Abstract
Medicinal plants are used by 80% of the world population for their primary health care. The medicinal value of plants is primarily attributed to the secondary metabolite content such as terpenoids, alkaloids, and phenolics. These compounds play a crucial role in plant defense, are merchandised valued for their therapeutic applications and ecological role, and are also used as flavoring agents. Arbuscular mycorrhizal fungi (AMF) or Glomeromycota is known to form a symbiotic relationship with many terrestrial plants. AM fungi–plant consortium enhanced the production of plant terpenoids, alkaloids, and phenolics, which are valuable to human health. The potential role of arbuscular mycorrhiza (AM) symbiosis in amplification of the secondary metabolite content has attained enormous recognition for sustainable cultivation of medicinally important crops. AMF–plant symbiosis not only improves the growth and nutrients but also exerts a synergistic effect on accumulation of bioactive compounds with medicinal importance. Current studies have also recognized AM-mediated modulation of morphology, biochemistry, and gene expression in medicinal as well as in the industrial important plants. This chapter provides an appraisal on contemporary finding in the area of AMF investigation with a marked emphasis on the yield of pharmaceutically important plant-derived secondary metabolites.
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References
Abu-Zeyad R, Khan AG, Khoo C (1999) Occurrence of arbuscular mycorrhiza in Castanospermum australe A. Cunn. & C. Fraser and effects on growth and production of castanospermine. Mycorrhiza 9:111–117
Adams RP, Habte M, Park S, Dafforn MR (2004) Preliminary comparison of vetiver root essential oils from cleansed (bacteria-and fungus-free) versus non-cleansed (normal) vetiver plants. Biochem Syst Ecol 32(12):1137–1144
Akiyama K, Hayashi H (2002) Arbuscular mycorrhizal fungus-promoted accumulation of two new triterpenoids in cucumber roots. Biosci Biotechnol Biochem 66(4):762–769
Allen MF, Moore TS, Christensen M (1980) Phytohormone changes in Bouteloua gracilis infected by vesicular-arbuscular mycorrhizae. I. Cytokinin increases in the host plant. Can J Bot 58:371–374
Allen MF, Moore TS, Christensen M (1982) Phytohormone changes in Bouteloua gracilis infected by vesicular-arbuscular mycorrhizae. II. Altered levels of gibberellin-like substances and abscisic acid in the host plant. Can J Bot 60:468–471
Andrade SAL, Malik S, Sawaya ACHF, Bottcher A, Mazzafera P (2013) Association with arbuscular mycorrhizal fungi influences alkaloid synthesis and accumulation in Catharanthus roseus and Nicotiana tabacum plants. Acta Physiol Plant 35(3):867–880
Araim G, Saleem A, Arnason JT, Charest AC (2009) Root colonization by an arbuscular mycorrhizal (AM) fungus increases growth and secondary metabolism of purple coneflower, Echinacea purpurea (L.) Moench. J Agric Food Chem 57:2255–2258
Arpana J, Bagyaraj DJ, Prakasa Rao EVS, Parameswaran TN, Abdul Rahiman BA (2008) Symbiotic response of patchouli [Pogostemon cablin (Blanco) Benth.] to different arbuscular mycorrhizal fungi. Adv Environ Biol 2(1):20–24
Asrar AWA, Elhindi KM (2010) Elhindi. Alleviation of drought stress of marigold (Tagetes erecta) plants by using arbuscular mycorrhizal fungi. Saudi J Biol Sci 18(1):93–98
Augé RM (2001) Water relations, drought and vesicular-arbuscular mycorrhizal symbiosis. Mycorrhiza 11(1):3–42
Awasthi A, Bharti N, Nair N, Singh R, Shukla AK, Gupta MM, Darokar MP, Kalra A (2011) Synergistic effect of Glomus mosseae and nitrogen fixing Bacillus subtilis strain Daz26 on artemisinin content in Artemisia annua L. Appl Soil Ecol 49:125–130
Bagheri S, Ebrahimi MA, Davazdahemami S, Minooyi J (2014) Terpenoids and phenolic compounds production of mint genotypes in response to mycorrhizal bio-elicitors. Tech J Eng Appl Sci 4:339–348
Bagyaraj D J, Varma A (1995) Interaction between arbuscular mycorrhizal fungi and plants. In Advances in Microbial Ecology Springer, Boston pp 119–142
Barrios E (2007) Soil biota, ecosystem services and land productivity. Ecol Econ 64:269–285
Bian XJ, Hu L, Li XL, Zhang FS (2001) Effect of VA mycorrhiza on the turfgrass quality and mineral nutrient uptakes. Acta Pratacul Sin 10(3):42–46
