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Secondary Tumors of the Ovary

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Gynecologic and Obstetric Pathology, Volume 2

Abstract

Secondary tumors of the ovary (STO) are tumors from extraovarian sites. Determining the primary versus secondary nature of an ovarian neoplasm is an exercise that may range from simple to essentially impossible due to similarities in gross, microscopic, and clinical features of some primary and secondary ovarian tumors. Adding to the difficulty is the fact that, in some cases, the pathologist (and clinician) may be unaware of a synchronous or historical extraovarian primary neoplasm. As misdiagnosis impacts prognosis and treatment, it is important that the pathologist have an appropriate index of suspicion of metastasis, and a grasp of the possible gross, microscopic, clinical, and immunohistochemical staining features of secondary ovarian tumors. Tumors metastatic to the ovary may originate from almost any primary site, especially in young females, in whom the rich vascularization of the ovaries may render them more susceptible to metastasis. As ovarian metastasis has been documented to appear many years after diagnosis, it is emphasized that a history of neoplasia of any type, even if remote, may be significant in the evaluation of an ovarian tumor with morphologic features unusual for a primary ovarian neoplasm.

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References

  1. Kubeček O, Laco J, Špaček J et al (2017) The pathogenesis, diagnosis, and management of metastatic tumors to the ovary: a comprehensive review. Clin Exp Metastasis 34:295–307

    Article  Google Scholar 

  2. Lerwill M, Young R (2011) Metastatic Tumors of the Ovary. In: Kurman R, Hedrick Ellenson L, Ronnet B (eds) Blaustein’s Pathology of the Female Genital Tract, 6th ed. Springer Science+Business Media LLC, Boston, MA, p 929–997

    Chapter  Google Scholar 

  3. Skírnisdóttir I, Garmo H, Holmberg L (2007) Non-genital tract metastases to the ovaries presented as ovarian tumors in Sweden 1990–2003: Occurrence, origin and survival compared to ovarian cancer. Gynecol Oncol 105:166–171

    Google Scholar 

  4. Moore RG, Chung M, Granai CO et al (2004) Incidence of metastasis to the ovaries from nongenital tract primary tumors. Gynecol Oncol 93:87–91

    Article  PubMed  Google Scholar 

  5. de Waal YR, Thomas CM, Oei AL et al (2009) Secondary ovarian malignancies: frequency, origin, and characteristics. Int J Gynecol Cancer 19:1160–1165

    Article  PubMed  Google Scholar 

  6. Khunamornpong S, Suprasert P, Chiangmai WN, et al (2006) Metastatic tumors to the ovaries: a study of 170 cases in northern Thailand. Int J Gynecol Cancer 16:132–8

    Article  PubMed  Google Scholar 

  7. Yada-Hashimoto N, Yamamoto T, Kamiura S, et al (2003) Metastatic ovarian tumors: a review of 64 cases. Gynecol Oncol 89:314–7

    Article  PubMed  Google Scholar 

  8. Lee SJ, Bae JH, Lee AW et al (2009) Clinical Characteristics of Metastatic Tumors to the Ovaries. J Korean Med Sci 24:114

    Article  PubMed  PubMed Central  Google Scholar 

  9. Bruls J, Simons M, Overbeek L et al (2015) A national population-based study provides insight in the origin of malignancies metastatic to the ovary. Virchows Arch 467:79–86

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Bruchim I, Ben-Harim Z, Piura E et al (2013) Preoperative clinical and radiological features of metastatic ovarian tumors. Arch Gynecol Obstet 288:615–619

    Article  PubMed  Google Scholar 

  11. Kiyokawa T, Young R, Scully R (2006) Krukenberg Tumors of the Ovary: A clinicopathologic analysis of 120 cases with emphasis on their variable pathologic manifestations. Am J Surg Pathol 30:277–299

    Article  PubMed  Google Scholar 

  12. Clement P, Young R (2014) Metastatic Tumors of the Ovary (including Pseudomyxoma Peritonei, Hematolymphoid Neoplasms, and Tumors with Functioning Stroma). In: Atlas of Gynecologic Surgical Pathology, 3rd edn. Saunders Elsevier, London, p 482–512

    Google Scholar 

  13. Ronnett B, Yemelyanova A, Vang R et al (2008) Endocervical adenocarcinomas with ovarian metastases: analysis of 29 cases with emphasis on minimally invasive cervical tumors and the ability of the metastases to simulate primary ovarian neoplasms. Am J Surg Pathol 32:1835–1853

    Article  PubMed  Google Scholar 

  14. Pins M, Young R, Crum C et al (1997) Cervical squamous cell carcinoma in situ with intraepithelial extension to the upper genital tract and invasion of tubes and ovaries. Int J Gynecol Pathol 16:272–278

    Article  CAS  PubMed  Google Scholar 

  15. Khunamornpong S, Suprasert P, Pojchamarnwiputh S et al (2006) Primary and metastatic mucinous adenocarcinomas of the ovary: evaluation of the diagnostic approach using tumor size and laterality. Gynecol Oncol 101:152–157

    Article  PubMed  Google Scholar 

  16. Seidman J, Kurman R, Ronnett B (2003) Primary and metastatic mucinous adenocarcinomas in the ovaries: incidence in routine practice with a new approach to improve intraoperative diagnosis. The American Journal of Surgical Pathology 27:985–993

    Article  PubMed  Google Scholar 

  17. Yemelyanova A, Vang R, Judson K et al (2008) Distinction of primary and metastatic mucinous tumors involving the ovary: analysis of size and laterality data by primary stage with reevaluation of an algorithm for tumor classification. Am J Surg Pathol 32:128–138

    Article  PubMed  Google Scholar 

  18. Lewis M, Deavers M, Silva E, Malpica A (2006) Ovarian involvement by metastatic colorectal carcinoma: still a diagnostic challenge. Am J Surg Pathol 30:177–184

    Article  PubMed  Google Scholar 

  19. Strickland S, Wasserman J, Giassi A et al (2016) Immunohistochemistry in the diagnosis of mucinous neoplasms involving the ovary: The added value of SATB2 and biomarker discovery through protein expression database mining. Int J Gynecol Pathol 35:191–208

    Article  CAS  PubMed  Google Scholar 

  20. Lee K, Young R (2003) The distinction between primary and metastatic mucinous carcinomas of the ovary: gross and histologic findings in 50 cases. Am J Surg Pathol 27:281–292

