stuyckens K, Terlinden R, Nandy P. Population pharmacokinetics of tapentadol immediate release (IR) in healthy subjects and patients with moderate or severe pain. Clin Pharmacokin Oct. 2010;49(10):671–82.

    Article  CAS  Google Scholar 

  48. Conway BR, Fogarty DG, Nelson WE, Doherty CC. Opiate toxicity in patients with renal failure. BMJ. 2006;332:345–6.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2021 Springer Nature Singapore Pte Ltd.

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Bagchi, S. (2021). Acute Pain management in Onco Surgical Patient: Overview. In: Ray, M.D. (eds) Multidisciplinary Approach to Surgical Oncology Patients. Springer, Singapore. https://doi.org/10.1007/978-981-15-7699-7_10

Download citation

  • DOI: https://doi.org/10.1007/978-981-15-7699-7_10

  • Published:

  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-15-7698-0

  • Online ISBN: 978-981-15-7699-7

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics