Abstract
The application of collagen matrices in covering wound defects has been under investigation for quite some time. First applications led to the development of Integra®, a well-known product consisting of collagen and chondroitin sulfate cross-linked with glutaraldehyde and contained on a silicon foil. Application of this product requires a two-stage procedure necessitating hospitalisation of the recipient for about 2 weeks. Subsequent to vascularisation of the collagen, the foil is removed and the collagen surface is covered with autologous split skin in the second stage. The long hospitalisation period creates a need for a material of improved angiogenic capabilities.
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© 2013 Springer-Verlag Wien
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Pallua, N., Markowicz, M., Grieb, G., Steffens, G. (2013). Collagen Matrices with Enhanced Angiogenic and Regenerative Capabilities. In: Kamolz, LP., Lumenta, D. (eds) Dermal Replacements in General, Burn, and Plastic Surgery. Springer, Vienna. https://doi.org/10.1007/978-3-7091-1586-2_7
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DOI: https://doi.org/10.1007/978-3-7091-1586-2_7
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