Binet MN, Van Tuinen D, Deprêtre N, Koszela N, Chambon C, Gianinazzi S (2011) Arbuscular mycorrhizal fungi associated with Artemisia umbelliformis Lam, an endangered aromatic species in Southern French Alps, influence plant P and essential oil contents. Mycorrhiza 21:523–535
Boby VU, Bagyaraj DJ (2003) Biological control of root-rot of Coleus forskohlii Briq. using microbial inoculants. World J Microbiol Biotechnol 19(2):175–180
Boller T, Wiemken A (1986) Dynamics of vacuolar compartmentation. Annu Rev Plant Physiol 37(1):137–164
Borde M, Dudhane M, Jite PK (2009) Role bioinoculant (AM fungi) increasing in growth, flavor content and yield in Allium sativum L. under field condition. Not Bot Hortic Agrobot Cluj 37(2):124–128
Cai BY, Jie WG, Ge JP, Yan XF (2008) Molecular detection of the arbuscular mycorrhizal fungi in the rhizosphere of Phellodendron amurense. Mycosystema 27(6):884–893
Cao DX, Zhao JL (2007) The investigation of arbuscular mycorrhizal fungi and soil factors from the rhizospere of medicinal plant Angelica dahurica. Acta Agric Boreali-Sin 22:47–50
Copetta A, Lingua G, Berta G (2006) Effects of three AM fungi on growth, distribution of glandular hairs, and essential oil production in Ocimum basilicum L. var. Genovese. Mycorrhiza 16:485–494
Chaudhary V, Kapoor R, Bhatnagar AK (2008) Effectiveness of two arbuscular mycorrhizal fungi on concentrations of essential oil and artemisinin in three accessions of Artemisia annua L. Appl Soil Ecol 40:174–181
Chen LT, Guo QS, Liu ZY (2009a) Colonization pattern and dynamic change of arbuscular mycorrhizal fungi in Pinellia ternate. Guizhou Agric Sci 37(2):37–39
Chen LT, Liu ZY, Guo QS, Zhu GS (2009b) Advances in studies on arbuscular mycorrhizas in medicinal plants. Chin Tradit Herb Drugs 40(1):156–160
Chen LT, Guo QS, Liu ZY (2010) Arbuscular mycorrhiza of cultivated and wild Pinellia ternate. Chin J Chin Mater Med 35(4):405–410
Cho EJ, Lee DJ, Wee CD, Kim HL, Cheong YH, Cho JS, Sohn BK (2009) Effects of AM FUNGI inoculation on growth of Panax ginseng C.A. Meyer seedlings and on soil structures in mycorrhizosphere. Sci Hortic 122(4):633–637
Clark RB, Zeto SK (2000) Mineral acquisition by arbuscular mycorrhizal plants. J Plant Nutr 23(7):867–902
Cordell GA (1995) Changing strategies in natural products chemistry. Phytochem 40(6):1585–1612
Corizier R (1974) In: Kleinman VS et al. (eds) Medicine in Chinese Culture, Department of Health, Education and Welfare Publications, pp 26
Croteau R, Kutchan TM, Lewis NG (2000) Natural products (secondary metabolites). Biochem Mol Biol 24:1250–1319
David S (2000) The history of WWII medicine. http://home.att.net/~steinert/wwii.htm
De la Rosa-Mera CJ, Ferrera-Cerrato R, Alarcón A, de Jesús Sánchez-Colín M, Muñoz-Muñiz OD (2011) Arbuscular mycorrhizal fungi and potassium bicarbonate enhance the foliar content of the vinblastine alkaloid in Catharanthus roseus. Plant Soil 349(1–2):367–376
El-Sayed M, Verpoorte R (2007) Catharanthus terpenoid indole alkaloids: biosynthesis and regulation. Phytochem Rev 6(2–3):277–305
Fan JH, Yang GT, Mu LQ, Zhou JH (2006) Effect of AM fungi on the content of berberine, jatrorrhizine and palmatine of Phellodendron amurense seedings. Prot For Sci Technol 5:24–26
Farahani HA, Lebaschi MH, Hamidi A (2008) Effects of arbuscular mycorrhizal fungi, phosphorus and water stress on quantity and quality characteristics of coriander. J Adv Nat Appl Sci 2(2):55–59
Feng G, Zhang F, Li X, Tian C, Tang C, Rengel Z (2002) Improved tolerance of maize plants to salt stress by arbuscular mycorrhiza is related to higher accumulation of soluble sugars in roots. Mycorrhiza 12(4):185–190
Floß DS, Hause B, Lange PR, Küster H, Strack D, Walter MH (2008) Knock-down of the MEP pathway isogene 1-deoxy-d-xylulose 5-phosphate synthase 2 inhibits formation of arbuscular mycorrhiza-induced apocarotenoids, and abolishes normal expression of mycorrhiza-specific plant marker genes. Plant J 56(1):86–100
Fransworth NR, Akerele O, Bingel AS, Soejarto DD, Guo Z (1985) Drugs from medicinal plants. Bull WHO 63:965–981
Freitas MSM, Martins MA, Vieira IJC (2004) Yield and quality of essential oils of Mentha arvensis in response to inoculation with arbuscular mycorrhizal fungi. Pesq Agropec Bras 39(9):887–894
Galbley S, Thiericke R (1999) Drug Discovery FROM Nature. Springer, Berlin
Geneva MP, Stancheva IV, Boychinova MM, Mincheva NH, Yonova PA (2010) Effects of foliar fertilization and arbuscular mycorrhizal colonization on Salvia officinalis L. growth, antioxidant capacity, and essential oil composition. J Sci Food Agric 90:696–702
Gershenzon J, Kreis W (1999) Biochemistry of terpenoids: monoterpenes, sesquiterpenes, diterpenes, sterols, cardiac glycosides and steroid saponins. Biochem Plant Sec Met 2:222–299
Ghisalberti EL (1993) Detection and isolation of bioactive natural products. In: Colegate SM, Molyneux RJ (eds) Bioactive natural products: detection, isolation, and structural determination. CRC Press, Boca Raton, pp 9–57
Gianinazzi S, Gollotte A, Binet MN, Tuinen DV, Redecker D, Wipf D (2010) Agroecology: the key role of arbuscular mycorrhizas in ecosystem services. Mycorrhiza 20:519–530
Gong MQ, Wang FZ, Chen Y (2002) Study on application of arbuscular-mycorrhizas in growing seedling of Aloe vera. J Chin Med Mater 25(1):1–3
Gopal RM (2001) J Med Aromat Plant Sci, 22/4A & 23/1A, 572
Guerrieri E, Lingua G, Digilio MC, Massa N, Berta G (2004) Do interactions between plant roots and the rhizosphere affect parasitoid behaviour? Ecol Entomol 29(6):753–756
Guo LP, Wang HG, Hang LQ (2006) Effects of arbuscular mycorrhizae on growth and essential oil of Atractylodes lancea. Chin J Chin Mater Med 31(8):1491–1495
Guo QS, Chen LT, Liu ZY (2010) Study on influence of arbuscular mycorrhizal fungi on Pinellia ternata yield and chemical composition. Chin J Chin Med 35(3):333–338
Gupta ML, Prasad A, Ram M, Kumar S (2002) Effect of the vesicular-arbuscular mycorrhizal (VAM) fungus Glomus fasciculatum on the essential oil yield related characters and nutrient acquisition in the crops of different cultivars of menthol mint (Mentha arvensis) under field conditions. Bioresour Technol 81(1):77–79
Hadwiger A, Neimann H, Kaebisch A, Bauer H, Tamura T (1986) Appropriate glucosylation of the FMS gene product is a prerequisite for its transforming potency. EMBO J 5:689–694
Harris JC, Cottrell S, Plummer S, Lloyd D (2001) Antimicrobial properties of Allium sativum (garlic). Appl Microbiol Biotechnol 57:282–286
Harrison M (1999) Molecular and cellular aspects of the arbuscular mycorrhizal symbiosis. Annu Rev Plant Biol 50:361–389
Hart MM, Trevors JT (2005) Microbe management: application of mycorrhyzal fungi in sustainable agriculture. Front Ecol Environ 310:533–539
Herbert RB (2001) The biosynthesis of plant alkaloids and nitrogenous microbial metabolites. Nat Prod Rep 18(1):50–65
He XL, Li J, Gao AX, Zhao LL, Zao JL (2009a) Effects of different host plants on the development of AM fungi in the rhizospere of Salvia miltiorrhiza. J Hebei Univ 29(5):533–537
He XL, Li J, He C (2009b) Effects of AM fungi on the chemical components of Salvia miltiorrhiza Bge. Chin Agric Sci Bull 25(14):182–185
He XL, Liu T, Zhao LL (2009c) Effects of inoculating AM fungi on physiological characters an nutritional components of Astragalus membranaceus under different N application levels. Chin J Appl Ecol 20(9):2118–2122
He XL, Wang LY, Ma J, Zhao LL (2010) AM fungal diversity in the rhizosphere of Salvia miltiorrhiza in Anguo city of Hebei province. Biodivers Sci 18(2):187–194
Hodge A, Campbell CDFAH (2001) An arbuscular mycorrhizal fungus accelerates decomposition and acquires nitrogen directly from organic material. Nature 413:297–299
Hostettmann K, Marston A, Ndjoko K, Wolfender JL (2000) The potential of African plants as a source of drugs. Curr Org Chem 4(10):973–1010
Huang KC (1999) The pharmacology of Chinese herbs: a brief history of Chinese medicine, 2nd edn. CRC Press, Boca Raton, pp 1–16
Huang YF, Li HH, Chen HY, Li Y (2003) Preliminary study on the mycorrhiza inoculation on the seeding of camptotheca acuminate. Guangdong For Sci Technol 19(1):40–42
Huang LQ, Chen ML, Xiao PG (2004) The modern biological basis and model hypothesis on the research of genuineness of Chinese herbal medicine. Chin J Chin Mater Med 29(6):494–496
Huang JH, Tan JF, Jie HK, Zeng RS (2011) Effects of invoculating arbuscular mycorrhizal fungi on Artemisia annua growth and its officinal components. Chin J Appl Ecol 22(6):1443–1449
Ishibashi A (2002) In: Complementary and alternative medicine in Japan, SY19-4
