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ICSI: Yesterday, Today, and Tomorrow

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Textbook of Assisted Reproduction

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Abstract

Over the past 20 years, intracytoplasmic sperm injection (ICSI) has become a staple technique in the human-assisted reproduction laboratory and helped facilitate the birth of millions of healthy children for couples who in many cases had no other reproductive options. We will examine the history behind the development of the technique from animal research and early human-assisted fertilization protocols. ICSI application has exhibited great expansion in laboratory practices and modalities and now provides successful treatment options for essentially every aspect of male factor infertility. Meanwhile, the application of ICSI has expanded outside of the clinical treatment of male factor patients. This has been subject to some criticism which will be discussed along with a long history of general follow-up studies on ICSI offspring. Finally, the technique will no doubt see changes in the future including improvements and expanded utility in non-fertilization-related aspects.

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Authors and Affiliations

  1. Fertility Center of the Carolinas, University of South Carolina School of Medicine, Greenville, SC, USA

    Henry E. Malter

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  1. Henry E. Malter
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Correspondence to Henry E. Malter .

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Editors and Affiliations

  1. Consultant Reproductive Endocrinology & IVF Millennium Medical Center MMC IVF, Dubai Health Care City, Dubai, United Arab Emirates

    Gautam Nand Allahbadia

  2. Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Koç University School of Medicine, Istanbul, Turkey

    Baris Ata

  3. Department of Obstetrics and Gynecology, Wright State University, Boonshoft School of Medicine, Dayton, OH, USA

    Steven R. Lindheim

  4. X&Y Fertility, Leicester, UK

    Bryan J. Woodward

  5. School of Medicine and Dentistry, University of Rochester Medical Center, Newyork, USA

    Bala Bhagavath

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Malter, H.E. (2020). ICSI: Yesterday, Today, and Tomorrow. In: Allahbadia, G.N., Ata, B., Lindheim, S.R., Woodward, B.J., Bhagavath, B. (eds) Textbook of Assisted Reproduction. Springer, Singapore. https://doi.org/10.1007/978-981-15-2377-9_87

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  • DOI: https://doi.org/10.1007/978-981-15-2377-9_87

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