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Clinical Applications of Injectable Biomaterials

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Novel Biomaterials for Regenerative Medicine

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1077))

Abstract

Regenerative medicine is an interdisciplinary field that aims to regenerate the lost or diseased tissues through the combinational use of cells, biomolecules and/or biomaterials. Injectable biomaterials have been comprehensively evaluated for use in this field for their prominent properties, such as ease of handling, providing a better integration of the native tissue by filling irregular defects and having controllable chemical and physical properties. This class of biomaterials can be developed from natural or synthetic origin materials, decellularized matrices or from combinations of materials to form composites. Injectable biomaterials enable minimally invasive approach when compared with traditional open surgeries, which can reduce the cost, and speed up the recovery time for the patients. Cells, growth factors and/or bioactive molecules can be effectively delivered to the target tissue using injectable biomaterials, making them desirable for a number of clinical applications. This chapter gives an overview on injectable biomaterials and their clinical applications in soft, hard, and cardiovascular tissue regeneration.

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Competing Interests

Y.M.E. is the founder and director of Biovalda, Inc. (Ankara, Turkey). The authors declare no competing interests in relation to this article.

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Authors and Affiliations

  1. Tissue Engineering, Biomaterials and Nanobiotechnology Laboratory, Faculty of Science, Stem Cell Institute, Ankara University, Ankara, Turkey

    Hatice Ercan, Serap Durkut, Aysel Koc-Demir, Ayşe Eser Elçin & Yaşar Murat Elçin

  2. Biovalda Health Technologies, Inc., Ankara, Turkey

    Yaşar Murat Elçin

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  1. Hatice Ercan
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  1. The Catholic University of Korea, Seoul, Korea (Republic of)

    Heung Jae Chun

  2. Korea Institute of Science and Technology, Seoul, Korea (Republic of)

    Kwideok Park

  3. Korea Institute of Radiological and Medical Sciences, Seoul, Korea (Republic of)

    Chun-Ho Kim

  4. Chonbuk National University, Jeonju, Korea (Republic of)

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Ercan, H., Durkut, S., Koc-Demir, A., Elçin, A.E., Elçin, Y.M. (2018). Clinical Applications of Injectable Biomaterials. In: Chun, H., Park, K., Kim, CH., Khang, G. (eds) Novel Biomaterials for Regenerative Medicine. Advances in Experimental Medicine and Biology, vol 1077. Springer, Singapore. https://doi.org/10.1007/978-981-13-0947-2_10

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