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Histiocytoses

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Braun-Falco´s Dermatology

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Abstract

Histiocytoses are caused by an accumulation of dendritic cells or macrophages. Five groups are distinguished: the Langerhans cell group, cutaneous and mucocutaneous non-Langerhans cell histiocytoses, malignant histiocytoses, Rosai-Dorfman disease, and hemophagocytic lymphohistiocytosis. The rare Langerhans cell histiocytoses include localized to generalized as well as self-limiting to life-threatening manifestations in children and adults. The bones and skin are most frequently affected. The more frequent, usually benign non-Langerhans cell histiocytoses are based on nodular to diffuse macrophage-dominated dermatitis. The xanthogranuloma family mainly affects children, and spontaneous remission usually occurs. Further histiocytoses are very rare. Malignant histiocytosis or hemophagocytic lymphohistiocytosis can be life threatening.

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Authors and Affiliations

  1. University Clinic of Dermatology, Venereology and Allergology, Innsbruck, Austria

    Gudrun Ratzinger & Bernhard Zelger

Authors
  1. Gudrun Ratzinger
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  2. Bernhard Zelger
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Correspondence to Gudrun Ratzinger .

Editor information

Editors and Affiliations

  1. Department of Dermatology, Venerology and Allergology, University of Munich, Munich, Germany

    Gerd Plewig

  2. Department of Dermatology, Venerology and Allergology, University of Munich, Munich, Germany

    Lars French

  3. Department of Dermatology, Venerology and Allergology, University of Munich, Munich, Germany

    Thomas Ruzicka

  4. Department of Dermatology, Venerology and Allergology, University of Frankfurt, Frankfurt, Germany

    Roland Kaufmann

  5. Department of Dermatology and Allergology, University of Marburg, Marburg, Germany

    Michael Hertl

Section Editor information

  1. Head of the Department of Dermatology, Venerology and Allergology, Frankfurt University Hospital, Frankfurt am Main, Germany

    Roland Kaufmann

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Ratzinger, G., Zelger, B. (2022). Histiocytoses. In: Plewig, G., French, L., Ruzicka, T., Kaufmann, R., Hertl, M. (eds) Braun-Falco´s Dermatology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-63709-8_112

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  • DOI: https://doi.org/10.1007/978-3-662-63709-8_112

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