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Severe Mental Illness and Reproductive Health

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Mental Health and Illness of Women

Part of the book series: Mental Health and Illness Worldwide ((MHIW))

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Abstract

Severe mental illness (SMI) during pregnancy and the postpartum has the potential to impact negatively on the well-being of the mother, the mother-infant dyad, and her family. Untreated SMI can lead to poor attendance to antenatal care, impair mother-infant attachment, and, in rare cases, lead to suicide and infanticide. The wider usage of newer antipsychotics, deinstitutionalization, lessened stigma, and greater opportunities for social interaction have allowed many women with preexisting severe mental illness to embrace the possibility of, and plan for, parenthood. However, mothers with SMI in general continue to experience multifaceted risks such as unplanned pregnancies, obstetric complications, comorbid substance abuse, poor social support, and interpersonal violence which impact on outcomes and stretch available health resources. Mental health services and clinicians need to be aware that their female patients with SMI of reproductive age can and often do become pregnant and that preventative strategies (preconception counseling) for those who plan to become pregnant and contingent strategies (timely referral pathways and specialist consultations) for those who have unplanned pregnancies should become part of their core business. Obstetric and child health services need to work in conjunction with mental health services in identifying the needs of high-risk women, who may develop index episodes of severe mental illness during their perinatal period, particularly in the postpartum. As psychotropic medication is the mainstay of treatment for women with SMI, a necessary impetus is on the need for robust safety data in pregnancy and breastfeeding, so the woman and her family can make informed choices. Equally important though are the relational and sociocultural forces that pervade the lives of pregnant women with SMI, which need to be explored and addressed. Despite advocacy from caregivers, women’s groups, and health professionals, services for mothers with mental illness are unevenly distributed worldwide with majority of the services only available in developed or high-income countries. In low- and middle-income countries (LAMICs), where high rates of maternal morbidity have been reported, the focus is predominantly on physical health with a less emphasis on mental health services. Strategies to overcome this challenge will be needed. In this chapter, we focus on the spectrum of perinatal healthcare for women with SMI.

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References

  • Abel KM, Morgan V (2011) In: Tsuang MT, Tohen M, Jones PB (eds) Mental illness, women, mothers and their children. Textbook in psychiatric epidemiology. Wiley, Chichester, pp 483–507

    Google Scholar 

  • Acera Pozzi R, Yee LM, Brown K, Driscoll KE, Rajan PV (2014) Pregnancy in the severely mentally ill patient as an opportunity for global coordination of care. Am J Obstet Gynecol 210(1):32–37

    PubMed  Google Scholar 

  • Anderson EL, Reti IM (2009) ECT in pregnancy: a review of the literature from 1941 to 2007. Psychosom Med 71(2):235–242

    PubMed  Google Scholar 

  • Austin MP, Highet N, Expert Working Group (2017) Mental health care in the perinatal period: Australian clinical practice guideline. Centre of Perinatal Excellence, Melbourne

    Google Scholar 

  • Baron EC, Hanlon C, Mall S, Honikman S, Breuer E, Kathree T, Luitel NP, Nakku J, Lund C, Medhin G, Patel V, Petersen I, Shrivastava S, Tomlinson M (2016) Maternal mental health in primary care in five low- and middle-income countries: a situational analysis. BMC Health Serv Res 16:53

    PubMed  PubMed Central  Google Scholar 

  • Ben-Sheetrit J, Huller-Harari L, Rasner M, Magen N, Nacasch N, Toren P (2018) Psychiatric disorders and compliance with prenatal care: a 10-year retrospective cohort compared to controls. Eur Psychiatry 49:23–29

    PubMed  Google Scholar 

  • Bergink V, Burgerhout KM, Weigelt K, Pop VJ, de Wit H, Drexhage RC, Kushner SA, Drexhage HA (2013) Immune system dysregulation in first-onset postpartum psychosis. Biol Psychiatry 73(10):1000–1007

