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Neuroendokrine Neoplasien der Bronchien

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Endokrine Chirurgie

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Zusammenfassung

Neuroendokrine Lungentumoren treten insgesamt selten auf. Diese Gruppe umfasst vier Tumorarten: die typischen (TC) und atypischen (AC) Karzinoidtumoren, die großzelligen neuroendokrinen Karzinome (LCNC) sowie die kleinzelligen Karzinome (SCNC). Die Tumoren unterscheiden sich histologisch in ihrer Mitoserate und dem Auftreten von Nekrosen. Es empfiehlt sich, nach Abschluss der Staginguntersuchungen die Befunde in einem interdisziplinären Tumorboard zu besprechen und eine Therapieempfehlung zu erarbeiten. Bei den TC und AC steht die Operation im Vordergrund. Wenn möglich, wird eine anatomische Resektion mit einer radikalen mediastinalen Lymphadenektomie durchgeführt. Bei den LCNC und SCNC liegt meist schon ein fortgeschrittenes Stadium vor, sodass sich nur in ausgewählten Fällen eine Operation empfiehlt. In den überwiegenden Fällen wird eine Chemotherapie ggf. in Kombination mit einer Bestrahlung durchgeführt. Die Langzeitprognose hängt von der Tumoraggressivität ab und ist bei den typischen Karzinoidtumoren am besten und bei den kleinzelligen Karzinomen am schlechtesten.

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Authors and Affiliations

  1. Klinik für Viszeral-, Thorax- und Gefäßchirurgie, Universitätsklinikum Gießen und Marburg GmbH, Marburg, Deutschland

    Andreas Kirschbaum

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  1. Andreas Kirschbaum
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Correspondence to Andreas Kirschbaum .

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Editors and Affiliations

  1. Klinik für Visceral-, Thorax- und Gefäßchirurgie, Universitästklinikum Gießen und Marburg GmbH, Marburg, Deutschland

    Detlef K. Bartsch

  2. Klinik für Visceral-, Thorax- und Gefäßchirurgie, Universitästklinikum Gießen und Marburg GmbH, Marburg, Deutschland

    Katharina Holzer

Section Editor information

  1. Klinik für Visceral-, Thorax- und Gefäßchirurgie, Philipps-Universität Marburg, Marburg, Deutschland

    Detlef K. Bartsch

  2. Klinik für Visceral-, Thorax- und Gefäßchirurgie, Philipps-Universität Marburg, Marburg, Deutschland

    Katharina Holzer

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© 2023 Der/die Autor(en), exklusiv lizenziert an Springer-Verlag GmbH, DE, ein Teil von Springer Nature

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Kirschbaum, A. (2023). Neuroendokrine Neoplasien der Bronchien. In: Bartsch, D.K., Holzer, K. (eds) Endokrine Chirurgie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-63317-5_49

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  • DOI: https://doi.org/10.1007/978-3-662-63317-5_49

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