Abstract
The role of the esophagus is to transport food to the stomach rapidly and safely. The transportation of food is controlled by the complex esophageal motility of the upper and lower esophageal sphincters which operate in a precise manner to produce peristaltic contraction. Patients with functional esophageal diseases such as gastroesophageal reflux disease (GERD), esophageal achalasia, and ineffective esophageal motility (IEM) often suffer from various symptoms of dyspepsia, including dysphagia, chest pain, heartburn, epigastralgia, bloating, nausea, foreign-body sensation, and discomfort.
On the other hand, functional dyspepsia (FD) is mainly caused by gastric functional disorder, but its symptoms often coincide with GERD. Therefore, distinguishing the two diseases may be difficult as there are common pathological conditions. Motility function disorders such as impaired gastric accommodation and delayed gastric emptying reduce clearance in the upper gastrointestinal tract and become the cause of both diseases and an exacerbating factor. Although the stomach and esophagus are anatomically different organs, they are considered to form one unit of the upper gastrointestinal tract that serves the same purpose of achieving digestion.
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Odaka, T. (2018). Neuro-gastroenterology: Esophagogastric Function (Motility). In: Tominaga, K., Kusunoki, H. (eds) Functional Dyspepsia. Springer, Singapore. https://doi.org/10.1007/978-981-13-1074-4_6
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DOI: https://doi.org/10.1007/978-981-13-1074-4_6
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