Abstract
This chapter describes the neurodevelopmental and cognitive functioning of infants, children, and adolescents with a congenital heart disease (ConHD). We will discuss the cognitive outcome within three age groups: early development, preschool age and school age, and adolescence. Different cognitive domains such as mental development, intelligence, attention, memory, language, visual perceptual and spatial skills, psychomotor skills, and executive functioning are used to structure the chapter and to keep a clear overview. Infants with ConHD already display lower scores on mental and motor development. In early childhood, gross and fine motor problems and deficits in speech functions and verbal reasoning emerge and to a lesser extent problems with visuospatial skills, number skills, and nonverbal reasoning emerge. As the cognitive demand on children increases, more problems supervene during school period and adolescence on the level of communication, handwriting, attention, visual-spatial functions, and executive functioning. These shortcomings may have a negative impact on the acquisition of adequate reading, writing, and arithmetic skills, placing a burden on the child’s school career. The need for early identification of patients at risk is stressed.
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References
Orton J, Spittle A, Doyle L, Anders P, Boyd R (2009) Do early intervention programs improve cognitive and motor outcomes for preterm infants after discharge? A systematic review. Dev Med Child Neurol 51(11):581–859
Gaynor W, Wernovsky G, Jarvik G, Bernbaum J, Gerdes M, Zackai E, Nord A, Clancy R, Nicolson S, Spray T (2007) Patient characteristics are important determinants of neurodevelopmental outcome at one year of age after neonatal and infant cardiac surgery. J Thorac Cardiovasc Surg 133:1344–1345
McCusker C, Doherty N, Molley B, Casey F, Rooney N, Mulholland C, Sands A, Craig B, Stewart M (2007) Determinants of neuropsychological and behavioural in early childhood survivors of congenital heart disease. Arch Child Dis 92:137–141
Visconti K, Bichell D, Jonas R, Newburger J, Bellinger D (1999) Developmental outcome after surgical versus interventional closure of secundum atrial septal defect in children. Circulation 100(19):145–150
Quartermain M, Ittenbach R, Flynn T, Gaynor J, Zhang X, Licht D, Ichord R, Nance M, Wernovsky G (2010) Neuropsychological status in children after repair of acyanotic congenital heart disease. Pediatrics 126(2):E351–E359
Anderson PJ, De Luca CR, Hutchinson E, Roberts G, Doyle LW, Victorian Infant Collaborative Group (2010) Underestimation of developmental delay by the new Bayley-III Scale. Arch Pediatr Adolesc Med 164(4):352–356
Koseck K (1999) Review and evaluation of the psychometric properties of the revised Bayley Scales of Infant Development. Pediatr Phys Ther 11:198–204
Bellinger D, Rappaport L, Wypij D, Wernovsly G, Newburger J (1997) Patterns of developmental dysfunction after surgery in infancy to correct transposition of the great arteries. J Dev Behav Pediatr 18:75–83
Snookes S, Gunn J, Eldridge J, Donath S, Hunt R, Galea M, Shekerdemian L (2010) A systematic review of motor and cognitive outcomes after early surgery for congenital heart disease. Pediatrics 125:e818–e827
Sananes R, Manlhiot C, Kelly E, Hornberger L, Williams W, MacGregor D, Buncic R, McCrindle B (2012) Neurodevelopmental outcomes after open heart operations before 3 months of age. Ann Thorac Surg 93:1577–1583
Matsuzaki T, Matzui M, Ichica F, Nakazawa J, Hatori A, Yoshikosi A, Miyazaki M, Fujii M, Hagino I, Kagisaki K, Yagihara T (2010) Neurodevelopment in 1-year-old Japanese infants after congenital heart surgery. Pediatr Int 52(3):420–427
Long S, Galea M, Eldridge B, Harris S (2012) Performance of 2-year-old children after early surgery for congenital heart disease on the Bayley Scales of Infant and Toddler Development, Third edition. Early Hum Dev 88:603–607
Sarajuuri A, Lönnqvist T, Mildh L, Rajantie I, Eronen M, Mattila I, Jokinen E (2009) Prospective follow-up study of children with univentricular heart: neurodevelopmental outcome at age 12 months. J Thorac Cardiovasc Surg 137(1):139–145
Sarajuuri A, Jokinen E, Puosi R, Mildh L, Mattila I, Lano A, Lönnqvist T (2010) Neurodevelopment in children with hypoplastic left heart syndrome. J Pediatr 157:414–420
Owen M, Shevell M, Majnemer A, Limperopoulos C (2011) Abnormal brain structure and function in newborns with complex congenital heart defects before open heart surgery: a review of the evidence. J Child Neurol 26:743–755
Donofrio M, duPlessis A, Limperopoulos C (2011) Impact of congenital heart disease on fetal brain development and injury. Curr Opin Pediatr 23:502–511