Janardhanan KK, Abdul-Khaliq K (1995) Influence of vesicular arbuscular mycorrhizal fungi on growth and productivity of German chamomile in alkaline usar soil. In: Adholeya A, Singh S (eds) Mycorrhizae: biofertilizers for the future. Tata Energy Research Institute, New Delhi, pp 410–412
Jeffries P, Gianinazzi S, Peretto S, Turnau K, Barea JM (2003) The contribution of arbuscular mycorrhizal fungi in sustainable maintenance of plant health and soil fertility. Biol Fertil Soils 37:1–16
Jie WG, Cai BY, Ge JP, Yan XF (2007) Identification of arbuscular mycorrhizal fungi of Phellodendren amurense Rupr. Biotechnology 17(6):32–35
Jugran AK, Bahukhandi A, Dhyani P, Bhatt ID, Rawal RS, Nandi SK, Palni LMS (2015) The effect of inoculation with mycorrhiza: AM on growth, phenolics, tannins, phenolic composition and antioxidant activity in Valeriana jatamansi Jones. J Soil Sci Plant Nutr 15(4):1036–1049
Jurkiewicz A, Ryszka P, Anielska T, Waligórski P, Białońska D, Góralska K, Michael MT, Turnau K (2010) Optimization of culture conditions of Arnica montana L.: effects of mycorrhizal fungi and competing plants. Mycorrhiza 20:293–306
Kapoor R, Giri B, Mukerji KG (2002a) Glomus macrocarpum: a potential bioinoculant to improve essential oil quality and concentration in Dill (Anethum graveolens L.) and Carum (Trachyspermum ammi (Linn.) Sprague). World J Microbiol Biotechnol 18(5):459–463
Kapoor R, Giri B, Mukerji KG (2002b) Mycorrhization of coriander (Coriandrum sativum L.) to enhance the concentration and quality of essential oil. J Sci Food Agric 82:339–342
Kapoor R, Giri B, Mukerji KG (2004) Improved growth and essential oil yield and quality in Foeniculum vulgare mill on mycorrhizal inoculation supplemented with P-fertilizer. Bioresour Technol 93:307–311
Kapoor R, Chaudhary V, Bhatnagar AK (2007) Effects of arbuscular mycorrhiza and phosphorus application on artemisinin concentration in Artemisia annua L. Mycorrhiza 17:581–587
Karagiannidis N, Thomidisa T, Lazari D, Filotheou EP, Karagiannidou C (2011) Effect of three Greek arbuscular mycorrhizal fungi in improving the growth, nutrient concentration, and production of essential oils of oregano and mint plants. Sci Hortic 129:329–334
Khaosaad T, Vierheilig H, Nell M, Zitterl-Eglseer K, Novak J (2006) Arbuscular mycorrhiza alter the concentration of essential oils in oregano (Origanum sp., Lamiaceae). Mycorrhiza 16:443–446
Koide RT (1991) Nutrient supply, nutrient demand and plant response to mycorrhizal infection. New Phytol 117:365–386
Koide RT, Schreiner RP (1992) Regulation of the vesicular-arbuscular mycorrhizal symbiosis. Annu Rev Plant Physiol Plant Mol Biol 43:557–581
Krishna H, Singh S, Sharma RR, Khawale RN, Grover M, Patel VB (2005) Biochemical changes in micropropagated grape (Vitis vinifera L.) plantlets due to arbuscular-mycorrhizal fungi (AMF) inoculation during ex vitro acclimatization. Sci Hort 106(4):554–567
Lapeyrie F (1988) Oxalate synthesis from soil bicarbonate by fungus Paxillus involutus. Plant Soil 110:3–8
Leake J, Johnson D, Donnelly D, Muckle G, Boddy L, Read (2004) Networks of power and influence: the role of mycorrhizal mycelium in controlling plant communities and agroecosystem functioning. Can J Bot 82:1016–1045
Lee J, Scagel CF (2009) Chicoric acid found in basil (Ocimum basilicum L.) leaves. Food Chem 115(2):650–656
Li CX (2003a) Effect of vesicular-arbuscular mycorrhizal fungi on production of Ginseng. J Chin Med Mater 26(7):475–476
Li CX (2003b) Effects of infecting vesicular-arbuscular mycorrhiza on growth and development of Coix Lachryma-jobi L. J Shanxi Agric Univ 23(4):351–353
Liu T, He XL (2008) Research on the formation course of arbuscular mycorrhizae from Astragalus membranaceus (Fisch.) Bunge seedlings. J Hebei For Orc Res 23(3):311–314
Liu SL, He XL (2009) Effects of AM fungi on growth of Glycyrrhiza inflata Bat under water stress. J Nucl Agric Sci 23(4):692–696
Liu JN, Wu LJ, Wei SL, Xiao X, Su CX, Jiang P, Song ZB, Wang T, Yu ZL (2007) Effects of arbuscular mycorrhizal fungi on the growth, nutrient uptake and glycyrrhizin production of licorice (Glycyrrhiza uralensis Fisch). Plant Growth Regul 52(1):29–39
Loomis WD, Corteau R (1972) Essential oil biosynthesis. Rec Adv Phytochem 6:147–185
Lu YQ, He XL (2005) Effects of AM fungi on the chemical composition and growth amount of Atractylodes macrocephala koidz seedling on different N levels. J Hebei Univ 25(6):650–653