    CAS  PubMed  Google Scholar 

  • Bergink V, Burgerhout KM, Koorengevel KM, Kamperman AM, Hoogendijk WJ, Lambregtse-van den Berg MP, Kushner SA (2015) Treatment of psychosis and mania in the postpartum period. Am J Psychiatry 172(2):115–123

    PubMed  Google Scholar 

  • Bergink V, Rasgon N, Wisner KL (2016) Postpartum psychosis: madness, mania, and melancholia in motherhood. Am J Psychiatry 173(12):1179–1188

    PubMed  Google Scholar 

  • Blankley G, Galbally M, Snellen M, Power J, Lewis AJ (2015) Borderline personality disorder in the perinatal period: early infant and maternal outcomes. Australas Psychiatry 23(6):688–692

    PubMed  Google Scholar 

  • Bloomfield J, Rasmussen T (2012) The evolution of trauma-informed practice at the Jean Tweed Centre. In: Poole N, Greaves L (eds) Becoming trauma informed. Centre for Addiction and Mental Health, Toronto

    Google Scholar 

  • Boden R, Lundgren M, Brandt L, Reutfors J, Andersen M, Kieler H (2012) Risks of adverse pregnancy and birth outcomes in women treated or not treated with mood stabilisers for bipolar disorder: population based cohort study. BMJ 345:e7085

    PubMed  PubMed Central  Google Scholar 

  • Boyce P (2017) 50 years of perinatal psychiatry. Aust N Z J Psychiatry 51(9):860–862

    PubMed  Google Scholar 

  • Boyce P, Buist A (2016) Management of bipolar disorder over the perinatal period. Aust Fam Physician 45(12):890–893

    PubMed  Google Scholar 

  • Brockington I (2017) Suicide and filicide in postpartum psychosis. Arch Womens Ment Health 20(1):63–69

    PubMed  Google Scholar 

  • Brockington I, Chandra P, Dubowitz H, Jones D, Moussa S, Nakku J, Quadros Ferre I (2011) WPA guidance on the protection and promotion of mental health in children of persons with severe mental disorders. World Psychiatry 10(2):93–102

    PubMed  PubMed Central  Google Scholar 

  • Chandra PS, Desai G, Reddy D, Thippeswamy H, Saraf G (2015) The establishment of a mother-baby inpatient psychiatry unit in India: adaptation of a Western model to meet local cultural and resource needs. Indian J Psychiatry 57(3):290–294

    PubMed  PubMed Central  Google Scholar 

  • Choi KR, Seng JS (2016) Predisposing and precipitating factors for dissociation during labor in a cohort study of posttraumatic stress disorder and childbearing outcomes. J Midwifery Womens Health 61(1):68–76

    PubMed  PubMed Central  Google Scholar 

  • Christl B, Reilly N, Yin C, Austin MP (2015) Clinical profile and outcomes of women admitted to a psychiatric mother-baby unit. Arch Womens Ment Health 18(6):805–816

    PubMed  Google Scholar 

  • Cox JL, Holden JM, Sagovsky R (1987) Detection of postnatal depression. Development of the 10-item Edinburgh postnatal depression scale. Br J Psychiatry 150:782–786

    CAS  PubMed  Google Scholar 

  • De Genna NM, Feske U, Larkby C, Angiolieri T, Gold MA (2012) Pregnancies, abortions, and births among women with and without borderline personality disorder. Womens Health Issues 22(4):e371–e377

    PubMed  PubMed Central  Google Scholar 

  • Di Prinzio P, Morgan VA, Bjork J, Croft M, Lin A, Jablensky A, McNeil TF (2018) Intellectual disability and psychotic disorders in children: association with maternal severe mental illness and exposure to obstetric complications in a whole-population cohort. Am J Psychiatry 175(12): 1232–1242

    PubMed  Google Scholar 

  • Dolman C, Jones I, Howard LM (2013) Pre-conception to parenting: a systematic review and meta-synthesis of the qualitative literature on motherhood for women with severe mental illness. Arch Womens Ment Health 16(3):173–196