Bellinger D, Wypij D, Kuban K, Rappaport L, Hickey P, Wernovsky G, Jonas G, Newburger J (1999) Developmental and neurological status of children at 4 years of age after heart surgery with hypothermic circulatory arrest or low-flow cardiopulmonary bypass. Circulation 100:526–532
Creighton D, Robertson C, Suave R, Moddermann D, Alton G, Nettel-Aguire A, Ross D, Rebyka I, The Western Canadian Complex Pediatric Therapies Follow-up Group (2007) Neurocognitive, functional and health outcomes at 5 years of age for children after complex cardiac surgery at 6 weeks or younger. Pediatrics 120(3):e478–e484
Miatton M, De Wolf D, François K, Thiery E, Vingerhoets G (2007) Intellectual, neuropsychological and behavioral functioning in children with tetralogy of fallot. J Thorac Cardiovasc Surg 133:449–455
Majnemer A, Limperopoulos C, Shevell M, Rohlicek C, Rosenblatt B, Tchervenko C (2008) Developmental and functional outcomes at school entry in children with congenital heart defect. J Pediatr 153:55–60
Sarajuuri A, Jokinen E, Mildh L, Tujulin AM, Mattila I, Valanne L, Lönnqvist T (2012) Neurodevelopmental burden at age 5 years in patients with univentricular heart. Pediatrics 130:e1636–e1646
Karsdorp P, Everaerd W, Kindt M, Mulder B (2007) Psychological and cognitive functioning in children and adolescents with congenital heart disease: a meta-analysis. J Ped Psychol 32(5):527–541
Dickinson DF, Sambrooks JE (1979) Intellectual performance in children after circulatory arrest with profound hypothermia in infancy. Arch Dis Child 54:1–6
Bellinger D, Wypij D, duPlessis A, Rappaport L, Jonas R, Wernovsky G, Newburger J (2003) Neurodevelopmental status at eight years in children with dextro-position of the great arteries: the Boston Circulatory Arrest Trial. J Thorac Cardiovasc Surg 126(5):1385–1396
Spijkerboer A, Utens E, Bogers A, Verhulst F, Helbing A (2008) Long-term intellectual functioning and school-related behavioural outcomes in children and adolescents after invasive treatment for congenital heart disease. Br J Devl Psychol 26:457–470
Kern JH, Hinton VJ, Nereo NE, Hayes CJ, Gersony WM (1998) Early developmental outcome after the Norwood procedure for hypoplastic left heart syndrome. Pediatrics 102(5):1148–1152
Sharma R, Choudhary SK, Mohan MR, Padma MV, Jain S, Bhardwaj M, Bha A, Kiran U, Saxena N, Venugopal P (2000) Neurological evaluation and intelligence testing in the child with operated congenital heart disease. Ann Thor Surg 70:575–581
Wray J, Sensky T (1999) Controlled study of preschool development after surgery for congenital heart disease. Arch Dis Child 80:511–516
Haneda K, Itoh T, Togo T, Ohmi M, Mohri H (1996) Effects of cardiac surgery on intellectual function in infants and children. Cardiovasc Surg 4(3):303–307
Hövels-Gürich HH, Seghaye MC, Schnitker R, Wiesne l, Huber W, Minkenberg R, Kotlarek F, Messmer BJ, von Bernuth G (2002) Long-term neurodevelopmental outcomes in school-aged children after neonatal arterial switch operation. J Thorac Cardiovasc Surg 124(3):448–458
Mahle WT, Spray TL, Wernovsk G, Gaynor JW, Clark BJ (2000) Survival after reconstructive surgery for hypoplastic left heart syndrome: a 15-year experience from a single institution. Circulation 102:III 136–III 141
Shillingford A, Glanzmann M, Ittenbach R, Clancy R, Gaynor W, Wernovsky G (2008) Inattention, hyperactivity, and school performance in a population of school-age children with complex congenital heart disease. Pediatrics 121(4):e759–e767
Mlczoch E, Albinni S, Kitzmueller E, Hanslik A, Jalowetz S, Male C, Salzer-Muhar U (2009) Special schooling in children with congenital heart disease: a risk factor for being disadvantaged in the world of employment. Pediatr Cardiol 30:905–910
Oates RK, Simpson JM, Cartmill TB, Turnbull JAB (1995) Intellectual function and age of repair in cyanotic congenital heart disease. Arch Dis Child 72(4):298–301
Hövels –Gürich H, Konrad K, Skorzenski D, Herpertz-Dahlmann B, Messmer B, Seghaye M (2007) Attentional dysfunction in children after corrective cardiac surgery in infancy. Ann Thorac Surg 83(4):1425–1430
Polanczyk G, de Lima M, Horta B (2007) The worldwide prevalence of ADHD: a systematic review and metaregression analysis. Am J Psychiatry 164:942–948
Hansen E, Poole T, Nguyen V, Lerner M, Wigal T, Shannon K, Wigal S, Batra A (2012) Prevalence of ADHD symptoms in patients with congenital heart disease. Pediatr Inter 54:838–843
Mahle W, Wernovsky G (2004) Neurodevelopmental outcomes in hypoplastic left heart syndrome. Pediatr Card Surg Annu Semin Thorac Cardiovasc Surg 7:39–47