Lu YQ, He XL (2008) Effects of AM fungi on photosynthetic pigment of Atractylodes macrocephala under different nitrogen levels. Acta Agric Bor Occi Sin 17(4):314–321
Lu YQ, Cui Y, He XL (2008a) Effects of AM fungi on biomass and nitrogen content of Atractylodes macrocephala under different nitrogen levels. J Henan Agric Sci 4:94–96
Lu YQ, He XL, Li LZ (2008b) Effects of AM fungi on leaf protective enzymes of Atractrlodes macrocephala under different nitrogen levels. Hubei Agric Sci 47(6):659–660
Lu YQ, Wang DX, Lu XL, Li LM, Li Y, He XL (2011) Effects of AM fungi on physiological character and nutritional component of Atractylodes macrocephala under different N levels. Acta Bot Bor Occi Sin 31(2):351–356
Lu FC, Lee CY, Wang CL (2015) The influence of arbuscular mycorrhizal fungi inoculation on yam (Dioscorea spp.) tuber weights and secondary metabolite content. Peer J 3:e1266
Ma J, He XL, Jiang ZM, Wang LY (2009) Influence of soil factors on arbuscular mycorrhizal fungal colonization of Salvia miltiorrhiza. Acta Agric Bor Occi Sin 18(5):194–198
Maier W, Schmidt J, Wray V, Walter MH, Strack D (1999) The arbuscular mycorrhizal fungus, Glomus intraradices, induces the accumulation of cyclohexenone derivatives in tobacco roots. Planta 207:620–623
Mamta G, Rahi P, Pathania V, Gulati A, Singh B, Bhanwra RK, Tewari R (2012) Comparative efficiency of phosphate-solubilizing bacteria under greenhouse conditions for promoting growth and aloin-A content of Aloe barbadensis. Arch Agron Soil Sci 58(4):437–449
Mandal S, Evelin H, Giri B, Singh VP, Kapoor R (2013) Arbuscular mycorrhiza enhances the production of stevioside and rebaudioside-A in Stevia rebaudiana via nutritional and non-nutritional mechanisms. Appl Soil Ecol 72:187–194
Mandal A, Mandal S, Park MH (2014) Genome-wide analyses and functional classification of proline repeat-rich proteins: potential role of eIF5A in eukaryotic evolution. PLoS One 9(11):e111800
Mandal S, Upadhyay S, Singh VP, Kapoor R (2015) Enhanced production of steviol glycosides in mycorrhizal plants: a concerted effect of arbuscular mycorrhizal symbiosis on transcription of biosynthetic genes. Plant Physiol Biochem 89:100–106
Marschner H (1995) Mineral nutrition of higher plants, 2nd edn. Elsevier Science, San Diego
Marschner H (1998) Mineral nutrition of higher plants. Academic, London
McGarvey DJ, Croteau R (1995) Terpenoid metabolism. Plant Cell 7(7):1015
Meng JJ, He XL (2011) Effects of AM fungi on growth and nutritional contents of Salvia miltiorrhiza Bge. under drought stress. J Agric Univ Hebei 34(1):51–61
Morone Fortunato I, Avato P (2008) Plant development and synthesis of essential oils in micropropagated and mycorrhiza inoculated plants of Origanum vulgare L. ssp. hirtum (Link) Ietswaart. Plant Cell Tissue Organ 93:139–149
Nell M, Vötsch M, Vierheilig H, Steinkellner S, Zitterl-Eglseer K, Franz C, Novak J (2009) Effect of phosphorus uptake on growth and secondary metabolites of garden (Salvia officinalis L.). J Sci Food Agric 89:1090–1096
Nell M, Wawrosh C, Steinkellner S, Vierheilig H, Kopp B, Lössl A, Franz C, Novak J, Zitterl-Eglseer K (2010) Root solonization by symbiotic arbuscular mycorrhizal fungi increases sesquiterpenic acid concentrations in Valeriana of ficinalis L. Planta Med 76:393–398
Pan PL, Chen DQ, Chen YT, Zhou FM (2008) The research on the sift and germinate of AM FUNGI spore of Ophiopogon japonicas. Mod Chin Med 10(10):13–14
Pandey DK, Banik RM (2009) The influence of dual inoculation with Glomus mossae and Azotobacter on growth and barbaloin content of Aloe vera. Am Eu J Sust Agric 3(4):703–714
Pandey DK, Banik RM, Dey A, Panwar J (2014) Improved growth and colchicines concentration in Gloriosa superb in mycorrhizal inoculation supplemented with phosphorus – fertilizer. Afr J Tradit Complement Altern Med 11(2):439–446
Peng S, Eissenstat DM, Graham JH, Williams K, Hodge NC (1993) Growth depression in mycorrhizal citrus at high-phosphorus supply: analysis of carbon costs. Plant Physiol 101:1063–1071
Petersen M, Simmonds MSJ (2003) Rosmarinic acid. Phytochemistry 62:121–125
Phillipson JD (1999) New drugs from nature—It could be yew. Phytother Res 13(1):2–8
Pozo MJ, Azcón-Aguilar C (2007) Unraveling mycorrhiza-induced resistance. Curr Opin Plant Biol 10(4):393–398
