Abstract
The use of sedation is not new in medicine. In fact, sedation is widely used to alleviate pain and discomfort associated with both invasive procedures such as surgery, as well as severe burns (Claessens et al. 2008; Cherny and Radbruch 2009). Similarly, in Psychiatry it is used in extremely agitated patients, or in those suffering from severe panic attacks. Still, the first descriptions of the use of sedation for symptom-control in advanced stages of incurable diseases were published in 1990–1991, and it was not until 2000 that the term ‘palliative sedation’ (PS) was coined (Claessens et al. 2008). Since then, sedation has been progressively accepted as a therapeutic tool in the care for dying patients (Palliative Medicine) (Claessens et al. 2008; Cherny and Radbruch 2009; Cherny 2006; Krakauer 2009).
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References
Beel, A., S.E. McClement, and M. Harlos. 2002. Palliative sedation therapy: A review of definitions and usages. International Journal of Palliative Nursing 8: 190–199.
Berger, J. 2010. Rethinking guidelines for the use of palliative sedation. Hastings Center Report 40(3): 32–48.
Boyle, J. 2004. Medical ethics and double effect: A case of terminal sedation. Theoretical Medicine and Bioethics 25: 52–60.
Braun, T.C., N.A. Hagen, and T. Clark. 2003. Development of a clinical practice guideline for palliative sedation. Journal of Palliative Medicine 6: 345–350.
Breitbart, W., B. Rosenfeld, H. Pessin, et al. 2000. Depression, hopelessness, and desire for hastened death in terminally ill patients with cancer. JAMA 284: 2907–2911.
Brody, H. 1996. Commentary on Billings and Block’s “Slow Euthanasia”. Journal of Palliative Care 12(4): 38–41.
Broekaert, B. 2000. Palliative sedation defined or why and when terminal sedation is not euthanasia. Journal of Pain and Symptom Management 20(6): S58.
Cassell, E.J., and B.A. Rich. 2010. Intractable end-of-life suffering and the ethics of palliative sedation. Pain Medicine 11: 435–438.
Cherny, N.I. 1998. Commentary: Sedation in response to refractory existential distress: Walking the fine line. Journal of Pain and Symptom Management 16: 404–406.
Cherny, N. 2006. Palliative sedation. In Textbook of palliative medicine, ed. E. Bruera, I. Higginson, C. Ripamonti, and C. von Gunten, 976–987. London: Hodder Arnold.
Cherny, N., and L. Radbruch. 2009. European Association for Palliative Care (EAPC) recommended framework for the use of sedation in palliative care. Palliative Medicine 23(7): 581–593.
Claessens, P., J. Menten, P. Schotsmans, and B. Broeckaert. 2008. Palliative sedation: A review of the research literature. Journal of Pain and Symptom Management 36: 310–333.
Cowan, J.D., and D. Walsh. 2001. Terminal sedation in palliative medicine – Definition and review of the literature. Support Care Cancer 9: 403–407.
de Graeff, A., and M. Dean. 2007. Palliative sedation therapy in the last weeks of life: A literature review and recommendations for standards. Journal of Palliative Medicine 10: 67–85.
Engstrom, J., E. Bruno, B. Holm, and O. Hellzen. 2006. Palliative sedation at end of life – A systematic literature review. European Journal of Oncology Nursing 11: 26–35.
Fainsinger, R., A. Waller, M. Bercovici, et al. 2000. A multicentre international study of sedation for uncontrolled symptoms in terminally ill patients. Palliative Medicine 14: 257–265.
Fundacio Víctor Grífols i Lucas. 2003. Ética y sedación al final de la vida. Cuadernos de la Fundacio Víctor Grífols i Lucas (no 9), Barcelona.
Higgins, P.C., and T. Altilio. 2007. Palliative sedation: An essential place for clinical excellence. Journal of Social Work in End-of-Life & Palliative Care 3: 3–30.
Hospice and Palliative Care Federation of Massachusetts. 2004. Palliative sedation protocol: A report of the Standards and Best Practices Committee. Norwood: Hospice and Palliative Care Federation of Massachusetts.
Jackson, W.C. 2002. Palliative sedation vs. terminal sedation: What’s in a name? The American Journal of Hospice & Palliative Care 19: 81–82.
Jansen, L.A. 2010. Intractable end-of-life suffering and the ethics of palliative sedation: A commentary on Cassell and Rich. Pain Medicine 11: 440–441.
Jansen, L.A., and D.P. Sulmasy. 2002. Sedation, alimentation; hydration, and equivocation: Careful conversation about care at the end of life. Annals of Internal Medicine 136: 845–849.
Krakauer, E.L. 2009. Sedation in palliative medicine. In Oxford textbook of palliative medicine, 4th ed, ed. G. Hanks, N. Cherny, N.A. Christakis, M. Fallon, S. Kaasa, and R.K. Portenoy. Oxford: Oxford University Press.