    Article  PubMed  Google Scholar 

  21. Moh M, Krings G, Ates D et al (2016) SATB2 expression distinguishes ovarian metastases of colorectal and appendiceal origin from primary ovarian tumors of mucinous or endometrioid type. Am J Surg Pathol 40:419–32

    Article  PubMed  Google Scholar 

  22. Krasinskas AM, Goldsmith JD (2014) Immunohistology of the Gastrointestinal Tract. In: Dabbs DJ (ed) Diagnostic Immunohistochemistry: Theranostic and Genomic Applications. 4th edn. Saunders Elsevier, Philadelphia, p 508–539

    Google Scholar 

  23. Rabban JT, Longacre TA (2014) Immunohistology of the female genital tract. In: Dabbs DJ (ed) Diagnostic Immunohistochemistry: Theranostic and Genomic Applications. 4th edn. Saunders Elsevier, Philadelphia p 653–709

    Google Scholar 

  24. Young R (2006) From Krukenberg to today: the ever present problems posed by metastatic tumors in the ovary: part I. Advances in Anatomic Pathology 13:205–227

    Article  PubMed  Google Scholar 

  25. Grabiec J, Owen D (1985) Carcinoma of the stomach in young persons. Cancer 56:388–396

    Article  CAS  PubMed  Google Scholar 

  26. Bhargava R, Dabbs D (2014) Immunohistology of the Breast. In Dabbs DJ (ed) Diagnostic Immunohistochemistry: Theranostic and Genomic Applications. 4th edn. Saunders Elsevier, Philadelphia, p 710–761

    Google Scholar 

  27. Yang C, Sun L, Zhang L et al (2017) Diagnostic utility of SATB2 in metastatic Krukenberg tumors of the ovary: an imunohistochemical study of 70 cases with comparison to CDX2, CK7, chromogranin, and synaptophysin. Am J Surg Pathol 42:160–171

    Article  Google Scholar 

  28. Yu P, Huang L, Cheng G et al (2017) Treatment strategy and prognostic factors for Krukenberg tumors of gastric origin: report of a 10-year single-center experience from China. Oncotarget 8:82558–82570

    PubMed  PubMed Central  Google Scholar 

  29. Rosa F, Marrelli D, Morgagni P et al (2016) Krukenberg tumors of gastric origin: the rationale for surgical resection and perioperative treatments in a multicenter western experience. World J Surg 40:921–8

    Article  Google Scholar 

  30. Lerwill MF, Young RH (2006) Ovarian metastases of intestinal-type gastric carcinoma: a clinicopathologic study of 4 cases with contrasting features to those of the Krukenberg tumor. Am J Surg Pathol 30:1382–8

    Article  PubMed  Google Scholar 

  31. Pilotti S, Rilke F, De Palo G (1982) Krukenberg tumor. Am J Surg Pathol 6(5):486–8

    CAS  PubMed  Google Scholar 

  32. Young RH (2007) From Krukenberg to today: the ever present problems posed by metastatic tumors in the ovary. Part II. Adv Anat Pathol 14(3):149–77

    Article  PubMed  Google Scholar 

  33. Judson K, McCormick C, Vang R, Yemelyanova AV, Wu LS, Bristow RE, Ronnett BM (2008) Women with undiagnosed colorectal adenocarcinomas presenting with ovarian metastases: clinicopathologic features and comparison with women having known colorectal adenocarcinomas and ovarian involvement. Int J Gynecol Pathol 27:182–90

    PubMed  Google Scholar 

  34. Lash RH, Hart WR (1987) Intestinal adenocarcinomas metastatic to the ovaries. A clinicopathologic evaluation of 22 cases. Am J Surg Pathol 11:114–21

    Article  CAS  PubMed  Google Scholar 

  35. Young RH, Hart WR (1998) Metastatic intestinal carcinomas simulating primary ovarian clear cell carcinoma and secretory endometrioid adenocarcinoma. A clinicopathologic and immunohistochemical study of five cases. Am J Surg Pathol 22:805–815.

    Google Scholar 

  36. Pinto C, Pini S, Di Fabio F et al (2014) Treatment strategy for rectal cancer with synchronous metastases: 65 consecutive Italian cases from the Bologna Multidisciplinary rectal cancer group. Oncology 86:135–42

    Article  PubMed  Google Scholar 

  37. Lee SJ, Lee J, Lim HY et al (2010) Survival benefit from ovarian metastatectomy in colorectal cancer patients with ovarian metastasis: a retrospective analysis. Cancer Chemother Pharmacol 66:229–35

    Article  PubMed  Google Scholar 

  38. Aparicio T, Zaanan A, Svrcek M et al (2014) Small bowel adenocarcinoma: epidemiology, risk factors, diagnosis and treatment. Dig Liver Dis 46:97–104

    Article  PubMed  Google Scholar 

  39. Mitsushita J, Netsu S, Suzuki K et al (2017) Metastatic ovarian tumors originating from a small bowel adenocarcinoma—a case report and brief literature review. Int J Gynecol Pathol 36:253–260

    Article  PubMed  Google Scholar 

  40. Kim CJ, Baruch-Oren T, Lin F et al (2016) Value of SATB2 immunostaining in the distinction between small intestinal and colorectal adenocarcinomas. J Clin Pathol 69:1046–1050

    Article  CAS  PubMed  Google Scholar 

  41. Chang HK, Yu E, Kim J et al (2010) Adenocarcinoma of the small intestine: a multi-institutional study of 197 surgically resected cases. Hum Pathol 41:1087–96

    Article  PubMed  Google Scholar 

  42. Hong SH, Koh YH, Rho SY et al (2009) Primary adenocarcinoma of the small intestine: presentation, prognostic factors and clinical outcome. Jpn J Clin Oncol 39:54–61

    Article  PubMed  Google Scholar 

  43. Zaaimi Y, Aparicio T, Laurent-Puig P et al (2016) Advanced small bowel adenocarcinoma: molecular characteristics and therapeutic perspectives. Clin Res Hepatol Gastroenterol 40:154–60

    Article  CAS  PubMed  Google Scholar 

  44. Ronnett BM, Kurman RJ, Shmookler BM et al (1997) The morphologic spectrum of ovarian metastases of appendiceal adenocarcinomas: a clinicopathologic and immunohistochemical analysis of tumors often misinterpreted as primary ovarian tumors or metastatic tumors from other gastrointestinal sites. Am J Surg Pathol 21:1144–55