Batra A, Alexander M, Silka M (2012) Attention-deficit/hyperactivity disorder, stimulant therapy, and the patient with congenital heart disease: evidence and reason. Pediatr Cardiol 33:394–401
Wright M, Nolan T (1994) Impact of cyanotic heart disease on school performance. Arch Dis Child 71:64–70
Hövels-Gürich HH, Seghaye MC, Sigler M, Kotlarek F, Bartl A, Neuser J, Minkenberg R, Messmer BJ, von Bernuth G (2001) Neurodevelopmental outcome related to cerebral risk factors in children after neonatal arterial switch operation. Ann Thorac Surg 71(3):881–888
Forbess JM, Visconti KJ, Bellinger DC, Howe RJ, Jonas RA (2002) Neurodevelopmental outcomes after biventricular repair of congenital heart defects. J Thorac Cardiovasc Surgery 123(4):631–639
Hövels-Gürich H, Bauer S, Schnitker R, Willmes-von Hinckeldy K, Messmer B, Seghaye MC, Huber W (2008) Long-term outcome of speech and language in children after corrective surgery for cyanotic and acyanotic cardiac defects in infancy. Eur J Ped Neurol 12:378–386
Miatton M, De Wolf D, François K, Thiery E, Vingerhoets G (2007) Neuropsychological performance in school-aged children with a surgically corrected congenital heart disease. J Pediatr 151:73–78
Limperopoulos C, Majnemer A, Shevell MI, Rosenblatt B, Rohlicek C, Tchervenkov C (1999) Neurologic status of newborns with congenital heart defects before open-heart surgery. Pediatrics 103(2):402–408
Hövels-Gürich HH, Seghayge MC, Däbritz S, Messmer BJ, von Bernuth G (1997) Cognitive and motor development in preschool and school-aged children after neonatal arterial switch operation. J Thorac Cardiovasc Surg 114(4):578–585
Limperopoulos C, Majneme A, Shevell MI, Rohlicek C, Rosenblatt B, Tchervenkov C, Darwish HZ (2002) Predictors of developmental disabilities after open-heart surgery in young children with congenital heart defects. J Pediatr 141(5):51–58
Van der Rijken R, Hulstijn W, Hulstijn-Dirkmaat G, Daniëls O, Maasen B (2011) Psychomotor slowness in school-age children with congenital heart disease. Dev Neuropsychol 36(3):388–402
Bellinger D, Bernstein J, Kirkwoord M, Rappaport L, Newburger J (2003) Visual-spatial skills in children after open-heart surgery. J Dev Beh Ped 24(3):169–179
Calderon J, Bonnet D, Courtin C, Concordet S, Plumet MH, Angeard N (2010) Executive function and theory of mind in school-aged children after neonatal corrective cardiac surgery for transposition of the great arteries. Dev Med Child Neurol 52:1139–1144
Bayley N (1993) Manual for the Bayley scales of infant development, 2nd edn. Psychological Corporation, San Antonio
Griffiths R (1986) The abilities of babies. A study in mental measurement. Association for Research in Infant and Child Development, High Wycombe
Piper M, Darrah J (1994) Motor assessment of the developing infant. W.B. Saunders Company, Philadelphia
Beery K (1997) The Beery-Buktenica developmental test of visual-motor integration, 4th edn. Modern Curriculum Press, Parsipanny
Connors C (1995) Connor’s continuous performance test. Multi-Health Systems, Inc, New York
Dunn L, Dunn L (1981) The peabody picture vocabulary test-revised. American Guidances Service, Circles Pines
Henderson S, Sudgen D (1992) Movement assessment battery for children manual. The Psychological Corporation, London
Korkman M, Kirk U, Kemps S (1998) NEPSY: a developmental neuropsychological assessment manual. Psychological Corporation, San Antonio
Wechsler D (2002) Wechsler preschool and primary scale of intelligence, Revised 3rd edn. Psychological Corporation, San Antonio
Heaton R, Chelune G, Talley J, Kay G, Curtiss G (1993) Wisconsin card sorting test manual. Revised and expanded. Psychological Assessment Resources, Odessa
Reitan R, Davidson L (1974) Clinical neuropsychology: current status and applications. Hemispher, New York
Rey A (1941) L’examen psychologique dans le cas d’encephalopathie traumatique [Psychological examination of traumatic encephalopathy]. Arch Psychol 28:286–340
Schmidt M (1996) Rey auditory and verbal learning test. A handbook. Western Psychological Services, Los Angeles
Shallice T (1982) Specific impairments of planning. Philos Trans R Soc Lond 298:199–209
Wechsler D (1991) Wechsler intelligence scale for children, 3rd edn. The Psychological Corporation, San Antonio
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Miatton, M. (2015). Neuropsychological Aspects in Children and Adolescents with ConHD. In: Callus, E., Quadri, E. (eds) Clinical Psychology and Congenital Heart Disease. Springer, Milano. https://doi.org/10.1007/978-88-470-5699-2_5
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DOI: https://doi.org/10.1007/978-88-470-5699-2_5
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