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Flow-Induced Deformation of a Capsule in Unbounded Stokes Flow

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Visualization and Simulation of Complex Flows in Biomedical Engineering

Part of the book series: Lecture Notes in Computational Vision and Biomechanics ((LNCVB,volume 12))

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Abstract

Dynamics of deformable capsules in fluid flow is great interest in chemical engineering, bioengineering, and food industry. To investigate the motion and deformation of a capsule, both the fluid mechanics of the internal and external liquids and the solid mechanics of the membrane must be solved precisely. To express the elastic behaviours of the solid membrane, two different kinds of modelling are commonly used. One is a continuum constitutive law and the other is a discrete spring network model. This study first examines the correlations between the mechanical properties of the discrete spring network model and those of continuum constitutive laws. We also derive the relationships between the spring constant and continuum properties, such as Young modulus, Poisson ratio, area dilation modulus, and shear elastic modulus. Next, we investigate the motion and deformation of a capsule in simple shear flow. Especially, we analyze the dynamics of a non-spherical capsule in shear. In the absence of inertia effect of fluid motions, a boundary element method is used to compute the internal and external Stokes flow. The results show that the orientation of a non-spherical capsule is variant under time reversal, though that of a rigid particle is invariant. Interestingly, the alignment of a non-spherical capsule over a long time duration shows a transition depending on the shear rate.

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References

  • Abkarian M, Faivre M, Viallat A (2007) Swinging of red blood cells under shear flow. Phys Rev Lett 98:188302

    Article  Google Scholar 

  • Barthès-Biesel D, Walter J, Salsac AV (2010) Computational hydrodynamics of capsules and biological cells. In: C. Pozrikidis (ed) Flow-induced deformation of artificial capsules. Taylor & Francis, Boca Raton

    Google Scholar 

  • Barthès-Biesel D, Yamaguchi T, Ishikawa T, Lac E (2006) From passive motion of capsules to active motion of cells. J Biomech Sci Eng 1:51–68

    Article  Google Scholar 

  • Barthès-Biesel D, Diaz A, Dhenin E (2002) Effect of constitutive laws for two-dimensional membranes on flow-induced capsule deformation. J Fluid Mech 460:211–222

    Article  MATH  Google Scholar 

  • Fischer TM, Stöhr-Liesen M, Schmid-Shönbein H (1978) The red cell as a fluid droplet: tank tread-like motion of the human erythrocyte membrane in shear flow. Science 202:894–896

    Article  Google Scholar 

  • Foessel E, Walter J, Salsac AV, Barthès-Biesel D (2011) Influence of internal viscosity on the large deformation and buckling of a spherical capsule in a simple shear flow. J Fluid Mech 672:477–486

    Google Scholar 

  • Green AE and Adkins JE (1970) Large elastic deformations, 2nd edn. Oxford University Press, Oxford

    Google Scholar 

  • Pozrikidis C (2003) Modeling and simulation of capsules and biological cells. Chapman and Hall/CRC, Boca Raton

    Google Scholar 

  • Pozrikidis C (1992) Boundary integral and singularity methods for linearized viscous flow. Cambridge University Press, Cambridge

    Google Scholar 

  • Omori T, Imai Y, Yamaguchi T, Ishikwa T (2012) Reorientation of a nonspherical capsule in creeping shear flow. Phys Rev Lett 108:138102

    Article  Google Scholar 

  • Omori T, Ishikawa T, Barthès-Biesel D, Salsac AV, Walter J, Imai Y, Yamaguchi T (2011) Comparison between spring network models and continuum constitutive laws: application to the large deformation of a capsule in shear flow. Phys Rev E 83:0419818

    Article  Google Scholar 

  • Skalak R, Tozeren A, Zarda RP, Chien S (1973) Strain energy function of red blood cell membranes. Biophys J 13:245–264

    Article  Google Scholar 

  • Walter J, Salsac AV, Barthès-Biesel D, Tallec PL (2010) Coupling of finite element and boundary integral methods for a capsule in a Stokes flow. Int J Numer Meth Eng 83:829–850

    MATH  Google Scholar 

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Correspondence to Toshihiro Omori .

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Omori, T., Ishikawa, T., Imai, Y., Yamaguchi, T. (2014). Flow-Induced Deformation of a Capsule in Unbounded Stokes Flow. In: Lima, R., Imai, Y., Ishikawa, T., Oliveira, M. (eds) Visualization and Simulation of Complex Flows in Biomedical Engineering. Lecture Notes in Computational Vision and Biomechanics, vol 12. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-7769-9_6

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  • DOI: https://doi.org/10.1007/978-94-007-7769-9_6

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  • Online ISBN: 978-94-007-7769-9

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