Levy, M.H., and S.D. Cohen. 2005. Sedation for the relief of refractory symptoms in the imminently dying: A fine intentional line. Seminars in Oncology 32: 237–246.
Morita, T. 2004a. Differences in physician-reported practice in palliative sedation therapy. Support Care Cancer 12: 584–592.
Morita, T. 2004b. Palliative sedation to relieve psycho-existential suffering of terminally ill cancer patients. Journal of Pain and Symptom Management 28: 445–450.
Morita, T., J. Tsunoda, S. Inoue, and S. Chihara. 2000. Terminal sedation for existential distress. The American Journal of Hospice & Palliative Care 17: 189–195.
Morita, T., S. Tsuneto, and Y. Shima. 2002. Definition of sedation for symptom relief: A systematic literature review and a proposal of operational criteria. Journal of Pain and Symptom Management 24: 447–453.
Morita, T., S. Bito, Y. Kurihara, and Y. Uchitomi. 2005. Development of a clinical guideline for palliative sedation therapy using the Delphi method. Journal of Palliative Medicine 8: 716–729.
Mounjt, B. 1996. Morphyn drips, terminal sedation, and slow euthanasia: Definitions and facts, not anecdotes. Journal of Palliative Care 12(4): 31–37.
Moyano, J., S. Zambrano, C. Ceballos, C.M. Santacruz, and C. Guerrero. 2008. Palliative sedation in Latin America: Survey on practices and attitudes. Support Care Cancer 16: 431–435.
Muller-Busch, H.C., I. Andres, and T. Jehser. 2003. Sedation in palliative care – A critical analysis of 7 years experience. BMC Palliative Care 2: 2.
Pomerantz, S.C., H. Bhatt, N.L. Brodsky, D. Lurie, J. Ciesielski, and T.A. Cavalieri. 2004. Physicians’ practices related to the use of terminal sedation: Moral and ethical concerns. Palliative & Supportive Care 2: 15–21.
Porta-Sales, J., J.M. Nuñez-Olarte, R. Altisent-Trota, et al. 2002. Aspectos éticos de la sedación en Cuidados Paliativos: Trabajos del Comité de Ética de la SECPAL. Palliative Medicine (Madrid) 9: 41–46.
Quill, T.E., and I.R. Byock. 2000. Responding to intractable terminal suffering: The role of terminal sedation and voluntary refusal of food and fluids. ACP-ASIM End-of-Life Care Consensus Panel. American College of Physicians-American Society of Internal Medicine. Annals of Internal Medicine 123: 408–414.
Quill, T.E., B. Lo, and D.W. Broca. 1997. Palliative options of last resort: A comparison of voluntary stopping eating and drinking, terminal sedation, physician assisted suicide, and voluntary active euthanasia. JAMA 278: 2099–2104.
Rietjens, J.A., L. van Zuylen, H. van Veluw, L. van der Wijk, A. van der Heide, and C.C. van der Rijt. 2008. Palliative sedation in a specialized unit for acute palliative care in a cancer hospital: Comparing patients dying with and without palliative sedation. Journal of Pain and Symptom Management 36: 228–234.
Rousseau, P. 2005. Existential distress and palliative sedation. Anesthesia and Analgesia 101: 611–612.
Royal Dutch Medical Association Committee on National Guideline for Palliative Sedation. 2009. Guideline for palliative sedation 2009. Utrecht: Royal Dutch Medical Association (KNMG).
Taboada, P. 2006. Principles of bioethics in palliative care. In Textbook of palliative medicine, ed. E. Bruera, I. Higginson, C. Ripamonti, and C. von Gunten, 85–91. London: Hodder Arnold.
Taylor, B.R., and R.M. McCann. 2005. Controlled sedation for physical and existential suffering? Journal of Palliative Medicine 8: 144–147.
Tulsky, J. 2006. Ethics in the practice of palliative care. In Textbook of palliative medicine, ed. E. Bruera, I. Higginson, C. Ripamonti, and C. von Gunten, 92–99. London: Hodder Arnold.
Ventafridda, V., C. Ripamonti, F. De Conno, et al. 1990. Symptom prevalence and control during cancer patient’s last days of life. Journal of Palliative Care 6: 7–11.
Verkerk, M., E. van Wijlick, J. Legemaate, and A. de Graeff. 2007. A national guideline for palliative sedation in the Netherlands. Journal of Pain and Symptom Management 34: 666–670.
Veterans Health Administration National Ethics Committee. 2006. The ethics of palliative sedation as a therapy of last resort. The American Journal of Hospice & Palliative Care 23: 483–491.
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Taboada, P. (2015). Sedation at the End of Life. Clinical Realities, Trends and Current Debate. In: Taboada, P. (eds) Sedation at the End-of-life: An Interdisciplinary Approach. Philosophy and Medicine(), vol 116. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-9106-9_1
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