    Article  CAS  PubMed  Google Scholar 

  45. Merino MJ, Edmonds P, LiVolsi V (1985) Appendiceal carcinoma metastatic to the ovaries and mimicking primary ovarian tumors. Int J Gynecol Pathol 4:110–20

    Article  CAS  PubMed  Google Scholar 

  46. Misdraji J (2015) Mucinous epithelial neoplasms of the appendix and pseudomyxoma peritonei. Mod Pathol 28 Suppl 1:S67–79

    Article  PubMed  Google Scholar 

  47. Young RH, Gilks CB, Scully RE (1991) Mucinous tumors of the appendix associated with mucinous tumors of the ovary and pseudomyxoma peritonei. A clinicopathologic analysis of 22 cases supporting origin in the appendix. Am J Surg Pathol 15:415–429

    Article  CAS  PubMed  Google Scholar 

  48. Dietrich CS 3rd, Desimone CP, Modesitt SC et al (2007) Primary appendiceal cancer: gynecologic manifestations and treatment options. Gynecol Oncol 104:602–6

    Article  PubMed  Google Scholar 

  49. Young RH (2004) Pseudomyxoma peritonei and selected other aspects of the spread of appendiceal neoplasms. Semin Diagn Pathol 21:134–50

    Article  PubMed  Google Scholar 

  50. Ronnett BM, Kurman RJ, Zahn CM et al (1995) Pseudomyxoma peritonei in women: a clinicopathologic analysis of 30 cases with emphasis on site of origin, prognosis, and relationship to ovarian mucinous tumors of low malignant potential. Hum Pathol 26:509–24

    Article  CAS  PubMed  Google Scholar 

  51. Ronnett BM, Seidman JD (2003) Mucinous tumors arising in ovarian mature cystic teratomas: relationship to the clinical syndrome of pseudomyxoma peritonei. Am J Surg Pathol 27:650–7

    Article  PubMed  Google Scholar 

  52. Stewart CJ, Ardakani NM, Doherty DA et al (2014) An evaluation of the morphologic features of low grade mucinous neoplasms of the appendix metastatic in the ovary, and comparison with primary ovarian mucinous tumors. Int J Gynecol Pathol 33:1–10

    Article  PubMed  Google Scholar 

  53. Hristov AC, Young RH, Vang R et al (2007) Ovarian metastases of appendiceal tumors with goblet cell carcinoidlike and signet ring cell patterns: a report of 30 cases. Am J Surg Pathol 31:1502–11

    Article  PubMed  Google Scholar 

  54. Tang LH, Shia J, Soslow RA et al (2008) Pathologic classification and clinical behavior of the spectrum of goblet cell carcinoid tumors of the appendix. Am J Surg Pathol 32:1429–1443

    Article  PubMed  Google Scholar 

  55. Moore L, Gajjar K, Jimenez-Linan M et al (2016) Prevalence of appendiceal lesions in appendectomies performed during surgery for mucinous ovarian tumors: a retrospective study. Int J Gynecol Cancer 26(8):1386–9

    Article  PubMed  Google Scholar 

  56. Ronnett BM, Yan H, Kurman RJ et al (2001) Patients with pseudomyxoma peritonei associated with disseminated peritoneal adenomucinosis have a significantly more favorable prognosis than patients with peritoneal mucinous carcinomatosis. Cancer 92(1):85–91

    Article  CAS  PubMed  Google Scholar 

  57. Young RH, Hart WR (1989) Metastases from carcinomas of the pancreas simulating primary mucinous tumors of the ovary: a report of seven cases. Am J Surg Pathol 13:748–756

    Article  CAS  PubMed  Google Scholar 

  58. Vakiani E, Young RH, Carcangiu ML et al (2008) Acinar cell carcinoma of the pancreas metastatic to the ovary: a report of 4 cases. Am J Surg Pathol 32:1540–1545

    Article  PubMed  Google Scholar 

  59. Basturk O, Farris AB, Adsay V (2014) Immunohistology of the Pancreas and Hepatobiliary Tract. In: Dabbs DJ (ed) Diagnostic Immunohistochemistry: Theranostic and Genomic Applications. 4th edn. Saunders Elsevier, Philadelphia p 540–583

    Google Scholar 

  60. Saung MT, Zheng L (2017) Current standards of chemotherapy for pancreatic cancer. Clin Ther Nov; 39:2125–2134

    Article  CAS  Google Scholar 

  61. Young RH, Scully RE (1990) Ovarian metastasis from carcinoma of the gallbladder and extrahepatic bile ducts simulating primary tumors of the ovary: a report of six cases. Int J Gynecol Pathol 9:60–72

    Article  CAS  PubMed  Google Scholar 

  62. Corr BR, Mantia-Smaldone G, Cantor J et al (2013) Metastatic cholangiocarcinoma to the ovary: a case series. Int J Gynecol Pathol 32:562–5

    Article  PubMed  Google Scholar 

  63. Khunamornpong S, Lerwill MF, Siriaunkgul S et al (2008) Carcinoma of extrahepatic bile ducts and gallbladder metastatic to the ovary: a report of 16 cases. Int J Gynecol Pathol 27:366–379

    Article  PubMed  Google Scholar 

  64. Khunamornpong S, Siriaunkgul S, Suprasert P et al (2007) Intrahepatic cholangiocarcinoma metastatic to the ovary: a report of 16 cases of an underemphasized form of secondary tumor of the ovary that may mimic primary neoplasia. Am J Surg Pathol 31:1788–99

    Article  PubMed  Google Scholar 

  65. Zhuang X, Xiao YP, Tan LH et al (2017) Efficacy and safety of chemotherapy with or without targeted therapy in biliary tract cancer: A meta-analysis of 7 randomized controlled trials. J Huazhong Univ Sci Technolog Med Sci.37:172–178

    Article  Google Scholar 

  66. Rizvi S, Gores GJ (2017) Emerging molecular therapeutic targets for cholangiocarcinoma. J Hepatol Sep;67:632–644

    Article  CAS  Google Scholar 

  67. Khunamornpong S, Siriaunkgul S, Chunduan A (1999) Metastatic hepatocellular carcinoma of the ovary. Int J Gynecol Obstet Feb;64:189–191

    Article  CAS  Google Scholar 

  68. Young RH, Gersell DJ, Clement PB et al (1992) Hepatocellular carcinoma metastatic to the ovary: a report of three cases discovered during life with discussion of the differential diagnosis of hepatoid tumors of the ovary. Hum Pathol 23:574–580

