Abstract
Salicylic acid is extracted from willow and Rosaceae, which was modified to aspirin to reduce the irritation of the digestive tract. Low-dose aspirin (75–300 mg/day) has antiplatelet aggregation effect, middle dose of aspirin (0.5–3 g/day) has antipyretic analgesic effects, and high doses of aspirin (more than 4 g/day) has anti-inflammatory and antirheumatic effects. However, aspirin also has adverse effects, mainly gastrointestinal symptoms such as nausea, vomiting, upper abdominal discomfort or pain. As a nonsteroidal anti-inflammatory drug (NSAID), aspirin was listed in July 1899 and has been used for more than 100 years. It is one of the three classic drugs in the history of medicine and the world’s most widely used antipyretic, analgesic and anti-inflammatory drugs.
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© 2018 Springer Nature Singapore Pte Ltd. and People's Medical Publishing House, PR of China
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Chen, YC., Qiang, GF., Du, GH. (2018). Salicylic Acid. In: Natural Small Molecule Drugs from Plants. Springer, Singapore. https://doi.org/10.1007/978-981-10-8022-7_76
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DOI: https://doi.org/10.1007/978-981-10-8022-7_76
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