Abstract
Selenium (Se) and tellurium (Te) are chalcogen elements belonging to group 16 in the periodic table. These elements have unique physical, chemical, and biological properties. Se and Te form Se- or Te-containing compounds having Se- or Te-carbon covalent bond(s), i.e., selenometabolites or tellurometabolites, respectively, in their metabolic pathways. In this chapter, the speciation and identification of selenometabolites and tellurometabolites in animal and plant samples are highlighted. First, the instruments required for analyses are overviewed. In particular, hyphenated techniques consisting of high-performance liquid chromatography and inductively coupled plasma mass spectrometry or electrospray ionization (tandem) mass spectrometry are focused on. Then, newly identified metabolites are introduced. The identification of selenosugars in urine, selenohomolanthionine in Se-accumulating plants, selenoneine in marine animals, trimethyltelluronium ion in urine, Te-methyltellurocysteine in Se-accumulating plants, and selenocyanate in cultured cells is discussed.
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Acknowledgments
This study was supported by JSPS KAKENHI Grant Numbers 24659022, 26293030, 15K14991, and 16H05812, and a grant from the Food Safety Commission, Cabinet Office, Government of Japan (Research Program for Risk Assessment Study on Food Safety, No 1601).
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Ogra, Y. (2017). Speciation and Identification of Chalcogen-Containing Metabolites. In: Ogra, Y., Hirata, T. (eds) Metallomics. Springer, Tokyo. https://doi.org/10.1007/978-4-431-56463-8_2
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