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Role of TLR4 in Sepsis

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Severe Trauma and Sepsis

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Abstract

Sepsis, a syndrome of physiologic pathologic and biochemical abnormalities induced by infection, is a major public health concern. The concept of sepsis changed as time goes by. According to the Third International Consensus Definitions for Sepsis and Septic Shock, sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. So far, the number of patients suffering from sepsis has been on rise. However, the diagnosis of sepsis is still difficult.

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Authors and Affiliations

  1. Department of Anesthesia, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China

    Jing Tang

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  1. Jing Tang
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Editors and Affiliations

  1. Wound Healing and Cell Biology Lab, First Affiliated Hospital, Chinese PLA General Hospital, Beijing, China

    Xiaobing Fu

  2. State Key Laboratory of Trauma, Burns, and Combined Injury, Daping Hospital, Third Military Medical University, Chong Qing, China

    Liangming Liu

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Tang, J. (2019). Role of TLR4 in Sepsis. In: Fu, X., Liu, L. (eds) Severe Trauma and Sepsis. Springer, Singapore. https://doi.org/10.1007/978-981-13-3353-8_7

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  • DOI: https://doi.org/10.1007/978-981-13-3353-8_7

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