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Innovations in Measuring Cellular Mechanics

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Vascular Engineering

Abstract

This article describes several novel mechanical methods for elucidating cellular responses to different types of mechanical loading (adhesive, pulling, pushing, shearing, and stretching forces). Understanding how cells deform and transmit stresses into the cell is important for gene expression, cytoskeletal remodeling, and focal adhesion reorganization and crucial for a variety of higher fundamental cell functions including cell division, motility, and differentiation. Introducing these unique methods of measuring and understanding cellular mechanics, therefore, provides a valuable platform for cell biology research.

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Acknowledgments

We thank Dr. Ben Fabry for helpful discussions and Dr. Vicky Jackiw for proofreading the manuscript. This work was supported in part by grants from Deutscher Akademischer Austauschdienst (DAAD) and Deutsche Forschungsgemeinschaft (DFG).

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Authors and Affiliations

  1. Department of Physics, Biophysics Group, University of Erlangen-Nuremberg/Friedrich-Alexander-University (FAU), Henkestr. 91, 91052, Erlangen, Germany

    Navid Bonakdar, Achim Schilling, Richard Gerum & Wolfgang H. Goldmann

  2. Department of Medicine, Mass. General Hospital/Harvard Medical School, Building 149, 13th Street, Charlestown, MA, 02129, USA

    José Luis Alonso

Authors
  1. Navid Bonakdar
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  2. Achim Schilling
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  3. Richard Gerum
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  4. José Luis Alonso
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  5. Wolfgang H. Goldmann
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Corresponding author

Correspondence to Wolfgang H. Goldmann .

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Editors and Affiliations

  1. Waseda University, Tokyo, Tokyo, Japan

    Kazuo Tanishita

  2. The University of Tokyo, Tokyo, Tokyo, Japan

    Kimiko Yamamoto

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Bonakdar, N., Schilling, A., Gerum, R., Alonso, J.L., Goldmann, W.H. (2016). Innovations in Measuring Cellular Mechanics. In: Tanishita, K., Yamamoto, K. (eds) Vascular Engineering. Springer, Tokyo. https://doi.org/10.1007/978-4-431-54801-0_14

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  • DOI: https://doi.org/10.1007/978-4-431-54801-0_14

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