    Article  CAS  PubMed  Google Scholar 

  69. Su J-S, Chen Y-T, Wang R-C et al (2013) Clinicopathological characteristics in the differential diagnosis of hepatoid adenocarcinoma: A literature review. World J Gastroenterol. 19:321–327

    Article  PubMed  PubMed Central  Google Scholar 

  70. Wang EA, Stein JP, Bellavia RJ et al (2017) Treatment options for unresectable HCC with a focus on SIRT with Yttrium-90 resin microspheres. Int J Clin Prac 71(11)

    Article  CAS  Google Scholar 

  71. Robboy SJ, Scully RE, Norris HJ (1974) Carcinoid metastatic to the ovary. A clinicopathologic analysis of 35 cases. Cancer (Phila) 33:798–811

    Article  CAS  PubMed  Google Scholar 

  72. Strosberg J, Nasir A, Cragun J et al (2007) Metastatic carcinoid tumor to the ovary: a clinicopathologic analysis of seventeen cases. Gynecol Oncol 106(1):65–68

    Article  PubMed  Google Scholar 

  73. Mark J, Bush S, Glazer E et al (2015) Metastatic VIPoma presenting as an ovarian mass. Int J Surg Case Rep 17:167–169

    Article  PubMed  PubMed Central  Google Scholar 

  74. Watt DG, Pandanaboyana S, Herrington CS et al (2013) Pancreatic glucagonoma metastasizing to the right ovary five years after initial surgery: a case report. JOP 10;14:510–514

    Google Scholar 

  75. Oberg KC, Wells K, Seraj IM et al (2002) ACTH secreting islet cell tumor of the pancreas presenting as bilateral ovarian tumors and Cushing’s syndrome. Int J Gynecol Pathol 21(3):276–280

    Article  PubMed  Google Scholar 

  76. Brown BL, Scharifker DA, Gordon R et al (1980) Bronchial carcinoid tumor with ovarian metastasis. A light microscopic and ultrasound study. Cancer 46:543–546

    Article  CAS  PubMed  Google Scholar 

  77. Hopping RA, Dockerty MB, Masson JC (1942) Carcinoid tumor of the appendix. Report of a case in which extensive intra-abdominal metastases occurred, including involvement of the right ovary. Arch Surg 45:613–622

    Article  Google Scholar 

  78. Young RH, Scully RE (1985) Ovarian metastasis from cancer of the lung: problems in interpretation—a report of seven cases. Gynecol Oncol 21:337–350

    Article  CAS  PubMed  Google Scholar 

  79. Irving JA, Young RH (2005) Lung carcinoma metastatic to the ovary: a clinicopathologic study of 32 cases emphasizing their morphologic spectrum and problems in differential diagnosis. Am J Surg Pathol 29:997–1006

    PubMed  Google Scholar 

  80. Srivastava A, Hornick JL (2009) Immunohistochemical staining for CDX-2, PDX-1, NESP-55, and TTF-1 can help distinguish gastrointestinal carcinoid tumors from pancreatic endocrine and pulmonary carcinoid tumors. Am J Surg Pathol 33:626–32

    Article  PubMed  Google Scholar 

  81. Rabban JT, Lerwill MF, McCluggage WG et al (2009) Primary ovarian carcinoid tumors may express CDX-2: a potential pitfall in distinction from metastatic intestinal carcinoid tumors involving the ovary. Int J Gynecol Pathol 28:41–48

    Article  PubMed  Google Scholar 

  82. Pasricha G, Padhi P, Daboul N et al (2017) Management of well-differentiated gastroenteropancreatic neuroendocrine tumors (GEPNETs): a review. Clin Ther 39:2146–2157

    Article  CAS  PubMed  Google Scholar 

  83. Young RH, Gersell DJ, Roth LM et al (1993) Ovarian metastasis from cervical carcinomas other than pure adenocarcinomas: a report of 12 cases. Cancer (phila) 15;71:407–418

    Article  CAS  PubMed  Google Scholar 

  84. Ramalingam P, Malpica A, Deavers MT (2012) Mixed endocervical adenocarcinoma and high-grade neuroendocrine carcinoma of the cervix with ovarian metastasis of the former component: a report of 12 cases. Int J Gynecol Pathol 31:490–496

    Article  PubMed  Google Scholar 

  85. Shimada M, Kigawa J, Nishimura R et al (2006) Ovarian metastasis in carcinoma of the uterine cervix. Gynecol Oncol 101:234–237

    Article  PubMed  Google Scholar 

  86. Reyes C, Murali R, Park KJ (2015) Secondary involvement of the adnexa and uterine corpus by carcinomas of the uterine cervix: a detailed morphologic description. Int J Gynecol Pathol 34:551–63

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  87. Nguyen L, Brewer CA, DiSaia PJ (1998) Ovarian metastasis of stage IB1 squamous cell cancer of the cervix after radical parametrectomy and oophoropexy. Gynecol Oncol 68:198–200

    Article  CAS  PubMed  Google Scholar 

  88. Karamurzin YS, Kiyokawa T, Parkash V et al (2015) Gastric type endocervical adenocarcinoma: an aggressive tumor with unusual metastatic patterns and poor prognosis. Am J Surg Pathol 39:1449–57

    Article  PubMed  PubMed Central  Google Scholar 

  89. Zaino R, Whitney C, Brady MF et al (2001) Simultaneously detected endometrial and ovarian carcinomas—a prospective clinicopathologic study of 74 cases. Gynecol Oncol 83:355–362

    Article  CAS  PubMed  Google Scholar 

  90. Kline RC, Wharton JT, Atkinson EN et al (1990) Endometrioid carcinoma of the ovary: retrospective review of 145 cases. Gynecol Oncol 39:337–46

    Article  CAS  PubMed  Google Scholar 

  91. Soliman PT, Slomovitz BM, Broaddus RR et al (2004) Synchronous primary cancers of the endometrium and ovary: a single institution review of 84 cases Gynecol Oncol 94:456–462

    Google Scholar 

  92. Ramus SJ, Elmasry K, Luo Z et al (2008) Predicting clinical outcome in patients diagnosed with synchronous ovarian and endometrial cancer. Clin Cancer Res 14:5840–5848

    Article  PubMed  Google Scholar 

  93. Jain V, Sekhon R, Pasricha S et al (2017) Clinicopathological characteristics and prognostic factors of synchronous endometrial and ovarian cancers- a single-institute review of 43 cases. Int J Gynecol Cancer 27:938–946