    PubMed  Google Scholar 

  • Dossett EC, Wusirika L, Burt V (2017) No perfect choice. JAMA 318(1):29–30

    PubMed  Google Scholar 

  • Einarson A (2014) Critical evaluation of the literature: understanding the complexities of observational research. In: Galbally M, Lewis AJ, Snellen M (eds) Psychopharmacology and pregnancy: treatment efficacy, risks, and guidelines. Springer, Berlin/Heidelberg, pp 19–31

    Google Scholar 

  • Fisher J (2016) Perinatal psychiatric care needs of women who die by suicide. Lancet Psychiatry 3(3):191–192

    PubMed  Google Scholar 

  • Fisher J, Cabral de Mello M, Patel V, Rahman A, Tran T, Holton S, Holmes W (2012) Prevalence and determinants of common perinatal mental disorders in women in low- and lower-middle-income countries: a systematic review. Bull World Health Organ 90(2):139G–149G

    PubMed  Google Scholar 

  • Forbes F, Wynter K, Wade C, Zeleke BM, Fisher J (2018) Male partner attendance at antenatal care and adherence to antenatal care guidelines: secondary analysis of 2011 Ethiopian demographic and health survey data. BMC Pregnancy Childbirth 18(1):145

    PubMed  PubMed Central  Google Scholar 

  • Frayne J, Nguyen T, Allen S, Rampono J (2009) Motherhood and mental illness-part 2-management and medications. Aust Fam Physician 38(9):688–692

    PubMed  Google Scholar 

  • Frayne J, Brooks J, Nguyen TN, Allen S, Maclean M, Fisher J (2014) Characteristics of men accompanying their partners to a specialist antenatal clinic for women with severe mental illness. Asian J Psychiatr 7(1):46–51

    PubMed  Google Scholar 

  • Frayne J, Nguyen T, Bennett K, Allen S, Hauck Y, Liira H (2017) The effects of gestational use of antidepressants and antipsychotics on neonatal outcomes for women with severe mental illness. Aust N Z J Obstet Gynaecol 57(5):526–532

    PubMed  Google Scholar 

  • Galbally M, Snellen M, Walker S, Permezel M (2010) Management of antipsychotic and mood stabilizer medication in pregnancy: recommendations for antenatal care. Aust N Z J Psychiatry 44(2):99–108

    PubMed  Google Scholar 

  • Galbally M, Snellen M, Lewis AJ (2014) Psychopharmacoloy and pregnancy: treatment efficacy, risks and guidelines. Springer, Berlin/Heidelberg

    Google Scholar 

  • Galbally M, Nguyen TN, Snellen M (2017) Commentary on RANZCP clinical practice guidelines for the management of schizophrenia and related disorders. Aust N Z J Psychiatry 51(3): 289–290

    PubMed  Google Scholar 

  • Galbally M, Frayne J, Watson SJ, Morgan V Snellen M (2019) The association between gestational diabetes mellitus, antipsychotics and severe mental illness in pregnancy: a multicentre study. Aust N Z J Obstet Gynaecol

    Google Scholar 

  • Glangeaud-Freudenthal NM, Sutter-Dallay AL, Thieulin AC, Dagens V, Zimmermann MA, Debourg A, Amzallag C, Cazas O, Cammas R, Klopfert ME, Rainelli C, Tielemans P, Mertens C, Maron M, Nezelof S, Poinso F (2013) Predictors of infant foster care in cases of maternal psychiatric disorders. Soc Psychiatry Psychiatr Epidemiol 48(4):553–561

    PubMed  Google Scholar 

  • Hale TW (2017) Medications and Mothers’ Milk 2017. Springer Publishing Company LLC. New York, NY 10036

    Google Scholar 

  • Hall KS, Steinberg JR, Cwiak CA, Allen RH, Marcus SM (2015) Contraception and mental health: a commentary on the evidence and principles for practice. Am J Obstet Gynecol 212(6):740–746

    PubMed  Google Scholar 

  • Harris EL, Frayne J, Allen S, Renganathan K, Nguyen TN (2018) Psychiatric admission during pregnancy in women with schizophrenia who attended a specialist antenatal clinic. J Psychosom Obstet Gynaecol 40:211–216

