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Unique Properties of the Gold Nanoparticles: Synthesis, Functionalization and Applications

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Application of Nanotechnology in Biomedical Sciences

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Abstract

The application of nanotechnology in current years has been explored to a greater extent in the different biomedical applications. Among the metal-based nanoparticles (NPs), especially the gold (Au), have been employed in therapeutics, colorimetric assays and, imaging applications. Because of the surface plasmon resonance of Au NPs, these NPs represent a unique optical and electrochemical properties. They are considered as highly compatible owing to their inert nature in the biological domain. Due to the recent advances in synthetic chemistry, researchers have explored different routes for synthesizing the Au NPs with the intension to have the desired size and to create NPs with different morphology. Moreover, the large surface to volume ratio of the NPs allows usefulness concerning the functionalization with bioactive molecules and fluorescent probes. Overall, this chapter highlights the synthesis of Au NPs, functionalization and their properties in different biomedical applications. In brief, a comprehensive account of applications in targeted delivery (e.g., in gene and/or drug), therapeutic such as immunotherapy, bio-imaging, colorimetric assays/bio-sensing are discussed.

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Acknowledgments

We thank the Science and Engineering Research Board (SERB) research grants (ECR/2016/001429) for providing lab funds and supporting the fellow.

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Authors and Affiliations

  1. Department of Nanotechnology, University of Kashmir, Srinagar, Jammu and Kashmir, India

    Roqia Ashraf & Faheem A. Sheikh

  2. Department of Biology, Faculty of Science, Albaha University, Al Bahah, Kingdom of Saudi Arabia

    Touseef Amna

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  1. Roqia Ashraf
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  2. Touseef Amna
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  3. Faheem A. Sheikh
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Correspondence to Faheem A. Sheikh .

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  1. Department of Nanotechnology, University of Kashmir, Srinagar, Jammu and Kashmir, India

    Faheem A. Sheikh

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Ashraf, R., Amna, T., Sheikh, F.A. (2020). Unique Properties of the Gold Nanoparticles: Synthesis, Functionalization and Applications. In: Sheikh, F. (eds) Application of Nanotechnology in Biomedical Sciences. Springer, Singapore. https://doi.org/10.1007/978-981-15-5622-7_5

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