    Article  PubMed  Google Scholar 

  94. Lim YK, Padma R, Foo L et al (2011) Survival outcome of women with synchronous cancers of endometrium and ovary: a 10 year retrospective cohort study. J Gynecol Oncol 22:239–243

    Article  PubMed  PubMed Central  Google Scholar 

  95. Bese T, Sal V, Kahramanoglu I, Tokgozoglu N et al (2016) Synchronous primary cancers of the endometrium and ovary with the same histopathologic type versus endometrial cancer with ovarian metastasis: a single institutional review of 72 cases. Int J Gynecol Cancer 26:394–406

    Article  PubMed  Google Scholar 

  96. Kim KR, Scully RE (1990) Peritoneal keratin granulomas with carcinomas of endometrium and ovary and atypical polypoid adenomyoma of endometrium. A clinicopathologic analysis of 22 cases. Am J Surg Pathol 14:925–932

    Article  CAS  PubMed  Google Scholar 

  97. Scully RE, Young RH, Clement PB (1998) Tumors of the ovary, maldeveloped gonads, fallopian tube, and broad ligament. Armed Forces Institute of Pathology, Washington, D.C.

    Google Scholar 

  98. Chao A, Wu RC, Jung SM et al (2016) Implication of genomic characterization in synchronous endometrial and ovarian cancers of endometrioid histology. Gynecol Oncol 143:60–67

    Article  CAS  PubMed  Google Scholar 

  99. Anglesio MS, Wang YK, Maassen M et al (2016) Synchronous Endometrial and Ovarian Carcinomas: Evidence of Clonality. J Natl Cancer Inst 108(6):djv428

    Google Scholar 

  100. Schultheis AM, Ng CK, De Filippo MR et al (2016) Massively Parallel Sequencing-Based Clonality Analysis of Synchronous Endometrioid Endometrial and Ovarian Carcinomas. J Natl Cancer Inst 108(6):djv427

    Article  Google Scholar 

  101. Fadare O, Parkash V, Gwin K et al (2013) Utility of α-methylacyl-coenzyme-A racemase (p504s) immunohistochemistry in distinguishing endometrial clear cell carcinomas from serous and endometrioid carcinomas. Hum Pathol 44:2814–21

    Google Scholar 

  102. Al-Maghrabi JA, Butt NS, Anfinan N et al (2017) Infrequent Immunohistochemical Expression of Napsin A in Endometrial Carcinomas. Appl Immunohistochem Mol Morphol 25:632–638

    Article  CAS  PubMed  Google Scholar 

  103. Koyuncuoğlu M, Saatli B, Yıldırım N (2017) Ovarian metastasis of Müllerian adenosarcoma of the cervix with sarcomatous overgrowth. Turk J Obstet Gynecol 14:195–198

    Article  PubMed  PubMed Central  Google Scholar 

  104. Acosta-Sison H (1958) The relative frequency of various anatomic sites as the point of first metastasis in 32 cases of chorioepithelioma. Am J Obstet Gynecol 75:1149–1152

    Article  CAS  PubMed  Google Scholar 

  105. Milingos D, Doumplis D, Savage P, Seckl M, Lindsay I, Smith JR (2007) Placental site trophoblastic tumor with an ovarian metastasis. Int J Gynecol Cancer 17:925–927

    Article  CAS  PubMed  Google Scholar 

  106. Young RH, Scully RE (1990) Sarcomas metastatic to the ovary. A report of 21 cases. Int J Gynecol Pathol 9:231–252

    Article  CAS  PubMed  Google Scholar 

  107. Young RH, Prat J, Scully RE (1984) Endometrial stromal sarcomas of the ovary. A clinicopathologic analysis of 23 cases. Cancer 53:1143–1155

    Article  CAS  PubMed  Google Scholar 

  108. Khalifa MA, Hansen CH, Moore JL Jr et al (1996) Endometrial stromal sarcoma with focal smooth muscle differentiation: recurrence after 17 years: a follow-up report with discussion of the nomenclature. Int J Gynecol Pathol 15:171–176

    Article  CAS  PubMed  Google Scholar 

  109. Leitao MM, Sonoda Y, Brennan MF et al (2003) Incidence of lymph node and ovarian metastasis in leiomyosarcoma of the uterus. Gynecol Oncol 91:209–212

    Article  PubMed  Google Scholar 

  110. Oliva E, Egger JF, Young RH (2014) Primary endometrioid stromal sarcoma of the ovary: a clinicopathologic study of 27 cases with morphologic and behavioral features similar to those of uterine low-grade endometrial stromal sarcoma. Am J Surg Pathol 38:305–315

    Article  PubMed  Google Scholar 

  111. Savage J, Adams E, Veras E et al (2017) Choriocarcinoma in Women: Analysis of a Case Series With Genotyping. Am J Surg Pathol 41:1593–1606

    Article  PubMed  Google Scholar 

  112. Garavaglia E, Pella F, Montoli S et al (2010) Treatment of recurrent or metastatic low-grade endometrial stromal sarcoma: three case reports. Int J Gynecol Cancer 20:1197–1200

    Article  PubMed  Google Scholar 

  113. Nakamura K, Nakayama K, Ishikawa M et al (2016) Letrozole as second-line hormonal treatment for recurrent low-grade endometrial stromal sarcoma: A case report and review of the literature. Oncol Lett 12:3856–3860

    Article  PubMed  PubMed Central  Google Scholar 

  114. Baek MH, Park JY, Rhim CC et al (2016) Immunohistochemical Characterization of Histone Deacetylase as a Potential Prognostic Marker and Therapeutic Target in Endometrial Stromal Sarcoma. Anticancer Res 36:2527–34

    CAS  PubMed  Google Scholar 

  115. Ricci S, Stone RL, Fader AN (2017) Uterine leiomyosarcoma: Epidemiology, contemporary treatment strategies and the impact of uterine morcellation. Gynecol Oncol. Apr;145:208–216

    Article  PubMed  Google Scholar 

  116. Piek JM, Kenemans P, Verheijen RH (2004) Intraperitoneal serous adenocarcinoma: a critical appraisal of three hypotheses on its cause. Am J Obstet Gynecol 191:718–732

    Article  PubMed  Google Scholar 

  117. Kindelberger DW, Lee Y, Miron A et al (2007) Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma: Evidence for a causal relationship. Am J Surg Pathol 31:161–169

