Zusammenfassung
Das Kapitel geht auf die Symptome Dyspnoe und Husten ein und behandelt in einem Unterkapitel das Thema Pleuraerguss.
Dyspnoe ist ein häufiges Symptom bei Kindern mit und ohne onkologische Grunderkrankung. Bei 50–60 % der Kinder mit Krebserkrankungen tritt Dyspnoe in den letzten vier Lebenswochen auf und wird retrospektiv durch die Eltern in 60–80 % der Fälle als leidvoll beschrieben. In der pädiatrischen Palliativversorgung spielt Dyspnoe insbesondere für Patienten mit zystischer Fibrose (CF), Muskelatrophien oder restriktiven Lungenerkrankungen (z. B. bei ausgeprägter Skoliose bei schwerer Mehrfachbehinderung) eine große Rolle. Ein ebenfalls häufiges und belastendes, aber bisher in der Literatur nur wenig beachtetes Symptom in der Palliativsituation, ist Husten. Husten ist körperlich sehr erschöpfend, kann Symptome wie Dyspnoe und Schmerzen verstärken und z. B. zu Appetitlosigkeit, Schlaflosigkeit, Erbrechen u. a. m. führen. Das Kapitel gibt in vielen Tabellen und Übersichten Hinweise zur Differenzialdiagnostik, medikamentösen Therapie sowie wertvolle Tipps aus der Pflege.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
Literatur
Alonso JC (2010) Pleural effusion in liver disease. Semin Respir Crit Care Med 31(06):698–705
Anbar RD (2001) Self-hypnosis for the treatment of functional abdominal pain. Clin Pediatr (Phila) 40(8):447–451
Anbar RD, Linden JH (2010) Understanding dissociation and insight in the treatment of shortness of breath with hypnosis: a case study. Am J Clin Hypn 52(4):263–273
Bach JR, Ishikawa Y, Kim H (1997) Prevention of pulmonary morbidity for patients with duchenne muscular dystrophy. Chest 112(4):1024–1028
Baig MA, Majeed MB, Attar BM et al (2018) Efficacy and safety of indwelling pleural catheters in management of hepatic hydrothorax: a systematic review of literature. Cureus 10(8):e3110
Banderali G, Riva E, Fiocchi A et al (1995) Efficacy and tolerability of levodropropizine and dropropizine in children with non-productive cough. J Int Med Res 23(3):175–183
Barnes H, McDonald J, Smallwood N et al (2016) Opioids for the palliation of refractory breathlessness in adults with advanced disease and terminal illness. Cochrane database of systematic reviews(3):CD011008.pub2
Bausewein C, Booth S, Gysels M et al (2008) Non-pharmacological interventions for breathlessness in advanced stages of malignant and non-malignant diseases Cochrane Database Syst Rev 2
Ben-Aharon I, Gafter-Gvili A, Paul M et al (2008) Interventions for alleviating cancer-related dyspnea: A systematic review. J Clin Oncol 26(14):2396–2404
Bramley K, DeBiasi E, Puchalski J (2018) Indwelling pleural catheter placement for nonmalignant pleural effusions. Semin Respir Crit Care Med 39(06):713–719
Bundesärztekammer, Bundesvereinigung K, Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen F (2018) Nationale Versorgungs-Leitlinie Asthma – Leitlinienreport. BÄK; KBV; AWMF, 3, www.asthma.versorgungsleitlinien.de, Letzter Zugriff am 28.02.2020
Campbell ML, Templin T, Walch J (2010) A respiratory distress observation scale for patients unable to self-report dyspnea. J Palliat Med 13(3):285–290
Campbell ML, Templin TN (2015) Intensity cutpoints for the respiratory distress observation scale. Palliat Med 29(5):436–442
Cashen K, Petersen TL (2017) Pleural Effusions and Pneumothoraces. Pediatr Rev 38(4):170–181
Chalhoub M, Harris K, Castellano M et al (2011) The use of the PleurX catheter in the management of non-malignant pleural effusions. Chron Respir Dis 8(3):185–191
Dahlheim M, Schwartz T, Bánffy-Jósika E (2010) Nichtinterventionelle Multicenterstudie zur Therapie des unproduktiven Reizhustens mit Noscapin im Vergleich zu Codein/Dihydrocodein. Atemwegs- und Lungenkrankheiten 36:35–40
Dellon EP, Shores MD, Nelson KI et al (2010) Family caregiver perspectives on symptoms and treatments for patients dying from complications of cystic fibrosis. J Pain Symptom Manag 40(6):829–837
