Abstract
A change of ventilation (VE), PaCO 2 (arterial CO 2 tension) and PvCO 2 (pulmonary arterial CO 2 tension) with time was not evaluated precisely during exercise or CO 2 rebreathing in humans. In this study, changes of these variables with time were fitted to exponential curves {y = Exp ( x/ T + A ) + k} and compared. When exercise pulmonary hemodynamics was examined in 15 cardiac patients to decide therapies, we asked the patients to undergo CO 2 rebreathing using air with supplementation of consumed O 2 . Arterial and pulmonary blood was drawn every minute. During exercise, T was 28.2 ± 8.4 and 26.8 ± 12.4, and A was 0.80 ± 0.50 and 0.50 ± 0.90 in VE and PvCO 2 , respectively, with no statistical differences. During CO 2 rebreathing, T was 18.6 ± 5.8, 41.8 ± 38.0 and 21.6 ± 9.7 and A was 0.39 ± 0.67, 1.64 ± 1.35 and 0.17 ± 0.83 in VE, PaCO 2 and PvCO 2 , respectively, with statistical difference of PaCO 2 from other variables, suggesting that VE and PvCO 2 showed same mode of change according to time but PaCO 2 did not.
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© 2012 Springer Science+Business Media Dordrecht
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Satoh, T. et al. (2012). Time-Course of Ventilation, Arterial and Pulmonary CO2 Tension During CO2 Increase in Humans. In: Nurse, C., Gonzalez, C., Peers, C., Prabhakar, N. (eds) Arterial Chemoreception. Advances in Experimental Medicine and Biology, vol 758. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-4584-1_9
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DOI: https://doi.org/10.1007/978-94-007-4584-1_9
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