    Article  PubMed  Google Scholar 

  118. Crum CP (2009) Intercepting pelvic cancer in the distal fallopian tube: theories and realities. Mol Oncol 3:165–170

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  119. Kurman RJ, Shih IeM (2010) The origin and pathogenesis of epithelial ovarian cancer: a proposed unifying theory. Am J Surg Pathol 34:433–43

    Article  PubMed  PubMed Central  Google Scholar 

  120. Nik NN, Vang R, Shih IeM et al (2014) Origin and pathogenesis of pelvic (ovarian, tubal, and primary peritoneal) serous carcinoma. Annu Rev Pathol 9:27–45

    Article  CAS  PubMed  Google Scholar 

  121. Vang R, Wheeler JE (2011) Diseases of the fallopian tube and paratubal region. In: Kurman R, Hedrick Ellenson L, Ronnet B (eds) Blaustein’s Pathology of the Female Genital Tract, 6th ed. Springer Science+Business Media LLC, Boston, MA, p 529–578

    Google Scholar 

  122. Alvarado-Cabrero I, Young RH, Vamvakas EC et al (1999) Carcinoma of the fallopian tube: a clinicopathologic study of 105 cases with observations on staging and prognostic factors. Gynecol Oncol 72:367–379

    Article  CAS  PubMed  Google Scholar 

  123. Stewart SL, Wike JM, Foster SL et al (2007) The incidence of primary fallopian tube cancer in the United States. Gynecol Oncol 107:392–397

    Article  PubMed  Google Scholar 

  124. Obermair A, Taylor KH, Janda M et al (2001) Primary fallopian tube carcinoma: the Queensland experience. Int J Gynecol Cancer 11:69–72

    Article  CAS  PubMed  Google Scholar 

  125. Cass I, Holschneider C, Datta N et al (2005) BRCA-mutation-associated fallopian tube carcinoma: a distinct clinical phenotype? Obstet Gynecol 106:1327–1334

    Article  CAS  PubMed  Google Scholar 

  126. Levine DA, Argenta PA, Yee CJ et al (2003) Fallopian tube and primary peritoneal carcinomas associated with BRCA mutations. J Clin Oncol 21:4222–4227

    Article  CAS  PubMed  Google Scholar 

  127. Wheal A, Jenkins R, Mikami Y et al (2017) Primary Mucinous Carcinoma of the Fallopian Tube: Case Report and Review of Literature. Int J Gynecol Pathol 36:393–399

    Article  PubMed  Google Scholar 

  128. Movahedi-Lankarani S, Krishnamurti U, Bell DA et al (2017) Protocol for the examination of specimens from patients with primary tumors of the ovary, fallopian tube, or peritoneum. Version: OvaryFallopian 1.0.0.1. College of American Pathologists (CAP)

    Google Scholar 

  129. McCluggage WG, Hirschowitz L, Gilks CB et al (2017) The Fallopian Tube Origin and Primary Site Assignment in Extrauterine High-grade Serous Carcinoma: Findings of a Survey of Pathologists and Clinicians. Int J Gynecol Pathol 36:230–239

    Article  PubMed  Google Scholar 

  130. Bolton KL, Chenevix-Trench G, Goh C et al (2012) Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer. JAMA 307:382–390

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  131. De Jaeghere E, Vandecasteele K, Claes K et al (2017) Incorporating PARP-inhibitors into clinical routine: A tailored treatment strategy to tackle ovarian cancer. Acta Clin Belg 72:6–11

    Article  PubMed  Google Scholar 

  132. Pimentel C, Becquet M, Lavoue V et al (2016) Ovarian metastasis from breast cancer: a series of 28 cases. Anticancer Res 36:4195–4200

    CAS  PubMed  Google Scholar 

  133. Bigorie V, Morice P, Duvillard P et al (2010) Ovarian metastases from breast cancer: a report of 29 cases. Cancer 116:799–804

    Article  PubMed  Google Scholar 

  134. Gagnon Y, Tetu B (1989) Ovarian metastases of breast carcinoma. A clinicopathologic study of 59 cases. Cancer 64(4):892–898

    Article  CAS  PubMed  Google Scholar 

  135. Struewing JP, Hartge P, Wacholder S et al (1997) The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews. N Eng J Med 336:1401–1408

    Article  CAS  Google Scholar 

  136. Curtin JP, Barakat RR, Hoskins WJ (1994) Ovarian disease in women with breast cancer. Obstet Gynecol 84:449–452

    CAS  PubMed  Google Scholar 

  137. Yagi Y, Maeda T, Yoshimitsu Y et al (2014) A case of breast cancer treated with chemotherapy after resection of giant ovarian metastasis. Gan To Kagaku Ryoho 41:633–635

    PubMed  Google Scholar 

  138. Harris M, Howell A, Chrissohou M et al (1984) A comparison of the metastatic pattern of infiltrating lobular carcinoma and infiltrating ductal carcinoma of the breast. Br J Cancer 50:23–30

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  139. Bennett JA, Young RH, Chuang AY et al (2018) Ovarian metastasis of breast cancers with signet ring cells: a report of 17 cases including 14 Krukenberg tumors. Int J Gynecol Pathol 37:507–515

    CAS  PubMed  Google Scholar 

  140. Hagemann IS, Pfeifer JD, Cao D (2013) Mammaglobin expression in gynecologic adenocarcinomas. Hum Pathol 44:628–635

    Article  CAS  PubMed  Google Scholar 

  141. Miettinen M, McCue PA, Sarlomo-Rikala M et al (2014) GATA3: a multispecific but potentially useful marker in surgical pathology: a systematic analysis of 2500 epithelial and nonepithelial tumors. Am J Surg Pathol 38:13–22

    Article  PubMed  PubMed Central  Google Scholar 

  142. Thway K, Noujaim J, Zaidi S et al (2016) Desmoplastic Small Round Cell Tumor: Pathology, Genetics, and Potential Therapeutic Strategies. Int J Surg Pathol 24:672–684

    Article  CAS  PubMed  Google Scholar 

  143. Fenzl V, Prkacin I, Skrtic A (2011) Malignant melanoma ovarian metastasis mimicking acute tuboovarian abscess. Eur J Gynaecol Oncol 32:582–584

    CAS  PubMed  Google Scholar 

  144. Mandato VD, Kobal B, Di Stefano A et al (2010) Choroidal melanoma metastasized to the ovary: case report and review of the literature. Eur J Gynaecol Oncol. 31:109–113