Prasad A, Kumar S, Khaliq A, Pandey A (2011) Heavy metals and arbuscular mycorrhizal (AM) fungi can alter the yield and chemical composition of volatile oil of sweet basil (Ocimum basilicum L.). Biol Fertil Soils 47(8):853–861
Qi GH, Zhang LP, Yang WL, Lu XR, Li CL (2002) Effects of arbuscular mycorrhizal fungi on growth and disease resistance of replanted ginkgo (Ginkgo biloba L.) seedlings. J Hebei For Orch Res 17(1):58–61
Qi GH, Zhang LP, Yang WL, Lv GY (2003) The effects of abruscular mycorrhiza fungi on ginkgo (Ginkgo biloba L.) in the field. Hebei Fruits 19(1):40–42
Rajan SK, Reddy BJD, Bagyaraj DJ (2000) Screening of arbuscular mycorrhizal fungi for their symbiotic efficiency with Tectona grandis. Forest Ecol Manag 126(2):91–95
Rapparini F, Llusia J, Penuelas J (2008) Effect of arbuscular mycorrhizal (AM) colonization on terpene emission and content of Artemisia annua L. Plant Biol 10:108–122
Rasouli-Sadaghianil MH, Hassani A, Barin M, Danesh YR, Sefidkon F (2010) Effects of arbuscular mycorrhizal (AM) fungi on growth, essential oil production and nutrients uptake in basil. J Med Plant Res 4(21):2222–2228
Rastogi PR, Meharotra BN (1990) (eds) In: Compendium of Indian medicinal plants, publications and information directorate, CSIR, New Delhi, vol.l, p 339
Redecker D, Morton JB, Bruns TD (2000) Ancestral lineages of arbuscular mycorrhizal fungi (Glomales). Mol Phylogenet Evol 14:276–284
Ren JH, Liu RX, Li YL (2007) Study on arbuscular mycorrhizae of Panax notoginseng. Microbiology 34(2):224–227
Ren JH, Zhang JF, Liu RX, Li YQ (2008) Study on arbuscular mycorrhizae in Taxus chinensis var. mairei. Acta Bot Bor Occi Sin 28(7):1468–1473
Roepke J, Salim V, Wu M, Thamm AM, Murata J, Ploss K, Wilhelm B, De Luca V (2010) Vinca drug components accumulate exclusively in leaf exudates of Madagascar periwinkle. Proc Natl Acad Sci 107(34):15287–15292
Rojas-Andrade R, Cerda-GarcÍa-Rojas CM, FrÍas-Hernández JT, Dendooven L, Olalde-Portugal V, Ramos-Valdivia AC (2003) Changes in the concentration of trigonelline in a semi-arid leguminous plant (Prosopis laevigata) induced by an arbuscular mycorrhizal fungus during the presymbiotic phase. Mycorrhiza 13:49–52
Sailo GS, Bagyaraj DJ (2005) Influence of different AM-fungi on the growth, nutrition and forskolin content of Coleus forskohlii. Mycol Res 109(7):795–798
Schüßler A, Schwarzott D, Walker C (2001) A new fungal phylum, the Glomeromycota, phylogeny and evolution. Mycol Res 105:1413–1421
Singh R, Soni SK, Kalra A (2013) Synergy between Glomus fasciculatum and a beneficial Pseudomonas in reducing root diseases and improving yield and forskolin content in Coleus forskohlii Briq. under organic field conditions. Mycorrhiza 23:35–44
Shah V, Bhat SV, Bajwa BS, Domacur H, De SNJ (1980) The occurrence of forskolin in Labiatae. Planta Med 39:183–185
Shen XL, Guo QS, Liu ZY, Zhu GS, Liu YX (2011) Colonization progress of arbuscular mycorrhizae on tissue-cultured plantlets of Pinellia ternata. Chin J Chin Mater Med 36:93–96
Shibata K, Iwata S, Nakamura M (1923) Baicalin, a new flavone-glucuronic acid compound from the roots of Scutellaria baicalensis. Acta Phytochim 1:105–139
Sieverding E, Friedrichsen J, Suden W (1991) Vesicular-arbuscular mycorrhiza management in tropical agrosystems. Sonderpublikation der GTZ (Germany)
Silva MFD, Pescador R, Rebelo RA, Stürmer SL (2008) The effect of arbuscular mycorrhizal fungal isolates on the development and oleoresin production of micropropagated Zingiber officinale. Braz J Plant Physiol 20(2):119–130
Silva FA, Ferreira MR, Soares LA, Sampaio EV, Maia LC (2014) Arbuscular mycorrhizal fungi increase gallic acid production in leaves of field grown Libidibia ferrea (Mart. ex Tul.) LP Queiroz. J Med Plant Res 8(36):1110–1115
Smith SE, Read DJ (1997) Mycorrhizal symbiosis. Academic, London
Smith SE, Read DJ (2008) Mycorrhizal symbiosis, 3rd edn. Academic, London
Smith SE, Smith FA, Jakobsen I (2004) Functional diversity in arbuscular mycorrhizal (AM) symbioses: the contribution of the mycorrhizal P uptake pathway is not correlated with mycorrhizal responses in growth or total P uptake. New Phytol 162:511–524
de Sousa OM, da Silva Campos MA, de Albuquerque UP, da Silva FSB (2013) Arbuscular mycorrhizal fungi (AMF) affects biomolecules content in Myracrodruon urundeuva seedlings. Ind Crop Prod 50:244–247
