Overview
- Contributions from acknowledged leaders in the Field
- Presents methods currently at the forefront, and new emerging approaches
Part of the book series: NATO Science for Peace and Security Series A: Chemistry and Biology (NAPSA)
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Table of contents (31 papers)
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Front Matter
Keywords
About this book
This work presents a snapshot of the state of the art of modern biomolecular crystallography, from crystallisation through structure determination and even interactive presentation on the web. Methods driving the latest automated structure determination pipelines are explained, as well as how to deal with problems such as crystal pathologies that still demand expert analysis. These methods are illustrated through their application to problems of great biological interest, such as the molecular machinery underlying the complement pathway, the mechanism of action of monoamine oxidase inhibitors, and the structure of the eukaryotic ribosome. Complementary approaches, such as neutron diffraction, small angle X-ray scattering, coherent diffraction and computational modelling, are also explored.
Editors and Affiliations
Bibliographic Information
Book Title: Advancing Methods for Biomolecular Crystallography
Editors: Randy Read, Alexandre G. Urzhumtsev, Vladimir Y. Lunin
Series Title: NATO Science for Peace and Security Series A: Chemistry and Biology
DOI: https://doi.org/10.1007/978-94-007-6232-9
Publisher: Springer Dordrecht
eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)
Copyright Information: Springer Science+Business Media Dordrecht 2013
Hardcover ISBN: 978-94-007-6231-2Published: 16 April 2013
Softcover ISBN: 978-94-007-6319-7Published: 16 April 2013
eBook ISBN: 978-94-007-6232-9Published: 03 April 2013
Series ISSN: 1874-6489
Series E-ISSN: 1874-6527
Edition Number: 1
Number of Pages: XIII, 362
Number of Illustrations: 131 b/w illustrations
Topics: Spectroscopy/Spectrometry, Protein Structure, Crystallography and Scattering Methods, Organic Chemistry