    CAS  PubMed  Google Scholar 

  145. Fitzgibbons PL, Martin SE, Simmons TJ (1987) Malignant melanoma metastatic to the ovary. Am J Surg Pathol 11:959–964

    Article  CAS  PubMed  Google Scholar 

  146. Gupta D, Deavers MT, Silva EG et al (2004) Malignant melanoma involving the ovary: a clinicopathologic and immunohistochemical study of 23 cases. Am J Surg Pathol 28:771–80

    Article  PubMed  Google Scholar 

  147. Young RH, Scully RE (1991) Malignant melanoma metastatic to the ovary: a clinicopathologic analysis of 20 cases. Am J Surg Pathol 15:849–860

    Article  CAS  PubMed  Google Scholar 

  148. Lobo J, Pinto C, Freitas M et al (2017) Ovarian metastasis from uveal melanoma with MLH1/PMS2 protein loss in a patient with germline MLH1 mutated lynch syndrome: consequence or coincidence? Virchows Arch 470:347–352

    Article  CAS  PubMed  Google Scholar 

  149. Karateke A, Tuğ N, Sahin D (2011) Metastatic ovarian malignant melanoma with no obvious primary. J Turk Ger Gynecol Assoc 12:181–182

    Article  PubMed  PubMed Central  Google Scholar 

  150. Prieto VG. Immunohistology of melanocytic neoplasms (2014) In Dabbs DJ (ed) Diagnostic Immunohistochemistry:Theranostic and Genomic Applications. 4th edn. Saunders Elsevier, Philadelphia

    Google Scholar 

  151. McCluggage WG, Bissonnette JP, Young RH et al (2006) Primary malignant melanoma of the ovary: a report of 9 definite or probable cases with emphasis on their morphologic diversity and mimicry of other primary and secondary ovarian neoplasms. Int J Gynecol Pathol 25:321–329

    Article  PubMed  Google Scholar 

  152. Zikry J, Korta DZ, Chapman LW et al (2017) Melanoma arising in an ovarian cystic teratoma: a systematic review of presentation, treatment, and outcomes. Arch Gynecol Obstet 296:397–404

    Article  PubMed  Google Scholar 

  153. Liang L, Huang H, Dadhania V et al (2016) Renal cell carcinoma metastatic to the ovary or fallopian tube: a clinicopathological study of 9 cases. Hum Pathol 51:96–102

    Article  PubMed  PubMed Central  Google Scholar 

  154. Young RH, Hart WR (1992) Renal cell carcinoma metastatic to the ovary: a report of three cases emphasizing possible confusion with ovarian clear cell carcinoma. Int J Gynecol Pathol 11:96–104

    Article  CAS  PubMed  Google Scholar 

  155. Fadare O, Desouki MM, Gwin K et al (2017) Clear Cell Renal Cell Carcinoma Metastatic to the Gynecologic Tract: A Clinicopathologic Analysis of 17 Cases. Int J Gynecol Pathol 37:525–535

    Google Scholar 

  156. Kassouf W, Binsaleh S, Cohen DD et al (2004) Bellini duct carcinoma with ovarian metastasis. Can J Urol. 11:2461–2462

    CAS  PubMed  Google Scholar 

  157. Netto GJ, Epstein JI (2014) Immunohistology of the bladder, kidney and testis. In: Dabbs DJ (ed) Diagnostic Immunohistochemistry:Theranostic and Genomic Applications. 4th edn. Saunders Elsevier, Philadelphia

    Google Scholar 

  158. Irving JA, Vasques DR, McGuinness TB et al (2006) Krukenberg tumor of renal pelvic origin: report of a case with selected comments on ovarian tumors metastatic from the urinary tract. Int J Gynecol Pathol 25:147–150

    Article  PubMed  Google Scholar 

  159. Young RH, Scully RE (1998) Urothelial and ovarian carcinomas of identical cell types: problems in interpretation. A report of three cases and review of the literature. Int J Gynecol Pathol 7:197–211

    Article  CAS  PubMed  Google Scholar 

  160. Min KW, Paik SS, Han H et al (2014) Tumour-to-tumour metastasis of lung adenocarcinoma to ovarian serous cystadenoma. J Obstet Gynaecol 34:650–651 

    Article  PubMed  Google Scholar 

  161. Huysentruyt CJ, Vandevijver NM, Jan van Suylen R et al (2010) Adenocarcinoma of the fetal lung-type metastatic to the ovary. Int J Gynecol Pathol 29:339–40

    Article  PubMed  Google Scholar 

  162. Yu L, Li X, Yang W (2009) Pulmonary blastoma metastatic to the ovary. Int J Gynecol Pathol 28:59–62

    Article  PubMed  Google Scholar 

  163. Martín-Hernández R, Villanueva MM, Sánchez MN et al (2015) Ovarian Metastasis of a Thymoma: Report of a Case and Literature Review. Int J Gynecol Pathol 34:374–8

    PubMed  Google Scholar 

  164. Young RH, Kozakewich HP, Scully RE (1993) Metastatic ovarian tumors in children: a report of 14 cases and review of the literature. Int J Gynecol Pathol 12:8–19

    Article  CAS  PubMed  Google Scholar 

  165. Freeman C, Berg JW, Cutler SJ (1972) Occurrence and prognosis of extranodal lymphomas. Cancer 29:252–60

    Article  CAS  PubMed  Google Scholar 

  166. Halpin TF (1975) Gynecologic implications of Burkitt's tumor. Obstet Gynecol Surv 30:351–358

    Article  CAS  PubMed  Google Scholar 

  167. Vang R, Medeiros LJ, Warnke RA et al (2001) Ovarian non-Hodgkin's lymphoma: a clinicopathologic study of eight primary cases. Mod Pathol 14:1093–1099

    Article  CAS  PubMed  Google Scholar 

  168. Osborne BM, Robboy SJ (1983) Lymphomas or leukemia presenting as ovarian tumors. An analysis of 42 cases. Cancer 52:1933–1943

    Article  CAS  PubMed  Google Scholar 

  169. Monterroso V, Jaffe ES, Merino MJ et al (1993) Malignant lymphomas involving the ovary. A clinicopathologic analysis of 39 cases. Am J Surg Pathol 17:154–170

