Abstract
Endoscopic retrograde cholangiopancreatography (ERCP) is now widely used both in the diagnosis and treatment of a variety of pancreatic diseases. With advances in techniques, pancreatic endotherapy has been gaining popularity in the treatment of a myriad of pancreatic disorders including chronic pancreatitis, pancreatic duct stones, pancreatic duct leaks or disruptions, drainage of pseudocysts, and the prevention of pancreatitis following ERCP. The most common pancreatic endotherapeutic procedures are pancreatic sphincterotomy and stenting. Pancreatic sphincterotomy is a high-risk and technically demanding procedure. Stenting of the main pancreatic duct is particularly useful in relieving ductal obstruction, often in the setting of refractory pain from strictures, stones, or papillary stenosis. The role of pancreatic stents in preventing ERCP-induced pancreatitis has also been established. Additionally, stenting of the minor papilla has been used in the treatment of symptomatic pancreas divisum due to a stenotic minor papilla. Pancreatic duct stricture dilation is another important procedure for obstructive pancreatic disorders. The indications and techniques related to pancreatic sphincterotomy, stenting, and pancreatic duct dilation are discussed.
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References
Stimec B, Bulajic M, Korneti V, et al. Ductal morphometry of ventral pancreas in pancreas divisum. Comparison between clinical and anatomical results. Ital J Gastroenterol. 1996;28(2):76–80.
Delhaye M, Cremer M. Clinical significance of pancreas divisum. Acta Gastroenterol Belg. 1992;55(3):306–13.
Bertin C, Pelletier AL, Vullierme MP, et al. Pancreas divisum is not a cause of pancreatitis by itself but acts as a partner of genetic mutations. Am J Gastroenterol. 2012;107(2):311–7.
Adibelli ZH, Adatepe M, Isayeva L, et al. Pancreas divisum: a risk factor for pancreaticobiliary tumors - an analysis of 1628 MR cholangiography examinations. Diagn Interv Imaging. 2017;98(2):141–7.
Misra SP, Gulati P, Thorat VK, et al. Pancreaticobiliary ductal union in biliary diseases. An endoscopic retrograde cholangiopancreatographic study. Gastroenterology. 1989;96(3):907–12.
Kimura K, Ohto M, Saisho H, et al. Association of gallbladder carcinoma and anomalous pancreaticobiliary ductal union. Gastroenterology. 1985;89(6):1258–65.
Sameshima Y, Muto Y, Uchimura M, et al. Clinicopathological study of the gallbladder in congenital dilatation of the bile duct--with special reference to the association with cancer. Nihon Shokakibyo Gakkai Zasshi. 1982;79(5):1129–36.
Jones SN, Lees WR, Frost RA. Diagnosis and grading of chronic pancreatitis by morphological criteria derived by ultrasound and pancreatography. Clin Radiol. 1988;39(1):43–8.
Bozkurt T, Braun U, Leferink S, et al. Comparison of pancreatic morphology and exocrine functional impairment in patients with chronic pancreatitis. Gut. 1994;35(8):1132–6.
Axon AT, Classen M, Cotton PB, et al. Pancreatography in chronic pancreatitis: international definitions. Gut. 1984;25(10):1107–12.
Drake DH, Fry WJ. Ductal drainage for chronic pancreatitis. Surgery. 1989;105(2 Pt 1):131–40.
Bradley EL 3rd. Pancreatic duct pressure in chronic pancreatitis. Am J Surg. 1982;144(3):313–6.
Reber HA, Karanjia ND, Alvarez C, et al. Pancreatic blood flow in cats with chronic pancreatitis. Gastroenterology. 1992;103(2):652–9.
Delhaye M, Vandermeeren A, Baize M, et al. Extracorporeal shock-wave lithotripsy of pancreatic calculi. Gastroenterology. 1992;102(2):610–20.
Kang MJ, Jang JY, Chang YR, et al. Revisiting the concept of lymph node metastases of pancreatic head cancer: number of metastatic lymph nodes and lymph node ratio according to N stage. Ann Surg Oncol. 2014;21(5):1545–51.