    PubMed  Google Scholar 

  • Harrison C, O’callaghan J (2014) A review of pre-birth child protection planning in a tertiary maternity hospital: engaging vulnerable pregnant women. Dev Pract 39:80–86

    Google Scholar 

  • Haskey C, Galbally M (2017) Mood stabilizers in pregnancy and child developmental outcomes: a systematic review. Aust N Z J Psychiatry 51(11):1087–1097

    PubMed  Google Scholar 

  • Hauck Y, Allen S, Ronchi F, Faulkner D, Frayne J, Nguyen T (2013) Pregnancy experiences of Western Australian women attending a specialist childbirth and mental illness antenatal clinic. Health Care Women Int 34(5):380–394

    PubMed  Google Scholar 

  • Hauck Y, Nguyen T, Frayne J, Garefalakis M, Rock D (2015) Sexual and reproductive health trends among women with enduring mental illness: a survey of Western Australian community mental health services. Health Care Women Int 36(4):499–510

    PubMed  Google Scholar 

  • Health, Department of (2018) Clinical practice guidelines: pregnancy care. Government of Australia, Department of Health, Canberra

    Google Scholar 

  • Henshaw C, Cox J, Barton J (2017) Modern management of perinatal psychiatric disorders. RCPsych Publications, London

    Google Scholar 

  • Howard LM, Kumar C, Leese M, Thornicroft G (2002) The general fertility rate in women with psychotic disorders. Am J Psychiatry 159(6):991–997

    PubMed  Google Scholar 

  • Howard L, Hunt K, Slade M, O’Keane V, Senevirante T, Leese M, Thornicroft G, Wiseman M (2008) Camberwell assessment of need for mothers. Royal College of Psychiatrists, London

    Google Scholar 

  • Howard LM, Ryan EG, Trevillion K, Anderson F, Bick D, Bye A, Byford S, O’Connor S, Sands P, Demilew J, Milgrom J, Pickles A (2018) Accuracy of the whooley questions and the Edinburgh postnatal depression scale in identifying depression and other mental disorders in early pregnancy. Br J Psychiatry 212(1):50–56

    PubMed  PubMed Central  Google Scholar 

  • Huybrechts KF, Hernandez-Diaz S, Patorno E, Desai RJ, Mogun H, Dejene SZ, Cohen JM, Panchaud A, Cohen L, Bateman BT (2016) Antipsychotic use in pregnancy and the risk for congenital malformations. JAMA Psychiat 73(9):938–946

    Google Scholar 

  • Jablensky AV, Morgan V, Zubrick SR, Bower C, Yellachich LA (2005) Pregnancy, delivery, and neonatal complications in a population cohort of women with schizophrenia and major affective disorders. Am J Psychiatry 162(1):79–91

    PubMed  Google Scholar 

  • Jones I, Chandra PS, Dazzan P, Howard LM (2014) Bipolar disorder, affective psychosis, and schizophrenia in pregnancy and the post-partum period. Lancet 384(9956):1789–1799

    PubMed  Google Scholar 

  • Judd F, Komiti A, Sheehan P, Newman L, Castle D, Everall I (2014) Adverse obstetric and neonatal outcomes in women with severe mental illness: to what extent can they be prevented? Schizophr Res 157(1–3):305–309

    PubMed  Google Scholar 

  • Judd F, Newman LK, Komiti AA (2018) Time for a new zeitgeist in perinatal mental health. Aust N Z J Psychiatry 52(2):112–116

    PubMed  Google Scholar 

  • Kahneman D (2011) Thinking fast and slow. Farrar Strauss Giroux, New York

    Google Scholar 

  • KEMH (2018) Clinical guidelines: childbirth and mental illness clinic. Obstetrics 131:e140

    Google Scholar 

  • Kendell RE, Chalmers JC, Platz C (1987) Epidemiology of puerperal psychoses. Br J Psychiatry 150:662–673