    Article  CAS  PubMed  Google Scholar 

  170. Chorlton I, Norris HJ, King FM (1974) Malignant reticuloendothelial disease involving the ovary as a primary manifestation: a series of 19 lymphomas and 1 granulocytic sarcoma. Cancer 34:397–407

    Article  CAS  PubMed  Google Scholar 

  171. Fox H, Langley FA, Govan AD et al (1988) Malignant lymphoma presenting as an ovarian tumour: a clinicopathological analysis of 34 cases. Br J Obstet Gynaecol. 5:386–390

    Article  Google Scholar 

  172. Emery JD, Kennedy AW, Tubbs RR et al (1999) Plasmacytoma of the ovary: a case report and literature review. Gynecol Oncol 73:151–154

    Article  CAS  PubMed  Google Scholar 

  173. Mondal SK, Chatterjee S, Mandal S et al (2015) Primary extramedullary plasmacytoma of ovary: Report of a rare neoplasm. J Cancer Res Ther 11:923–4

    Article  CAS  PubMed  Google Scholar 

  174. Zhong YP, Zhang JJ, Huang XN (2012) Multiple myeloma with rupture of ovarian plasmacytoma. Chin Med J (Engl) 125:2948–2950

    Google Scholar 

  175. Hirsch MS (2011) Metastatic Tumors of the Ovary. In: Crum CP, Nucci MR, Lee KR (eds) Diagnostic Gynecologic and Obstetric Pathology, 2nd edn. Elsevier Saunders, Philadelphia, p 972–988

    Chapter  Google Scholar 

  176. Oliva E, Ferry JA, Young RH et al (1997) Granulocytic sarcoma of the female genital tract: a clinicopathologic study of 11 cases. Am J Surg Pathol 21:1156–1165

    Article  CAS  PubMed  Google Scholar 

  177. Barcos M, Lane W, Gomez GA et al (1987) An autopsy study of 1206 acute and chronic leukemias (1958 to 1982). Cancer 60:827–837

    Article  CAS  PubMed  Google Scholar 

  178. Pais RC, Kim TH, Zwiren GT et al (1991) Ovarian tumors in relapsing acute lymphoblastic leukemia: a review of 23 cases. J Pediatr Surg 26:70–74

    Article  CAS  PubMed  Google Scholar 

  179. Cunningham I (2013) The clinical behavior of 124 leukemic ovarian tumors: clues for improving the poor prognosis. Leuk Lymphoma 54:1430–6

    Article  PubMed  Google Scholar 

  180. Terek MC, Ozkinay E, Zekioglu O et al (2003) Acute leukemia in pregnancy with ovarian metastasis: a case report and review of the literature. Int J Gynecol Cancer 13:904–8

    Article  CAS  PubMed  Google Scholar 

  181. Terek MC, Ozkinay E, Zekioglu O et al (2003) Acute leukemia in pregnancy with ovarian metastasis: a case report and review of the literature. Int J Gynecol Cancer 13:904–8

    Article  CAS  PubMed  Google Scholar 

  182. Young RH, Jackson A, Wells M (1994) Ovarian metastasis from thyroid carcinoma 12 years after partial thyroidectomy mimicking struma ovarii: report of a case. Int J Gynecol Pathol 13:181–185

    Article  CAS  PubMed  Google Scholar 

  183. Logani S, Baloch ZW, Snyder PJ et al (2001) Cystic ovarian metastasis from papillary thyroid carcinoma: a case report. Thyroid 11:1073–1075

    Article  CAS  PubMed  Google Scholar 

  184. Brogioni S, Viacava P, Tomisti L et al (2007) A special case of bilateral ovarian metastases in a woman with papillary carcinoma of the thyroid. Exp Clin Endocrinol Diabetes 115:397–400

    Article  CAS  PubMed  Google Scholar 

  185. Besic N, Gazic B (2013) Sites of metastases of anaplastic thyroid carcinoma: autopsy findings in 45 cases from a single institution. Thyroid 23:709–713

    Article  PubMed  Google Scholar 

  186. Longacre TA, O'Hanlan K, Hendrickson MR (1996) Adenoid cystic carcinoma of the submandibular gland with symptomatic ovarian metastases. Int J Gynecol Pathol 15:349–55

    Article  CAS  PubMed  Google Scholar 

  187. Riopel MA, Ronnett BM, Kurman RJ (1999) Evaluation of diagnostic criteria and behavior of ovarian intestinal-type mucinous tumors: atypical proliferative (borderline) tumors and intraepithelial, microinvasive, invasive, and metastatic carcinomas. Am J Surg Pathol 23:617–35

    Article  CAS  PubMed  Google Scholar 

  188. Eichhorn JH, Young RH, Scully RE (1993) Nonpulmonary small cell carcinomas of extragenital origin metastatic to the ovary. Cancer 71:177–186

    Article  CAS  PubMed  Google Scholar 

  189. Açıkalın A, Paydaş S, Güleç ÜK et al (2014) A unique case of merkel cell carcinoma with ovarian metastasis. Balkan Med J 31:356–359

    Article  PubMed  PubMed Central  Google Scholar 

  190. Zukerberg LR, Young RH (1990) Chordoma metastatic to the ovary. Arch Pathol Lab Med 114:208–210

    CAS  PubMed  Google Scholar 

  191. Rubio A, Schuldt M, Chamorro C et al (2015) Ovarian Small Cell Carcinoma of Pulmonary Type Arising in Mature Cystic Teratomas With Metastases to the Contralateral Ovary. Int J Surg Pathol 23:388–92

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Departments of Pathology, Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX, USA

    Kelley Carrick & Wenxin Zheng

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  1. Kelley Carrick
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  2. Wenxin Zheng
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Correspondence to Kelley Carrick .

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Editors and Affiliations

  1. Department of Pathology, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX, USA

    Wenxin Zheng

  2. Department of Pathology, University of California San Diego, San Diego, CA, USA

    Oluwole Fadare

  3. Department of Pathology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA

    Charles Matthew Quick

  4. Department of Pathology, Peking University People’s Hospital, Beijing, China

    Danhua Shen

  5. Department of Obstetrics and Gynecology, Tianjin Gynecologic and Obstetrics Central Hospital, Tianjin, China

    Donghui Guo

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Carrick, K., Zheng, W. (2019). Secondary Tumors of the Ovary. In: Zheng, W., Fadare, O., Quick, C., Shen, D., Guo, D. (eds) Gynecologic and Obstetric Pathology, Volume 2. Springer, Singapore. https://doi.org/10.1007/978-981-13-3019-3_10

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