Abstract
Laser beam micro-channeling process has an immense potential for the fabrication of microfluidic devices which are instrumental for various biomedical applications such as electrophoresis, chromatography, blood protein analysis, DNA studies, micro-total analysis systems, etc. In the current study, an attempt has been made to fabricate micro-channels in a thick polymethyl methacrylate (PMMA) plate having 11.328 mm thickness at partially submerged condition by utilizing laser transmission micro-machining technology. An Nd:YAG laser source has been employed with a wavelength of 1064 nm. The working power is used for which the micro-channel fabrication varies between 9 and 11 W, pulse frequency varies between 25 and 45 kHz, pulse width varies between 90 and 98% of the duty cycle, and cutting speed ranges from 1.00 to 2.00 mm/sec. The effects of parameters on heat-affected zone (HAZ) width during laser transmission micro-channeling have been investigated. Totally, 31 experiments have been designed and performed with the aid of central composite design technique based on response surface methodology (RSM). Finally, optimization of the aforesaid process parameters has been performed in order to achieve minimum dimension of HAZ width within the predefined design space, for utilizing in various microfluidic applications.
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Biswas, S., Roy, N., Biswas, R., Kuar, A.S. (2019). Experimental Investigations into Underwater Laser Transmission Micro-channeling on PMMA. In: Dixit, U., Joshi, S., Davim, J. (eds) Application of Lasers in Manufacturing. Lecture Notes on Multidisciplinary Industrial Engineering. Springer, Singapore. https://doi.org/10.1007/978-981-13-0556-6_9
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