den Hollander BS, Connolly BL, Sung L et al (2014) Successful use of indwelling tunneled catheters for the management of effusions in children with advanced cancer. Pediatr Blood Cancer 61(6):1007–1012
Dulin JD, Coyne PJ (2020) Nebulized vasopressin for the control of hematemesis and hemoptysis in a child with recurrent, refractory stage III burkitt lymphoma. J Palliat Care 35(2):71–74
Duval M, Wood C (2002) Traitement des symptômes non douloureux chez l’enfant en fin de vie. Arch Pediatr 9(11):1173–1178
Flume PA, Yankaskas JR, Ebeling M et al (2005) Massive hemoptysis in cystic fibrosis*. Chest 128(2):729–738
Frank W (2004) Diagnostisches vorgehen beim pleuraerguss current diagnostic approach to pleural effusion. Pneumologie 58(11):777–790
Galbraith S, Fagan P, Perkins P et al (2010) Does the use of a handheld fan improve chronic dyspnea? A randomized, controlled, crossover trial. J Pain Symptom Manag 39(5):831–838
Garske D, Schmidt P, Hasan C et al (2016) Palliativversorgung auf der pädiatrischen Palliativstation „Lichtblicke“ – Eine retrospektive Studie. Z Palliativmed 17(6):302–307
Hagen N, Temple WJ, Baker T (1994) Cough as a systemic manifestation of cancer. J Pain Symptom Manag 9(1):3–4
Hankerson MJ, Raffetto B, Mallon WK et al (2015) Nebulized tranexamic acid as a noninvasive therapy for cancer-related hemoptysis. J Palliat Med 18(12):1060–1062
Hoffer FA, Hancock ML, Hinds PS et al (2007) Pleurodesis for effusions in pediatric oncology patients at end of life. Pediatr Radiol 37(3):269–273
Jassal SS, Brook L, Aindow A (2020) The Association of Paediatric Palliative Medicine – Master Formulary (APPM, 5th edition). https://www.appm.org.uk/guidelines-resources/appm-master-formulary/, letzter Zugriff am 28.02.2020
Jean-Baptiste E (2000) Clinical assessment and management of massive hemoptysis. Crit Care Med 28(5):1642–1647
Komura S, Rodriguez RM, Peabody CR (2018) Hemoptysis? Try inhaled tranexamic acid. J Emerg Med 54(5):e97–ee9
Light RW (2010) Pleural effusion in pulmonary embolism. Semin Respir Crit Care Med 31(06):716–722
McCracken DJ, Porcel JM, Rahman NM (2018) Malignant pleural effusions: management options. Semin Respir Crit Care Med 39(06):704–712
McGraw MD, Galambos C, Stillwell PC (2017) Uremic pleuritis: A case report and review of recurrent exudative pleural effusions in children. Pediatr Pulmonol 52(9):E52–EE4
Molassiotis A, Bailey C, Caress A et al (2010) Interventions for cough in cancer. Cochrane Database Syst Rev Rev 9:CD007881
Morice AH, Menon MS, Mulrennan SA et al (2007) Opiate therapy in chronic cough. Am J Respir Crit Care Med 175(4):312–315
Moroni M, Porta C, Gualtieri G et al (1996) Inhaled sodium cromoglycate to treat cough in advanced lung cancer patients. Br J Cancer 74(2):309–311
Naum R, Speed B (2019) Hemoptysis in pediatric patients. Cureus 11(3):e4305
Nolte-Buchholtz S, Zernikow B, Wager J (2018) Pediatric patients receiving specialized palliative home care according to german law: a prospective multicenter cohort study. Children (Basel, Switzerland) 5(6):E66
Oduwole O, Udoh EE, Oyo-Ita A et al (2018) Honey for acute cough in children. Cochrane Database Syst Rev 4:(CD007094)
Patil M, Dhillon SS, Attwood K et al (2017) Management of benign pleural effusions using indwelling pleural catheters: a systematic review and meta-analysis. Chest 151(3):626–635
Pieper L, Wager J, Zernikow B (2018) Intranasal fentanyl for respiratory distress in children and adolescents with life-limiting conditions. BMC Palliat Care 17(1):106
Porcel JM (2010) Pleural effusions from congestive heart failure. Semin Respir Crit Care Med 31(06):689–697
Porcel JM, Lui MM-S, Lerner AD et al (2017) Comparing approaches to the management of malignant pleural effusions. Expert Rev Respir Med 11(4):273–284
Shaw P, Agarwal R (2004) Pleurodesis for malignant pleural effusions. Cochrane Database Syst Rev 1:CD002916
