Abstract
Although invasive mechanical ventilation (IMV) is an effective technique for supporting alveolar ventilation, it has many associated complications. In intensive care unit (ICU) patients, nosocomial infections are major causes of mortality and morbitidy. The use of invasive devices such as the endotracheal tube is the most important factor for producing nosocomial infections [1]. Ventilator-associated pneumonia (VAP)—defined as the development of parenchymal lung infection after at least 48 h of IMV—is the most common nosocomial infection in the ICU. It is associated with prolonged hospitalization, increased health care costs, and mortality. The incidence of VAP ranges from 6 to 52 %. The risk increases at a rate of 1–3 % for each day that a patient is on IMV. The main pathogenic mechanism for the development of VAP is aspiration of colonized oropharyngeal secretions at the time of intubation or throughout the period on IMV. The risk factors for VAP are shown in Table 31.1.
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References
Baudry T, Ader F. Non-invasive mechanical ventilation to prevent ICU-acquired infection. Infect Disord Dryg Targets. 2011;11:384–8.
Girou E, Brun-Buisson C, Taille S, et al. Secular trends in nosocomial infections and mortality associated with noninvasive ventilation in patients with exacerbation of COPD and pulmonary edema. JAMA. 2003;290:2985–91.
Hess DR. Noninvasive positive-pressure ventilation and ventilator-associated pneumonia. Respir Care. 2005;50:924–9.
Ferrer M, Esquinas A, Arancibia F, et al. Noninvasive ventilation during persistent weaning failure: a randomized controlled trial. Am J Respir Crit Care Med. 2003;168:70–6.
Nava S, Ambrosino N, Clini E, et al. Noninvasive mechanical ventilation in the weaning of patients with respiratory failure due to chronic obstructive pulmonary disease. A randomized, controlled trial. Ann Intern Med. 1998;128:721–8.
Chen J, Qui D, Tao D. Time for extubation and sequential noninvasive mechanical ventilation in COPD patients with exacerbated respiratory failure who received invasive ventilation. Zhonghua Jie He He Hu Xi Za Zhi. 2001;24:99–100.
Ciledag A, Kaya A, Akdogan BB, et al. Early use of noninvasive mechanical ventilation in patients with acute hypercapnic respiratory failure in a respiratory ward: a prospective study. Arch Bronconeumol. 2010;46:538–42.
Wood KA, Lewis L, Von Harz B, et al. The use of noninvasive positive pressure ventilationi in emergency department. Chest. 1998;113:1339–46.
Poponick JM, Renston JP, Bennett RP, et al. Use of a ventilatory support system (BIPAP) for acute respiratory failure in the emergency department. Chest. 1999;116:166–71.
Plant PK, Owen JL, Eliot MW. A multicentre randomised controlled trial of the early use of non-invasive ventilation in acute exacerbation of chronic obstructive pulmonary disease on general respiratory wards. Lancet. 2000;335:1931–5.
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Çiledağ, A., Kaya, A. (2014). Noninvasive Mechanical Ventilation to Prevent Intensive Care Unit-Acquired Infection. In: Esquinas, A. (eds) Noninvasive Ventilation in High-Risk Infections and Mass Casualty Events. Springer, Vienna. https://doi.org/10.1007/978-3-7091-1496-4_31
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DOI: https://doi.org/10.1007/978-3-7091-1496-4_31
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