Abstract
Articular manifestations are frequent in BD since articulations are involved in 40–74 % of BD patients. Joint involvement is the first manifestation of BD in 11–34 % and may appear several years before other symptoms. Knees, wrists, ankles, and elbows are more often affected while the involvement of the small joints of hands and feet is less common. Arthralgia is the main symptoms in 80 % of patients while arthritis is less common and includes mono-articular and oligo-articular lesions. Erosive changes are rare. The analysis of BD synovitis frequently shows a neutrophilic inflammation. Muscle involvement is uncommon in BD and it mainly affects the lower extremities. Authors have described neutrophil-mediated vasculitis and myositis in BD. Moreover, muscle manifestations can be induced by BD treatment such as myopathy and rhabdomyolysis induced by colchicine.
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Desbois, AC., Wechsler, B., Saadoun, D. (2014). Articular and Muscular Manifestations in Behçet’s Disease. In: Emmi, L. (eds) Behçet's Syndrome. Rare Diseases of the Immune System. Springer, Milano. https://doi.org/10.1007/978-88-470-5477-6_10
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DOI: https://doi.org/10.1007/978-88-470-5477-6_10
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