Simon ST, Higginson IJ, Booth S et al (2010) Benzodiazepines for the relief of breathlessness in advanced malignant and non-malignant diseases in adults. Cochrane Database Syst Rev 1:CD007354
Simon ST, Higginson IJ, Booth S et al (2016) Benzodiazepines for the relief of breathlessness in advanced malignant and non-malignant diseases in adults. Cochrane Database Syst Rev 10:CD007354
Sitte T, Bausewein C (2008) Intranasal Fentanyl for episodic breathlessness. J Pain Symptom Manag 36(6):e3
Smith SM, Schroeder K, Fahey T (2014) Over-the-counter (OTC) medications for acute cough in children and adults in community settings. Cochrane Database Syst Rev 11:(CD001831)
Stenekes SJ, Hughes A, Grégoire M-C et al (2009) Frequency and self-management of pain, dyspnea, and cough in cystic fibrosis. J Pain Symptom Manag 38(6):837–848
Stingl JC, Rotthauwe J (2015) Codein: Neue Anwendungsbeschränkungen bei Kindern und Jugendlichen. Dtsch Med Wochenschr 140(14):1093–1095
Suri R, Metcalfe C, Lees B et al (2001) Comparison of hypertonic saline and alternate-day or daily recombinant human deoxyribonuclease in children with cystic fibrosis: a randomised trial. Lancet 358(9290):1316–1321
Thomas S, Bausewein C, Higginson IJ et al (2011) Breathlessness in cancer patients – Implications, management and challenges. Eur J Oncol Nurs 15:459–469
Truesdale K, Jurdi A (2013) Nebulized lidocaine in the treatment of intractable cough. Am J Hosp Palliat Care 30(6):587–589
Uronis HE, Currow DC, McCrory DC et al (2008) Oxygen for relief of dyspnoea in mildly-or non-hypoxaemic patients with cancer: a systematic review and meta-analysis. Br J Cancer 98(2):294–299
Uzbeck MH, Almeida FA, Sarkiss MG et al. (2010) Management of malignant pleural effusions. Adv Ther 27(6):334–47
Viola R, Kiteley C, Lloyd NS et al (2008) The management of dyspnea in cancer patients: a systematic review. Support Care Cancer 16(4):329–337
Walsh D, Donnelly S, Rybicki L (2000) The symptoms of advanced cancer: Relationshipn to age, gender, and performance status in 1,000 patients. Support Care Cancer 8(3):175–179
Wee B, Browning J, Adams A et al (2012) Management of chronic cough in patients receiving palliative care: review of evidence and recommendations by a task group of the Association for Palliative Medicine of Great Britain and Ireland. Palliat Med 26(6):780–787
Yancy WS Jr, McCrory DC, Coeytaux RR et al (2013) Efficacy and tolerability of treatments for chronic cough: a systematic review and meta-analysis. Chest 144(6):1827–1838
Yorke J, Moosavi SH, Shuldham C et al (2010) Quantification of dyspnoea using descriptors: development and initial testing of the Dyspnoea-12. Thorax 65(1):21–26
Zanasi A, Lanata L, Fontana G et al (2015) Levodropropizine for treating cough in adult and children: a meta-analysis of published studies. Multidiscip Respir Med 10(1):19
Zernikow B (Hrsg) (2021) Pädiatrische Palliativversorgung – Grundlagen, Bd 3. Springer, Berlin, Heidelberg
Zernikow B, Szybalski K, Hübner-Mohler B et al (2019) Specialized pediatric palliative care services for children dying from cancer: A repeated cohort study on the developments of symptom management and quality of care over a 10-year period. Palliat Med 33(3):381–391
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2022 Der/die Autor(en), exklusiv lizenziert durch Springer-Verlag GmbH, DE, ein Teil von Springer Nature
About this chapter
Cite this chapter
Printz, M., Zernikow, B., Baumann-Köhler, M., Pieper, S. (2022). Pulmonale Symptome. In: Zernikow, B. (eds) Pädiatrische Palliativversorgung – Schmerzbehandlung und Symptomkontrolle . Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-63148-5_5
Download citation
DOI: https://doi.org/10.1007/978-3-662-63148-5_5
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-63147-8
Online ISBN: 978-3-662-63148-5
eBook Packages: Medicine (German Language)