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High-Resolution Computed Tomography of Honeycombing and IPF/UIP

To What Extent Can Honeycomb Lung Be Diagnosed by Imaging? To What Extent Can IPF Diagnosis Be Made by HRCT?

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Idiopathic Pulmonary Fibrosis

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Abstract

Typical and atypical imaging findings, differential diagnosis, complications of disease itself and roles of imaging, and problems in diagnosis of idiopathic pulmonary fibrosis/usual interstitial pneumonia (IPF/UIP) are described. Pathologic hallmarks of IPF/UIP are perilobular/periacinar fibrosis, temporal/spatial heterogeneity, advanced fibrosis, and small concentrated areas of nearly normal lung. Typical high-resolution computed tomographic (HRCT) features of IPF/UIP are subpleurally located reticular opacity or honeycomb lung in the dorsal aspect of bilateral lower lobes. Honeycomb lung (honeycombing) is a key finding in the diagnosis of IPF/UIP, but experienced radiologists sometimes disagree in judging honeycomb lung at HRCT. Early diagnosis of IPF/UIP requires establishment of diagnostic criteria other than honeycombing and investigation of HRCT findings that correspond with temporal and spatial heterogeneity.

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  1. Department of Diagnostic Radiology, Saitama International Medical Center, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama, 350-1298, Japan

    Fumikazu Sakai

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  1. Department of Respiratory Medicine, Tokyo Medical University, Ibaraki Medical Center , Ibaraki, Japan

    Hiroyuki Nakamura

  2. Department of Respiratory Medicine , Tokyo Medical University, Ibaraki Medical Center, Ibaraki, Japan

    Kazutetsu Aoshiba

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Sakai, F. (2016). High-Resolution Computed Tomography of Honeycombing and IPF/UIP. In: Nakamura, H., Aoshiba, K. (eds) Idiopathic Pulmonary Fibrosis. Springer, Tokyo. https://doi.org/10.1007/978-4-431-55582-7_6

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  • Online ISBN: 978-4-431-55582-7

  • eBook Packages: MedicineMedicine (R0)

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