Abstract
Microalgae can provide a platform technology to synthetic biologists for the production of pharmaceutical biocommodities. Based on their diversity, the main pathways for a range of plant-derived compounds are innately present across the multiple phyla of microalgae. Current efforts focus primarily on overexpression of genes involved with lipid biosynthesis but the doors are opening for a whole range of therapeutics, including pigments, terpenes, recombinant proteins, and RNAi products. A variety of open source tools are expanding into the academic space for a whole range of molecular tasks. This chapter focusses on heterologous photoautotrophic production of pharmaceuticals in microalgae.
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Brown, R.B., Wass, T.J., Schenk, P.M. (2020). Synthetic Biology Tools for Microalgae. In: Nathani, N.M., Mootapally, C., Gadhvi, I.R., Maitreya, B., Joshi, C.G. (eds) Marine Niche: Applications in Pharmaceutical Sciences . Springer, Singapore. https://doi.org/10.1007/978-981-15-5017-1_13
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DOI: https://doi.org/10.1007/978-981-15-5017-1_13
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