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The Efficacies and Issues for Endoscopic Assessment of Mucosal Healing in Patients with Crohn’s Disease

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Advances in Endoscopy in Inflammatory Bowel Disease

Abstract

Mucosal healing has been a focus of attention as an emerging ideal treatment goal of Crohn’s disease. Endoscopy is the gold standard for evaluating mucosal lesion. Objective precise monitoring, especially for the small bowel, is important for stratifying the treatment strategy. Some limitations and issues for definition of mucosal healing, accessibility of stricture or adhesion, feasible endoscopic score still remain. It is important in clinical practice to identify the appropriate time for intensifying the CD treatment for small ulcerative lesion endoscopically. There are characters for each imaging modality, for instance assessment of intestinal tract wall and extrawall information. The combination with other complementary imaging modalities or biomarkers is useful in optimizing the CD treatment strategy. An appropriate accelerated step-up treatment strategy combined with stratified precise monitoring of the SB should provide optimal prognosis in patients with CD. Endoscopic prediction of long-term prognosis or efficacy of treatment is an important subject for investigation.

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Correspondence to Kenji Watanabe .

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Watanabe, K. et al. (2018). The Efficacies and Issues for Endoscopic Assessment of Mucosal Healing in Patients with Crohn’s Disease. In: Hibi, T., Hisamatsu, T., Kobayashi, T. (eds) Advances in Endoscopy in Inflammatory Bowel Disease. Springer, Tokyo. https://doi.org/10.1007/978-4-431-56018-0_19

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  • DOI: https://doi.org/10.1007/978-4-431-56018-0_19

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