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Cerebellar Sequencing for Cognitive Processing

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Handbook of the Cerebellum and Cerebellar Disorders

Abstract

The idea that cerebellar processing is required in a variety of cognitive functions is well accepted in the neuroscience community. Nevertheless, the definition of the cerebellar role in the different cognitive domains remains obscure. Current data from lesion studies in humans and from experimental lesion in rats on perceptual and cognitive processing are reviewed with special emphasis on cerebellar sequencing properties. Evidence converges in highlighting sequence detection as the key stone of cerebellar functioning across modalities. The hypothesis that sequence detection might represent the main contribution of cerebellar physiology to brain functioning is presented and discussed.

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Author information

Authors and Affiliations

  1. Laboratory of Experimental Neurorehabilitation Unit A – Ataxia Laboratory, I.R.C.C.S. Santa Lucia Foundation, Via Ardeatina 306, Rome, 00179, Italy

    Dr. Marco Molinari

  2. Neurorehabilitation Unit A – Ataxia Laboratory, I.R.C.C.S. Santa Lucia Foundation, Via Ardeatina 306, Rome, 00179, Italy

    Dr. Maria G. Leggio

  3. Department of Psychology, University of Rome La Sapienza, Via dei Marsi 78, Rome, 00185, Italy

    Dr. Maria G. Leggio

Authors
  1. Dr. Marco Molinari
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  2. Dr. Maria G. Leggio
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Corresponding author

Correspondence to Marco Molinari .

Editor information

Editors and Affiliations

  1. Unité d'Etude du Mouvement (UEM), FNRS, Neurologie ULB Erasme, Bruxelles, Belgium

    Mario Manto

  2. Ataxia Unit, Cognitive and Behavioral Neurology Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

    Jeremy D. Schmahmann

  3. Neuroscience Institute of the Cavalieri-Ottolenghi Foundation (NICO), University of Turin, Orbassano, Turin, Italy

    Ferdinando Rossi

  4. Molecular and Integrative Neuroscience Department (MIND), The Scripps Research Institute, California, CA, USA

    Donna L. Gruol

  5. Department of Integrative Physiolgy, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan

    Noriyuki Koibuchi

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Molinari, M., Leggio, M.G. (2013). Cerebellar Sequencing for Cognitive Processing. In: Manto, M., Schmahmann, J.D., Rossi, F., Gruol, D.L., Koibuchi, N. (eds) Handbook of the Cerebellum and Cerebellar Disorders. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-1333-8_76

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