Zusammenfassung
Die multiple Sklerose (MS) ist vornehmlich eine entzündlich demyelinisierende Erkrankung des Zentralnervensystems, deren Hauptmerkmal rezidivierend auftretende schubförmige Manifestationen mit fokalen oder multifokalen neurologischen Ausfällen darstellen. Die Prävalenz für MS in Deutschland liegt bei etwa 200.000 Patienten. In der Ätiologie und Pathogenese werden drei Faktoren als bedeutend diskutiert: Einflüsse von Faktoren aus der Umwelt, Einflüsse genetischer Determinanten sowie eine autoimmune Reaktion.
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Faiss, J. (2020). Multiple Sklerose: Grundlagen. In: Berlit, P. (eds) Klinische Neurologie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-60676-6_157
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