    CAS  PubMed  Google Scholar 

  • Kendler KS, Ohlsson H, Svikis DS, Sundquist K, Sundquist J (2017) The protective effect of pregnancy on risk for drug abuse: a population, co-relative, co-spouse, and within-individual analysis. Am J Psychiatry 174(10):954–962

    PubMed  PubMed Central  Google Scholar 

  • Kessler ML, Ackerson BJ (2005) Wraparound services: an effective intervention for families impacted by severe mental illness. J Fam Soc Work 8(4):29–45

    Google Scholar 

  • Kimmel MC, Ferguson EH, Zerwas S, Bulik CM, Meltzer-Brody S (2016) Obstetric and gynecologic problems associated with eating disorders. Int J Eat Disord 49(3):260–275

    CAS  PubMed  Google Scholar 

  • Knight M, Bunch K, Tuffnell D, Jayakody H, Shakespeare J, Kotnis R, Kenyon S, Kurinczuk JE, on behalf of MBRRACE-UK (2018) Saving lives, improving mothers’ care – lessons learned to inform maternity care from the UK and Ireland confidential enquiries into maternal deaths and morbidity 2014–16. National Perinatal Epidemiology Unit, Oxford

    Google Scholar 

  • Lewis AJ, Galbally M, Gannon T, Symeonides C (2014) Early life programming as a target for prevention of child and adolescent mental disorders. BMC Med 12:33

    PubMed  PubMed Central  Google Scholar 

  • Lysell H, Dahlin M, Viktorin A, Ljungberg E, D’Onofrio BM, Dickman P, Runeson B (2018) Maternal suicide – register based study of all suicides occurring after delivery in Sweden 1974–2009. PLoS One 13(1):e0190133

    PubMed  PubMed Central  Google Scholar 

  • MacCabe JH, Martinsson L, Lichtenstein P, Nilsson E, Cnattingius S, Murray RM, Hultman CM (2007) Adverse pregnancy outcomes in mothers with affective psychosis. Bipolar Disord 9(3):305–309

    PubMed  Google Scholar 

  • Marvin R, Cooper G, Hoffman K, Powell B (2002) The circle of security project: attachment-based intervention with caregiver-pre-school child dyads. Attach Hum Dev 4(1):107–124

    PubMed  Google Scholar 

  • Massey SH, Wisner KL (2018) Understanding Pregnancy’s protective effect on drug use within a developmental framework. Am J Psychiatry 175(3):286–287

    PubMed  PubMed Central  Google Scholar 

  • McAllister-Williams RH, Baldwin DS, Cantwell R, Easter A, Gilvarry E, Glover V, Green L, Gregoire A, Howard LM, Jones I, Khalifeh H, Lingford-Hughes A, McDonald E, Micali N, Pariante CM, Peters L, Roberts A, Smith NC, Taylor D, Wieck A, Yates LM, Young AH, endorsed by the British Association for Psychopharmacology (2017) British Association for Psychopharmacology consensus guidance on the use of psychotropic medication preconception, in pregnancy and postpartum 2017. J Psychopharmacol 31(5):519–552

    PubMed  Google Scholar 

  • McCullough LB, Coverdale JH, Chervenak FA (2002) Ethical challenges of decision making with pregnant patients who have schizophrenia. Am J Obstet Gynecol 187(3):696–702

    PubMed  Google Scholar 

  • Mehta TM, Van Lieshout RJ (2017) A review of the safety of clozapine during pregnancy and lactation. Arch Womens Ment Health 20(1):1–9

    PubMed  Google Scholar 

  • Miller LJ, Finnerty M (1996) Sexuality, pregnancy, and childrearing among women with schizophrenia-spectrum disorders. Psychiatr Serv 47(5):502–506

    CAS  PubMed  Google Scholar 

  • Mota NP, Chartier M, Ekuma O, Nie Y, Hensel JM, MacWilliam L, McDougall C, Vigod S, Bolton JM (2019) Mental disorders and suicide attempts in the pregnancy and postpartum periods compared with non-pregnancy: a population-based study. Can J Psychiatr 64:482. https://doi.org/10.1177/0706743719838784

