Abstract
Effects of energy drinks (ED) are attributed to the combination of their three main ingredients: caffeine, taurine, and glucose. The primary objective of this study was to evaluate the main effects and interactions of these ingredients on mood, reaction time during a working memory task and to identify the specific brain regions involved using functional Magnetic Resonance Images (fMRI). In a double-blind, mixed factor and repeated measurement design, 12 healthy volunteers (6 male, 6 females) received one of four treatments (200 mg caffeine/0 mg taurine, 0 mg caffeine/2000 mg taurine, 200 mg caffeine/2000 mg taurine, 0 mg caffeine/0 mg taurine) on each of four separated days. Between-participants treatment was a glucose (11 g of glucose) or placebo (3 g of Stevia). All participants were evaluated with a mood questionnaire in three times and underwent a working memory task, where reaction time was registered, while fMRI were acquired. Functional images were analyzed considering treatment and task difficulty as within-participants in a repeated measurements general linear model. Our results shown that glucose had the most consistent effects on mood, decreasing feelings of tension, depression, anger and fatigue and increasing feeling of vigor. However, reaction time had significant differences only for task difficulty without interactions due to the treatment or glucose intake. Significant activations of brain regions were located at frontal, temporal and cingulate gyrus but main effects and interactions with treatment and glucose were explained only for the task difficulty.
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References
“New Market Research Report: Energy Drinks in Mexico,” ed: SyndiGate Media Inc., 2016
K. A. Sepkowitz, “Energy drinks and caffeine-related adverse effects,” JAMA, vol. 309, pp. 243-4, Jan 16 2013.
S. Attila and B. Çakir, “Energy-drink consumption in college students and associated factors,” Nutrition, vol. 27, pp. 316-322, 2011
J. E. James and P. J. Rogers, “Effects of caffeine on performance and mood: withdrawal reversal is the most plausible explanation,” Psychopharmacology, vol. 182, pp. 1-8, 2005.
F. Koppelstaetter, T. D. Poeppel, C. M. Siedentopf, A. Ischebeck, C. Kolbitsch, F. M. Mottaghy, et al., “Caffeine and cognition in functional magnetic resonance imaging,” J Alzheimers Dis, vol. 20 Suppl 1, pp. S71-84, 2010
K. Ito, M. Arko, T. Kawaguchi, M. Kuwahara, and H. Tsubone, “The effect of subacute supplementation of taurine on spatial learning and memory,” Experimental Animals, vol. 58, pp. 175-180, 2009
F. Junyent, L. De Lemos, J. Utrera, S. Paco, F. Aguado, A. Camins, et al., “Content and traffic of taurine in hippocampal reactive astrocytes,” Hippocampus, vol. 21, pp. 185-197, 2011
B. P. Vohra and X. Hui, “Improvement of impaired memory in mice by taurine,” Neural Plast, vol. 7, pp. 245-59, 2000
M. B. Gilsenan, E. A. de Bruin, and L. Dye, “The influence of carbohydrate on cognitive performance: a critical evaluation from the perspective of glycaemic load,” Br J Nutr, vol. 101, pp. 941-9, Apr 2009
G. E. Giles, C. R. Mahoney, T. T. Brunye, A. L. Gardony, H. A. Taylor, and R. B. Kanarek, “Differential cognitive effects of energy drink ingredients: caffeine, taurine, and glucose,” Pharmacol Biochem Behav, vol. 102, pp. 569-77, Oct 2012
P. F. del Consumidor, “Bebidas saborizadas, hidratantes y para deportistas,” Revista del consumidor, vol. 281, 2000
D. M. McNair, M. Lorr, and L. F. Droppleman, Profile of mood states: Educational and Industrial Testing Service San Diego, CA, 1981
J. L. Donovan and C. L. DeVane, “A primer on caffeine pharmacology and its drug interactions in clinical psychopharmacology,” Psychopharmacol Bull, vol. 35, pp. 30-48, Summer 2001
L. E. Nystrom, T. S. Braver, F. W. Sabb, M. R. Delgado, D. C. Noll, and J. D. Cohen, “Working memory for letters, shapes, and locations: fMRI evidence against stimulus-based regional organization in human prefrontal cortex,” Neuroimage, vol. 11, pp. 424-46, May 2000.
M. McFarquhar, S. McKie, R. Emsley, J. Suckling, R. Elliott, and S. Williams, “Multivariate and repeated measures (MRM): A new toolbox for dependent and multimodal group-level neuroimaging data,” NeuroImage, vol. 132, pp. 373-389, 2016
D. E. Nee, J. W. Brown, M. K. Askren, M. G. Berman, E. Demiralp, A. Krawitz, et al., “A meta-analysis of executive components of working memory,” Cereb Cortex, vol. 23, pp. 264-82, Feb 2013
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Martínez-Torres, C., Calvillo, M., Romero-Rebollar, C., Martínez-Cancino, D., Flores-Leal, M., Jiménez-Angeles, L. (2017). Main Effects of Energy Drinks on Mood, Reaction Time and Brain Regions. In: Torres, I., Bustamante, J., Sierra, D. (eds) VII Latin American Congress on Biomedical Engineering CLAIB 2016, Bucaramanga, Santander, Colombia, October 26th -28th, 2016. IFMBE Proceedings, vol 60. Springer, Singapore. https://doi.org/10.1007/978-981-10-4086-3_158
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DOI: https://doi.org/10.1007/978-981-10-4086-3_158
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