Strack D, Fester T, Hause B, Schliemann W, Walter MH (2003) Arbuscular mycorrhiza: biological, chemical, and molecular aspects. J Chem Ecol 29(9):1955–1979
Suzuki Y (2002, May 29) In Current status and future directions of alternative medicine, WHO, Geneva, Switzerland
Swami Tirtha SS (1998) In: Uniyal RC et al (eds) Ayurvedic Encyclopedia, Natural Secrets to Healing, Prevention, and Longevity: history of Ayurvedic Tree, 1st edn. New Delhi, Sai Satguru Publications
Szakiel A, Pączkowski H (2011a) Influence of environmental biotic factors on the content of saponins in plants. Phytochem Rev 10:493–502
Szakiel A, Pączkowski H (2011b) Influence of environmental abiotic factors on the content of saponins in plants. Phytochem Rev 10:471–491
Burni T, Saadia N, Tabassum Y, Sakina B (2013) Arblscular mycorrhizal stuidies in “Aloe vera (l). burm. f.” biologically active and potential medicinal plant. Wudpecker J Agric Res 2(1):039–042
Tang W, Eisenbrand G (1992) In: Chinese drugs of plant origin, SpingerVerlag, Berlin, p 127
Teng HR, He XL (2005) Effects of different AM fungi and N levels on the flavonoid content of Bupleuruin scorzonerifolium Willd. J Shanxi Agric Sci 4:53–54
Torelli A, Trotta A, Acerbi L, Arcidiacono G, Berta G, Branca C (2000) IAA and ZR content in leek (Allium porrum L.), as influenced by P nutrition and arbuscular mycorrhizae, in relation to plant development. Plant Soil 226(1):29–35
Toussaint JP (2007) Investigating physiological changes in the aeria parts of AM plants: what do we know and where should we be heading? Mycorrhiza 17:349–353
Toussaint JP, St-Arnaud M, Charest C (2004) Nitrogen transfer and assimilation between the arbuscular mycorrhizal fungus Glomus intraradices Schenck & Smith and Ri T-DNA roots of Daucus carota L. in an in vitro compartmented system. Can J Microbiol 50:251–260
Toussaint JP, Smith FA, Smith SE (2007) Arbuscular mycorrhizal fungi can induce the production of phytochemicals in sweet basil irrespective of phosphorus nutrition. Mycorrhiza 17:291–297
Verpoorte R (1999) Secondary metabolism. In: Verpoorte R, Alfermann AW (eds) Metabolic engineering of plant secondary metabolism. Klumer Academic Publishers, Dordrecht, pp 1–29
Volpin H, Elkind Y, Okon Y, Kapulnik Y (1994) A vesicular arbuscular mycorrhizal fungus (Glomus intraradices) induces a defense response in alfalfa roots. Plant Physiol 104:683–689
Wang LY, He XL (2009) The resource and spatio-temporal distribution of AM fungi from Salvia miltiorrhiza in Anguo. J Agric Univ Hebei 32(6):73–79
Wang Q, Li HQ, Du YR, Li Y, Li HW (1998) Isolation and identification of VA mycorrhizal fungi on Radix gentianae. Biotechnology 8(2):19–22
Wang Q, He XL, Chen TS, Dou WF (2006) Ecological research of arbuscular mycorrhizal fungi in rhizosphere of Puerraria lobata. J Hebei Univ 26(4):420–425
Wang DX, Lu YQ, He XL (2010) Effects of AM fungi on growth and physiological characters of Atractylodes macrocephala under different P-applied levels. Acta Bot Bor Occi Sin 30(1):136–142
Warrier PK, Nambiar VPK, Ramankutti C (1996) (eds), In Indian medicinal plants: a compendium of 500 species, Orient Longmann, Hyderabad, vol 4. p 409
Wei GT, Wang HG (1989) Effects of VA mycorrhizal fungi on growth, nutrient uptake and effective compounds in Chinese medicinal herb Datura stramonium L. Sci Agric Sin 22(5):56–61
Wei GT, Wang HG (1991) Effect of vesicular-arbuscular mycorrhizal fungi on growth, nutrient uptake and synthesis of volatile oil in Schizonepeta tenuifolia Briq. Chin J Chin Mater Med 16(3):139–142
Wiermann R (1981) Secondary plant products and cell and tissue differentiation. In: The biochemistry of plants, vol. 7. Academic, New York, pp 85–116
Wink M (1997) Compartmentation of secondary metabolites and xenobiotics in plant vacuoles. Adv Bot Res 25:141–169
Wink M (1999) Introduction: biochemistry, role and biotechnology of secondary metabolites. In: Wink M (ed) Biochemistry of plant secondary metabolism. Sheffield Academic Press Ltd, Sheffield, pp 1–16
Wu QC, Wei QA (2008) Arbuscular mycorrhizae of Ginkgo biloba and its correlation with soil available phosphorus. J Yangtze Univ 5(3):49–52
Wu QS, Liu W, Zhai HF, Ye XF, Zhao LJ (2010) Influences of AM fungi on growth and root antioxidative enzymes of Trifoliate orange seedlings under salt stress. Acta Agric Univ Jiangxiensis 32(4):759–762