    Article  Google Scholar 

  • Muir E, Lojkasek M, Cohen N (1999) Watch, wait, and wonder: a manual describing adyadic infant led approach to problems in infancy and early childhood. The Hincks-Dellcrest Institute, Toronto

    Google Scholar 

  • Munk-Olsen T, Liu X, Viktorin A, Brown HK, Di Florio A, D’Onofrio BM, Gomes T, Howard LM, Khalifeh H, Krohn H, Larsson H, Lichtenstein P, Taylor CL, Van Kamp I, Wesseloo R, Meltzer-Brody S, Vigod SN, Bergink V (2018) Maternal and infant outcomes associated with lithium use in pregnancy: an international collaborative meta-analysis of six cohort studies. Lancet Psychiatry 5(8):644–652

    PubMed  PubMed Central  Google Scholar 

  • Nahar A, Kondapuram N, Desai G, Chandra PS (2017) Catatonia among women with postpartum psychosis in a mother-baby inpatient psychiatry unit. Gen Hosp Psychiatry 45:40–43

    PubMed  Google Scholar 

  • Nguyen TN, Faulkner D, Frayne JS, Allen S, Hauck YL, Rock D, Rampono J (2013) Obstetric and neonatal outcomes of pregnant women with severe mental illness at a specialist antenatal clinic. Med J Aust 199(3 Suppl):S26–S29

    PubMed  Google Scholar 

  • Nguyen T, Brooks J, Frayne J, Watt F, Fisher J (2015) The preconception needs of women with severe mental illness: a consecutive clinical case series. J Psychosom Obstet Gynaecol 36(3):87–93

    PubMed  Google Scholar 

  • Nguyen T, Mordecai J, Watt F, Frayne J (2019) Obstetric and neonatal outcomes of clozapine exposure in pregnancy: a consecutive case series. Arch Womens Ment Health. Jun 15. (Epub ahead of print)

    Google Scholar 

  • NICE (2016) Antenatal and postnatal mental health. National Institute for Health and Care Excellence

    Google Scholar 

  • Oates M (2003) Suicide: the leading cause of maternal death. Br J Psychiatry 183:279–281

    PubMed  Google Scholar 

  • Pare-Miron V, Czuzoj-Shulman N, Oddy L, Spence AR, Abenhaim HA (2016) Effect of borderline personality disorder on obstetrical and neonatal outcomes. Womens Health Issues 26(2): 190–195

    PubMed  Google Scholar 

  • Park JM, Solomon P, Mandell DS (2006) Involvement in the child welfare system among mothers with serious mental illness. Psychiatr Serv 57 (4):493-497

    Google Scholar 

  • Patel V (2007) Mental health in low- and middle-income countries. Br Med Bull 81–82:81–96

    PubMed  Google Scholar 

  • Patel V, Hanlon C (2018) Where there is no psychiatrist: a mental health care manual. Cambridge University Press, Cambridge

    Google Scholar 

  • Patorno E, Huybrechts KF, Bateman BT, Cohen JM, Desai RJ, Mogun H, Cohen LS, Hernandez-Diaz S (2017) Lithium use in pregnancy and the risk of cardiac malformations. N Engl J Med 376(23):2245–2254

    CAS  PubMed  PubMed Central  Google Scholar 

  • Phillips L, Thomas D (2015) The first antenatal appointment: an exploratory study of the experiences of women with a diagnosis of mental illness. Midwifery 31(8):756–764

    PubMed  Google Scholar 

  • Poels EMP, Bijma HH, Galbally M, Bergink V (2018) Lithium during pregnancy and after delivery: a review. Int J Bipolar Disord 6(1):26

    PubMed  PubMed Central  Google Scholar 

  • Rahman A, Fisher J, Bower P, Luchters S, Tran T, Yasamy MT, Saxena S, Waheed W (2013a) Interventions for common perinatal mental disorders in women in low- and middle-income countries: a systematic review and meta-analysis. Bull World Health Organ 91(8):593–601I

