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Bioactive Potentials of Novel Molecules from the Endophytes of Medicinal Plants

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Medically Important Plant Biomes: Source of Secondary Metabolites

Part of the book series: Microorganisms for Sustainability ((MICRO,volume 15))

Abstract

Microbial endophytes have a long-standing association with numerous plant species. A closer look into their diversity indicates the existence of novel species from biologically diverse regions on the earth, especially the tropics. The novelty is related to their ability to produce diverse chemical structures with reliable bioactive potentials, which has resulted in the addition of new compounds to the unending list of natural products. Hyphenated techniques have fastened the cumbersome screening of crude extracts with reliable bioassays resulting in the elucidation of novel compounds or molecules of interest. Biotechnological approaches are of added advantage in the production of such compounds with remarkable bioactivities. This chapter highlights the fungi and actinomycetes as endophytes from the medicinal and pharmaceutical plants of relevance, host-related metabolites, novel bioactive metabolites of endophytes, and approaches for the augmentation of metabolites and a special mention of the metabolites by Pestalotiopsis species. Therefore, endophytes are microbial chemical factories more suited for the production of novel metabolites with therapeutic potentials.

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Acknowledgments

The authors wish to thank Dr. Dilfuza Egamberdieva, Institute of Landscape Biogeochemistry, Germany, for the invite to compile the book chapter. The timely help of research students is gratefully acknowledged.

Conflict of Interest

The authors declare that there is no conflict of interest involved in this study.

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Authors and Affiliations

  1. Department of Studies in Botany, University of Mysore, Mysore, Karnataka, India

    Monnanda S. Nalini

  2. Department of Studies in Biotechnology, University of Mysore, Mysore, Karnataka, India

    Harischandra S. Prakash

  3. Department of Ecology & Genetics, University of Oulu, Oulu, Finland

    Mysore V. Tejesvi

  4. Chain Antimicrobials Ltd., Oulu, Finland

    Mysore V. Tejesvi

Authors
  1. Monnanda S. Nalini
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  2. Harischandra S. Prakash
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  3. Mysore V. Tejesvi
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Editors and Affiliations

  1. Faculty of Biology, National University of Uzbekistan, Tashkent, Uzbekistan

    Dilfuza Egamberdieva

  2. Department for the Innovation on Biological, Agrofood and Forestal systems (DIBAF), Laboratoy of Plant Cytology and Biotechnology, Tuscia University, Viterbo, Vatican City State

    Antonio Tiezzi

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Nalini, M.S., Prakash, H.S., Tejesvi, M.V. (2019). Bioactive Potentials of Novel Molecules from the Endophytes of Medicinal Plants. In: Egamberdieva, D., Tiezzi, A. (eds) Medically Important Plant Biomes: Source of Secondary Metabolites. Microorganisms for Sustainability, vol 15. Springer, Singapore. https://doi.org/10.1007/978-981-13-9566-6_13

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