Niederau C, Grendell JH. Diagnosis of pancreatic carcinoma. Imaging techniques and tumor markers. Pancreas. 1992;7(1):66–86.
DeWitt J, Misra VL, Leblanc JK, et al. EUS-guided FNA of proximal biliary strictures after negative ERCP brush cytology results. Gastrointest Endosc. 2006;64(3):325–33.
Adamek HE, Albert J, Breer H, et al. Pancreatic cancer detection with magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography: a prospective controlled study. Lancet. 2000;356(9225):190–3.
Deviere J, Bueso H, Baize M, et al. Complete disruption of the main pancreatic duct: endoscopic management. Gastrointest Endosc. 1995;42(5):445–51.
Kozarek RA, Ball TJ, Patterson DJ, et al. Transpapillary stenting for pancreaticocutaneous fistulas. J Gastrointest Surg. 1997;1(4):357–61.
Kozarek RA, T. L. Endoscopic treatment of chronic pancreatitis: an alternative to surgery? Dig Surg. 1996;13:90.
Wolfsen HC, Kozarek RA, Ball TJ, et al. Pancreaticoenteric fistula: no longer a surgical disease? J Clin Gastroenterol. 1992;14(2):117–21.
Seewald S, Brand B, Groth S, et al. Endoscopic sealing of pancreatic fistula by using N-butyl-2-cyanoacrylate. Gastrointest Endosc. 2004;59(4):463–70.
Turner BG, Brugge WR. Diagnostic and therapeutic endoscopic approaches to intraductal papillary mucinous neoplasm. World J Gastrointest Surg. 2010;2(10):337–41.
Sai JK, Nobukawa B, Matsumura Y, et al. Pancreatic duct lavage cytology with the cell block method for discriminating benign and malignant branch-duct type intraductal papillary mucinous neoplasms. Gastrointest Endosc. 2013;77(5):726–35.
Yamaguchi T, Hara T, Tsuyuguchi T, et al. Peroral pancreatoscopy in the diagnosis of mucin-producing tumors of the pancreas. Gastrointest Endosc. 2000;52(1):67–73.
Yasuda K, Sakata M, Ueda M, et al. The use of pancreatoscopy in the diagnosis of intraductal papillary mucinous tumor lesions of the pancreas. Clin Gastroenterol Hepatol. 2005;3(7 Suppl 1):S53–7.
Furukawa T, Tsukamoto Y, Naitoh Y, et al. Differential diagnosis between benign and malignant localized stenosis of the main pancreatic duct by intraductal ultrasound of the pancreas. Am J Gastroenterol. 1994;89(11):2038–41.
Dumonceau JM, Delhaye M, Tringali A, et al. Endoscopic treatment of chronic pancreatitis: European Society of Gastrointestinal Endoscopy (ESGE) clinical guideline. Endoscopy. 2012;44(8):784–800.
Somogyi L, Chuttani R, Croffie J, et al. Biliary and pancreatic stents. Gastrointest Endosc. 2006;63(7):910–9.
Ikenberry SO, Sherman S, Hawes RH, et al. The occlusion rate of pancreatic stents. Gastrointest Endosc. 1994;40(5):611–3.
Bakman YG, Safdar K, Freeman ML. Significant clinical implications of prophylactic pancreatic stent placement in previously normal pancreatic ducts. Endoscopy. 2009;41(12):1095–8.
Lawrence C, Cotton PB, Romagnuolo J, et al. Small prophylactic pancreatic duct stents: an assessment of spontaneous passage and stent-induced ductal abnormalities. Endoscopy. 2007;39(12):1082–5.
Ziebert JJ, DiSario JA. Dilation of refractory pancreatic duct strictures: the turn of the screw. Gastrointest Endosc. 1999;49(5):632–5.
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Sun, CK. (2018). ERCP for Pancreatic Disorders. In: Lai, KH., Mo, LR., Wang, HP. (eds) Biliopancreatic Endoscopy. Springer, Singapore. https://doi.org/10.1007/978-981-10-4367-3_9
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DOI: https://doi.org/10.1007/978-981-10-4367-3_9
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