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Immunotoxicity of Nanoparticles

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Allergy and Immunotoxicology in Occupational Health - The Next Step

Abstract

In this chapter, we review the latest and main research findings on anthropic nanoparticles (NPs) from the immune-cytotoxicological perspective aiming at defining the intrinsic chemical-physical and the extrinsic (acquired by the interaction with the environment) characteristics of the nano-systems to which the immune system appears to be unresponsive, tolerant, or anergic. The hereby outlined presumptive and speculative determinants of immune compatibility of nanoparticulate matters, although based on experimental data, represent a basic information for the design of new biocompatible nanomatters; finally, they represent an evaluation tool for potential immune outcome in professionally involved workers and may be important to enhance the exertion of risk assessment.

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Author information

Authors and Affiliations

  1. Unit of Immunotoxicology and Allergy, Department of Medicine and Aging Sciences (DMSI) and CAST, University G. d’Annunzio of Chieti-Pescara, Chieti, Italy

    Claudia Petrarca

  2. Prevention and Protection Service, University Chieti-Pescara, Pescara, Italy

    Rocco Mangifesta

  3. Department of Oral, Biotechnological and Medical Sciences, University Chieti-Pescara, Pescara, Italy

    Luca Di Giampaolo

Authors
  1. Claudia Petrarca
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  2. Rocco Mangifesta
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  3. Luca Di Giampaolo
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Correspondence to Claudia Petrarca .

Editor information

Editors and Affiliations

  1. Department of Hygiene, Kawasaki Medical School, Kurashiki, Okayama, Japan

    Takemi Otsuki

  2. Department of Medicine and Aging Science (DMSI), University G. d’Annunzio of Chieti-Pescara, Chieti, Italy

    Mario Di Gioacchino

  3. Department of Medicine and Aging Science (DMSI), University G. d’Annunzio of Chieti-Pescara, Chieti, Italy

    Claudia Petrarca

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Petrarca, C., Mangifesta, R., Di Giampaolo, L. (2020). Immunotoxicity of Nanoparticles. In: Otsuki, T., Di Gioacchino, M., Petrarca, C. (eds) Allergy and Immunotoxicology in Occupational Health - The Next Step. Current Topics in Environmental Health and Preventive Medicine. Springer, Singapore. https://doi.org/10.1007/978-981-15-4735-5_6

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  • DOI: https://doi.org/10.1007/978-981-15-4735-5_6

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