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Endocrine Diseases

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Braun-Falco´s Dermatology

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Abstract

Diseases of endocrine organs and altered secretion of hormones are often associated with characteristic skin lesions. The skin’s ability to react to changes in hormone levels depends on the expression of specific receptors, which fluctuates considerably depending on the skin area. Otherwise, additional factors such as blood circulation, trauma, UV exposure, and the microbiome play an important role. The skin can be the site of pathological changes that occur primarily in an endocrine organ. This is the case with autoimmune diseases, where humoral or cellular immune responses can be directed against both an endocrine organ and the skin. Examples are vitiligo in Addison’s disease or autoimmune thyroiditis. Hormone-secreting tumors of other organs can also be associated with typical skin changes. In addition, the skin is able to produce various hormones such as prolactin, thyroid-stimulating hormone (TSH), thyrotropic hormone (TRH), corticotropin-releasing hormone (CRH), melatonin, melanocyte-stimulating hormones (α-, β-, γ-MSH), adrenocorticotropin (ACTH), and endogenous opioids.

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Author information

Authors and Affiliations

  1. Clinic for Dermatology, University Hospital Münster, Münster, Germany

    Thomas Luger & Markus Böhm

Authors
  1. Thomas Luger
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  2. Markus Böhm
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Corresponding author

Correspondence to Thomas Luger .

Editor information

Editors and Affiliations

  1. Department of Dermatology, Venerology and Allergology, University of Munich, Munich, Germany

    Gerd Plewig

  2. Department of Dermatology, Venerology and Allergology, University of Munich, Munich, Germany

    Lars French

  3. Department of Dermatology, Venerology and Allergology, University of Munich, Munich, Germany

    Thomas Ruzicka

  4. Department of Dermatology, Venerology and Allergology, University of Frankfurt, Frankfurt, Germany

    Roland Kaufmann

  5. Department of Dermatology and Allergology, University of Marburg, Marburg, Germany

    Michael Hertl

Section Editor information

  1. Head of the Department of Dermatology, Venerology and Allergology, Frankfurt University Hospital, Frankfurt am Main, Germany

    Roland Kaufmann

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Luger, T., Böhm, M. (2022). Endocrine Diseases. In: Plewig, G., French, L., Ruzicka, T., Kaufmann, R., Hertl, M. (eds) Braun-Falco´s Dermatology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-63709-8_98

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  • DOI: https://doi.org/10.1007/978-3-662-63709-8_98

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  • Print ISBN: 978-3-662-63708-1

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