    PubMed  PubMed Central  Google Scholar 

  • Rahman A, Surkan PJ, Cayetano CE, Rwagatare P, Dickson KE (2013b) Grand challenges: integrating maternal mental health into maternal and child health programmes. PLoS Med 10(5):e1001442

    PubMed  PubMed Central  Google Scholar 

  • Seeman MV (2012) Intervention to prevent child custody loss in mothers with schizophrenia. Schizophrenia Research and Treatment 1–6

    Google Scholar 

  • Seeman MV (2013) Clinical interventions for women with schizophrenia: pregnancy. Acta Psychiatrica Scandinavica 127(1):12–22

    Google Scholar 

  • Sharma V, Pope CJ (2012) Pregnancy and bipolar disorder: a systematic review. J Clin Psychiatry 73(11):1447–1455

    PubMed  Google Scholar 

  • Snellen M, Thompson G, Murdoch N (2014) The process of obtaining Informed consent when prescribing psychopharmacology in pregnancy. In: Galbally M, Snellen M, Lewis AJ (eds) Psychopharmacology and pregnancy: treatment efficacy, risks, and guidelines. Springer, Heidelberg, pp 5–18

    Google Scholar 

  • Stein A, Pearson RM, Goodman SH, Rapa E, Rahman A, McCallum M, Howard LM, Pariante CM (2014) Effects of perinatal mental disorders on the fetus and child. Lancet 384(9956): 1800–1819

    PubMed  Google Scholar 

  • Stephenson J, Heslehurst N, Hall J, Schoenaker D, Hutchinson J, Cade JE, Poston L, Barrett G, Crozier SR, Barker M, Kumaran K, Yajnik CS, Baird J, Mishra GD (2018) Before the beginning: nutrition and lifestyle in the preconception period and its importance for future health. Lancet 391(10132):1830–1841

    PubMed  PubMed Central  Google Scholar 

  • Thippeswamy H, Dahale A, Desai G, Chandra PS (2015) What is in a name? Causative explanatory models of postpartum psychosis among patients and caregivers in India. Int J Soc Psychiatr 61(8):818–823

    Google Scholar 

  • Thippeswamy H, Desai G, Chandra P (2018) Help-seeking patterns in women with postpartum severe mental illness: a report from southern India. Arch Womens Ment Health 21:573

    PubMed  Google Scholar 

  • Turnell A, Edwards S (1999) Signs of safety: a solution and safety oriented approach to child protection casework. W.W. Norton, New York

    Google Scholar 

  • Ursini G, Punzi G, Chen Q, Marenco S, Robinson JF, Porcelli A, Hamilton EG, Mitjans M, Maddalena G, Begemann M, Seidel J, Yanamori H, Jaffe AE, Berman KF, Egan MF, Straub RE, Colantuoni C, Blasi G, Hashimoto R, Rujescu D, Ehrenreich H, Bertolino A, Weinberger DR (2018) Convergence of placenta biology and genetic risk for schizophrenia. Nat Med 24(6):792–801

    CAS  PubMed  Google Scholar 

  • Vesga-Lopez O, Blanco C, Keyes K, Olfson M, Grant BF, Hasin DS (2008) Psychiatric disorders in pregnant and postpartum women in the United States. Arch Gen Psychiatry 65(7):805–815

    PubMed  PubMed Central  Google Scholar 

  • Viguera AC, Newport DJ, Ritchie J, Stowe Z, Whitfield T, Mogielnicki J, Baldessarini RJ, Zurick A, Cohen LS (2007) Lithium in breast milk and nursing infants: clinical implications. Am J Psychiatry 164(2):342–345

    PubMed  Google Scholar 

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Nguyen, T., Desai, G. (2020). Severe Mental Illness and Reproductive Health. In: Chandra, P., Herrman, H., Fisher, J., Riecher-Rössler, A. (eds) Mental Health and Illness of Women. Mental Health and Illness Worldwide. Springer, Singapore. https://doi.org/10.1007/978-981-10-2369-9_10

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