Xing XK, Li Y, Yolande D (2000) Ten species of vAM fungi in five ginseng fields of Jilin province. J Jilin Agric Univ 22(2):41–46
Xing XK, Li Y, Wang Y, Zhang MP (2003) Foundation of dual cultural system of ginseng VA mycorrhiza fungi. J Jilin Agric Univ 25(2):154–157
Xiao WJ, Yang G, Chen ML, Guo LP, Wang M (2011) AM and its application in plant disease prevention of Chinese medicinal herbs cultivation. Chin J Chin Med 36(3):252–257
Yang G, Guo LP, Huang LQ, Chen M (2008) Inoculation methods of AM fungi in medicinal plant. Resour Sci 30(5):778–785
Yang Y, Ou X, Yang G, Xia Y, Chen M, Guo L, Liu D (2017) Arbuscular mycorrhizal fungi regulate the growth and phyto-active compound of Salvia miltiorrhiza seedlings. Appl Sci 7(1):68
Yadav K, Aggarwal A, Singh N (2013) Arbuscular mycorrhizal fungi (AMF) induced acclimatization, growth enhancement and colchicine content of micropropagated Gloriosa superba L. plantlets. Ind Crop Prod 45:88–93
Yu Y, Yu T, Wang Y, Yan XF (2010) Effect of inoculation time on camptothecin content in arbuscular mycorrhizal Camptotheca acuminate seedlings. Chin J Plant Ecol 34(6):687–694
Zeng Y, Guo LP, Hang LQ, Zhou J, Sun YZ (2007) AM and its application in TCM cultivation. World Sci Technol/Moder TCM Mater Med 9(6):83–87
Zhang MC, Jing YJ, Ma J (1990) The changing of microbial ecological types after the improvement of ginseng soil. J Jilin Agric Univ 12(4):42–46
Zhang Y, Xie LY, Xiong BQ, Zeng M, Yu D (2004) Correlation between the growth of arbuscular mycorrhizal fungi in the rhizosphere and the flavonoid content in the root of Ginkgo biloba. Mycosystema 23(1):133–138
Zhang J, Liu DH, Guo LP, Jin H, Zhou J, Yang G (2010) Effects of four AM fungi on growth and essential oil composition in rhizome of Atractylodes lancea. World Sci Technol/Moder TCM Mater Med 12(5):779–782
Zhang J, Liu DH, Guo LP, Jin H, Yang G, Zhou J (2011) Effects of arbuscular mycorrhizae fungi on biomass and essential oil in rhizome of Atractylodes lancea in different temperatures. Chin Tradit Herb Drugs 42(2):372–375
Zhao JL, He XL (2011) Effects of AM fungi on drought resistance and content of chemical components in Angelica dahurica. Acta Agric Bor Occi Sin 20(3):184–189
Zhao X, Wang BW, Yan XF (2006) Effect of arbuscular mycorrhiza on camptothecin content in Camptotheca acuminate seedlings. Acta Ecol Sin 26(4):1057–1062
Zhao PJ, An F, Tang M (2007) Effects of arbuscular mycorrhiza fungi on drought resistance of Forsythia suspense. Acta Bot Bor Occi Sin 27(2):396–399
Zhao JL, Deng HY, He XL (2009) Effects of AM fungi on the quality of trueborn Angelica dahurica from Hebei province. Acta Agric Boreali-Sin 24:299–302
Zhou JH, Fan JH (2007) Effects of AM fungi on the berberine content in Phellodendron chinense seedings. North Hortic 12:25–27
Zhou N, Xia CL, Jiang B, Bai ZC, Liu GN, Ma XK (2009) Arbuscular mycorrhiza in Paris polyphylla var. yunnanensis. Chin J Chin Med 34(14):1768–1772
Zhou N, Zou L, Wang GZ, Jiang B (2010) Primary explore to relation of arbuscular mycorrhizae and its secondary metabolite steroidal saponin in Paris polyphylla. Chin J Exp Tradit Med Formulae 16(16):85–88
Zubek S, Stojakowska A, Anielska T, Turnau K (2010) Arbuscular mycorrhizal fungi alter thymol derivative contents of Inula ensifolia L. Mycorrhiza 20:497–504
Zubek S, Mielcarek S, Turnau K (2012) Hypericin and pseudohypericin concentrations of a valuable medicinal plant Hypericum perforatum L. are enhanced by arbuscular mycorrhizal fungi. Mycorrhiza 22:149–156
Zubek S, Błaszkowski J, Seidler-Łożykowska K, Bąba W, Mleczko P (2013) Arbuscular mycorrhizal fungi abundance, species richness and composition under the monocultures of five medicinal plants. Acta Sci Pol-Hortoru 12:127–141
Zubek S, Rola K, Szewczyk A, Majewska ML, Turnau K (2015) Enhanced concentrations of elements and secondary metabolites in Viola tricolor L. induced by arbuscular mycorrhizal fungi. Plant Soil 390(1–2):129–142
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Pandey, D.K., Kaur, P., Dey, A. (2018). Arbuscular Mycorrhizal Fungi: Effects on Secondary Metabolite Production in Medicinal Plants. In: Gehlot, P., Singh, J. (eds) Fungi and their Role in Sustainable Development: Current Perspectives. Springer, Singapore. https://doi.org/10.1007/978-981-13-0393-7_28
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